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Murcko scaffold

5,6,7,8-Tetrahydroimidazo(1,5-a)pyrazine scaffold

191 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
191
With full pages
20
Scaffold SMILES

c1ncn2c1CNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydroimidazo(1,5-a)pyrazine page
Murcko scaffold c1ncn2c1CNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 191 chemicals

(5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazin-3-yl)methanol chemical structure, C7H11N3O, CAS 601515-87-1
(5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazin-3-yl)methanol
CAS 601515-87-1C7H11N3O
5,6,7,8-Tetrahydroimidazo(1,5-a)pyrazine chemical structure, C6H9N3, CAS 297172-19-1
5,6,7,8-Tetrahydroimidazo(1,5-a)pyrazine
CAS 297172-19-1C6H9N3
2-{5H,6H,7H,8H-Imidazo[1,5-a]pyrazin-3-yl}propan-2-ol chemical structure, C9H15N3O, CAS 722454-29-7
2-{5H,6H,7H,8H-Imidazo[1,5-a]pyrazin-3-yl}propan-2-ol
CAS 722454-29-7C9H15N3O
3-Bromo-7-methyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine chemical structure, C7H10BrN3, CAS 1542355-17-8
3-Bromo-7-methyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine
CAS 1542355-17-8C7H10BrN3
3-Isopropyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine chemical structure, C9H15N3, CAS 752200-12-7
3-Isopropyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine
CAS 752200-12-7C9H15N3
3-Methyl-5,6,7,8-tetrahydroimidazo(1,5-a)pyrazine chemical structure, C7H11N3, CAS 734531-00-1
3-Methyl-5,6,7,8-tetrahydroimidazo(1,5-a)pyrazine
CAS 734531-00-1C7H11N3
tert-Butyl 5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate chemical structure, C11H17N3O2, CAS 374795-76-3
tert-Butyl 5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate
CAS 374795-76-3C11H17N3O2
5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine 2,2,2-trifluoroacetate chemical structure, C8H10F3N3O2, CAS 374795-77-4
5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine 2,2,2-trifluoroacetate
CAS 374795-77-4C8H10F3N3O2
5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazin-3-amine chemical structure, C6H10N4, CAS 601515-56-4
5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazin-3-amine
CAS 601515-56-4C6H10N4
n,n-Dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazin-3-amine chemical structure, C8H14N4, CAS 601515-52-0
n,n-Dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazin-3-amine
CAS 601515-52-0C8H14N4
Imidazo[1,5-a]pyrazin-3-amine,5,6,7,8-tetrahydro-N-(2-methoxyethyl)-N-methyl- chemical structure, C10H18N4O, CAS 601515-53-1
Imidazo[1,5-a]pyrazin-3-amine,5,6,7,8-tetrahydro-N-(2-methoxyethyl)-N-methyl-
CAS 601515-53-1C10H18N4O
5,6,7,8-Tetrahydroimidazo[1,5-A]pyrazine hydrochloride chemical structure, C6H10ClN3, CAS 601515-49-5
5,6,7,8-Tetrahydroimidazo[1,5-A]pyrazine hydrochloride
CAS 601515-49-5C6H10ClN3
3-Methyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride chemical structure, C7H12ClN3, CAS 601515-50-8
3-Methyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride
CAS 601515-50-8C7H12ClN3
3-Ethyl-5,6,7,8-tetrahydroimidazo[1,5-A]pyrazine chemical structure, C8H13N3, CAS 601515-51-9
3-Ethyl-5,6,7,8-tetrahydroimidazo[1,5-A]pyrazine
CAS 601515-51-9C8H13N3
3-(Trifluoromethyl)-5H,6H,7H,8H-imidazo(1,5-a)pyrazine chemical structure, C7H8F3N3, CAS 959238-29-0
3-(Trifluoromethyl)-5H,6H,7H,8H-imidazo(1,5-a)pyrazine
CAS 959238-29-0C7H8F3N3
1-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine chemical structure, C6H8BrN3, CAS 1188265-59-9
1-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine
CAS 1188265-59-9C6H8BrN3
1-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride chemical structure, C6H9BrClN3, CAS 1188264-68-7
1-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride
CAS 1188264-68-7C6H9BrClN3
3-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine chemical structure, C6H8BrN3, CAS 944900-87-2
3-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine
CAS 944900-87-2C6H8BrN3
tert-Butyl 1-bromo-5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate chemical structure, C11H16BrN3O2, CAS 1188265-64-6
tert-Butyl 1-bromo-5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate
CAS 1188265-64-6C11H16BrN3O2
3-Chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine chemical structure, C6H8ClN3, CAS 944905-09-3
3-Chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine
CAS 944905-09-3C6H8ClN3
Ethyl 5,6,7,8-tetrahydroimidazo[1,5-A]pyrazine-1-carboxylate chemical structure, C9H13N3O2, CAS 951627-01-3
Ethyl 5,6,7,8-tetrahydroimidazo[1,5-A]pyrazine-1-carboxylate
CAS 951627-01-3C9H13N3O2
5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine dihydrochloride chemical structure, C6H11Cl2N3, CAS 165894-10-0
5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine dihydrochloride
CAS 165894-10-0C6H11Cl2N3
Imidazo[1,5-a]pyrazine-7(8H)-carboxylic acid,5,6-dihydro-3-(trifluoromethyl)-,1,1-dimethylethyl ester chemical structure, C12H16F3N3O2, CAS 1152440-01-1
Imidazo[1,5-a]pyrazine-7(8H)-carboxylic acid,5,6-dihydro-3-(trifluoromethyl)-,1,1-dimethylethyl ester
CAS 1152440-01-1C12H16F3N3O2
tert-Butyl 1-bromo-3-(trifluoromethyl)-5H,6H,7H,8H-imidazo(1,5-a)pyrazine-7-carboxylate chemical structure, C12H15BrF3N3O2, CAS 1152440-02-2
tert-Butyl 1-bromo-3-(trifluoromethyl)-5H,6H,7H,8H-imidazo(1,5-a)pyrazine-7-carboxylate
CAS 1152440-02-2C12H15BrF3N3O2