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Murcko scaffold

Ring system with 3 rings and 18 atoms

73 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
73
With full pages
14
Scaffold SMILES

O=c1cc(CN2CCNCC2)c2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(CN2CCNCC2)c2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 73 chemicals

6-Ethyl-4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)-2H-chromen-2-one chemical structure, C18H24N2O3, CAS 896072-11-0
6-Ethyl-4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)-2H-chromen-2-one
CAS 896072-11-0C18H24N2O3
6-Chloro-4-[(4-ethylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C16H19ClN2O2, CAS 896830-67-4
6-Chloro-4-[(4-ethylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 896830-67-4C16H19ClN2O2
4-{[4-(2-Hydroxyethyl)piperazin-1-yl]methyl}-7-methyl-2H-chromen-2-one chemical structure, C17H22N2O3, CAS 899383-90-5
4-{[4-(2-Hydroxyethyl)piperazin-1-yl]methyl}-7-methyl-2H-chromen-2-one
CAS 899383-90-5C17H22N2O3
4-{[4-(2-Hydroxyethyl)piperazin-1-yl]methyl}-5,7-dimethyl-2H-chromen-2-one chemical structure, C18H24N2O3, CAS 899384-00-0
4-{[4-(2-Hydroxyethyl)piperazin-1-yl]methyl}-5,7-dimethyl-2H-chromen-2-one
CAS 899384-00-0C18H24N2O3
6-Chloro-4-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C15H17ClN2O2, CAS 899388-35-3
6-Chloro-4-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 899388-35-3C15H17ClN2O2
5,7-Dimethyl-4-((4-methylpiperazin-1-yl)methyl)-2H-chromen-2-one chemical structure, C17H22N2O2, CAS 900272-23-3
5,7-Dimethyl-4-((4-methylpiperazin-1-yl)methyl)-2H-chromen-2-one
CAS 900272-23-3C17H22N2O2
4-[(4-Ethyl-1-piperazinyl)methyl]-5,7-dimethyl-1-benzopyran-2-one chemical structure, C18H24N2O2, CAS 900284-01-7
4-[(4-Ethyl-1-piperazinyl)methyl]-5,7-dimethyl-1-benzopyran-2-one
CAS 900284-01-7C18H24N2O2
Ethyl 4-[(6-chloro-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C17H19ClN2O4, CAS 900291-40-9
Ethyl 4-[(6-chloro-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate
CAS 900291-40-9C17H19ClN2O4
Ethyl 4-[(7,8-dimethyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C19H24N2O4, CAS 844823-03-6
Ethyl 4-[(7,8-dimethyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate
CAS 844823-03-6C19H24N2O4
Ethyl 4-[(7-methoxy-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C18H22N2O5, CAS 859858-83-6
Ethyl 4-[(7-methoxy-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859858-83-6C18H22N2O5
Ethyl 4-[(7-methyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C18H22N2O4, CAS 859858-84-7
Ethyl 4-[(7-methyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859858-84-7C18H22N2O4
Ethyl 4-[(6-hydroxy-7-methyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C18H22N2O5, CAS 859859-66-8
Ethyl 4-[(6-hydroxy-7-methyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859859-66-8C18H22N2O5
Ethyl 4-[(6,7-dimethyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C19H24N2O4, CAS 849055-60-3
Ethyl 4-[(6,7-dimethyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate
CAS 849055-60-3C19H24N2O4
Ethyl 4-[(6-hydroxy-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C17H20N2O5, CAS 859859-78-2
Ethyl 4-[(6-hydroxy-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859859-78-2C17H20N2O5
Ethyl 4-[(6-methyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C18H22N2O4, CAS 859860-51-8
Ethyl 4-[(6-methyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859860-51-8C18H22N2O4
Ethyl 4-[(6-ethyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C19H24N2O4, CAS 859111-28-7
Ethyl 4-[(6-ethyl-2-oxo-2H-chromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859111-28-7C19H24N2O4
Ethyl 4-[(6,8-dimethyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C19H24N2O4, CAS 859116-74-8
Ethyl 4-[(6,8-dimethyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859116-74-8C19H24N2O4
Ethyl 4-((6-isopropyl-2-oxo-2H-chromen-4-yl)methyl)piperazine-1-carboxylate chemical structure, C20H26N2O4, CAS 859126-07-1
Ethyl 4-((6-isopropyl-2-oxo-2H-chromen-4-yl)methyl)piperazine-1-carboxylate
CAS 859126-07-1C20H26N2O4
Ethyl 4-[(5,7-dimethyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate chemical structure, C19H24N2O4, CAS 859127-36-9
Ethyl 4-[(5,7-dimethyl-2-oxochromen-4-yl)methyl]piperazine-1-carboxylate
CAS 859127-36-9C19H24N2O4
4-((4-Ethylpiperazin-1-yl)methyl)-6-methyl-2H-chromen-2-one chemical structure, C17H22N2O2, CAS 896814-82-7
4-((4-Ethylpiperazin-1-yl)methyl)-6-methyl-2H-chromen-2-one
CAS 896814-82-7C17H22N2O2
6-Hydroxy-7-methyl-4-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C16H20N2O3, CAS 896821-59-3
6-Hydroxy-7-methyl-4-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 896821-59-3C16H20N2O3
6-Chloro-4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)-7-methyl-2H-chromen-2-one chemical structure, C17H21ClN2O3, CAS 896825-62-0
6-Chloro-4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)-7-methyl-2H-chromen-2-one
CAS 896825-62-0C17H21ClN2O3
6-Ethyl-4-((4-ethylpiperazin-1-yl)methyl)-2H-chromen-2-one chemical structure, C18H24N2O2, CAS 896830-15-2
6-Ethyl-4-((4-ethylpiperazin-1-yl)methyl)-2H-chromen-2-one
CAS 896830-15-2C18H24N2O2
6-Ethyl-4-((4-methylpiperazin-1-yl)methyl)-2H-chromen-2-one chemical structure, C17H22N2O2, CAS 896836-32-1
6-Ethyl-4-((4-methylpiperazin-1-yl)methyl)-2H-chromen-2-one
CAS 896836-32-1C17H22N2O2