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Murcko scaffold

4-(Pyrimidin-4-yl)morpholine scaffold

324 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
324
With full pages
21
Scaffold SMILES

c1cc(N2CCOCC2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyrimidin-4-yl)morpholine page
Murcko scaffold c1cc(N2CCOCC2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 324 chemicals

Acetic acid, ((6-(4-morpholinyl)-4-pyrimidinyl)thio)-, hydrazide chemical structure, C10H15N5O2S, CAS 95546-90-0
Acetic acid, ((6-(4-morpholinyl)-4-pyrimidinyl)thio)-, hydrazide
CAS 95546-90-0C10H15N5O2S
Acetic acid, ((6-(4-morpholinyl)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide chemical structure, C13H19N5O2S, CAS 95546-93-3
Acetic acid, ((6-(4-morpholinyl)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide
CAS 95546-93-3C13H19N5O2S
6-(Morpholin-4-yl)pyrimidine-4,5-diamine chemical structure, C8H13N5O, CAS 24957-90-2
6-(Morpholin-4-yl)pyrimidine-4,5-diamine
CAS 24957-90-2C8H13N5O
6-(Morpholin-4-yl)-5-nitropyrimidin-4-amine chemical structure, C8H11N5O3, CAS 24957-88-8
6-(Morpholin-4-yl)-5-nitropyrimidin-4-amine
CAS 24957-88-8C8H11N5O3
4-[6-(Methylsulfonyl)pyrimidin-4-yl]morpholine chemical structure, C9H13N3O3S, CAS 90648-76-3
4-[6-(Methylsulfonyl)pyrimidin-4-yl]morpholine
CAS 90648-76-3C9H13N3O3S
Ethyl 2-(methylsulfanyl)-4-morpholino-5-pyrimidinecarboxylate chemical structure, C12H17N3O3S, CAS 100318-76-1
Ethyl 2-(methylsulfanyl)-4-morpholino-5-pyrimidinecarboxylate
CAS 100318-76-1C12H17N3O3S
2-Amino-4-morpholin-4-yl-pyrimidine chemical structure, C8H12N4O, CAS 861031-56-3
2-Amino-4-morpholin-4-yl-pyrimidine
CAS 861031-56-3C8H12N4O
4-(5-Fluoro-2-hydrazinylpyrimidin-4-yl)morpholine chemical structure, C8H12FN5O, CAS 118121-89-4
4-(5-Fluoro-2-hydrazinylpyrimidin-4-yl)morpholine
CAS 118121-89-4C8H12FN5O
2,2,2-Trichloro-N-(6-morpholin-4-ylpyrimidin-4-yl)acetamide chemical structure, C10H11Cl3N4O2, CAS 781657-09-8
2,2,2-Trichloro-N-(6-morpholin-4-ylpyrimidin-4-yl)acetamide
CAS 781657-09-8C10H11Cl3N4O2
Acetic acid, ((4-methyl-6-(4-morpholinyl)-2-pyrimidinyl)thio)- chemical structure, C11H15N3O3S, CAS 92628-88-1
Acetic acid, ((4-methyl-6-(4-morpholinyl)-2-pyrimidinyl)thio)-
CAS 92628-88-1C11H15N3O3S
4-(6-Chloropyrimidin-4-yl)morpholine chemical structure, C8H10ClN3O, CAS 22177-92-0
4-(6-Chloropyrimidin-4-yl)morpholine
CAS 22177-92-0C8H10ClN3O
5-Ethyl-4-methyl-6-(morpholin-4-yl)pyrimidin-2-amine chemical structure, C11H18N4O, CAS 424813-05-8
5-Ethyl-4-methyl-6-(morpholin-4-yl)pyrimidin-2-amine
CAS 424813-05-8C11H18N4O
4-Chloro-6-morpholin-4-yl-pyrimidin-5-ylamine chemical structure, C8H11ClN4O, CAS 84762-69-6
4-Chloro-6-morpholin-4-yl-pyrimidin-5-ylamine
CAS 84762-69-6C8H11ClN4O
4-[6-(Methoxymethyl)-2-methylpyrimidin-4-yl]morpholine chemical structure, C11H17N3O2, CAS 478043-19-5
4-[6-(Methoxymethyl)-2-methylpyrimidin-4-yl]morpholine
CAS 478043-19-5C11H17N3O2
4-[6-(Methoxymethyl)-2-(methylsulfanyl)-4-pyrimidinyl]morpholine chemical structure, C11H17N3O2S, CAS 338748-03-1
4-[6-(Methoxymethyl)-2-(methylsulfanyl)-4-pyrimidinyl]morpholine
CAS 338748-03-1C11H17N3O2S
4-Chloro-6-(morpholin-4-yl)pyrimidin-2-amine chemical structure, C8H11ClN4O, CAS 339016-18-1
4-Chloro-6-(morpholin-4-yl)pyrimidin-2-amine
CAS 339016-18-1C8H11ClN4O
4-[6-Chloro-2-(methylsulfanyl)-4-pyrimidinyl]morpholine chemical structure, C9H12ClN3OS, CAS 339016-21-6
4-[6-Chloro-2-(methylsulfanyl)-4-pyrimidinyl]morpholine
CAS 339016-21-6C9H12ClN3OS
4-[2-(Methylsulfanyl)-6-(trifluoromethyl)-4-pyrimidinyl]morpholine chemical structure, C10H12F3N3OS, CAS 339019-56-6
4-[2-(Methylsulfanyl)-6-(trifluoromethyl)-4-pyrimidinyl]morpholine
CAS 339019-56-6C10H12F3N3OS
N-Ethyl-2-(methylsulfanyl)-6-morpholino-4-pyrimidinamine chemical structure, C11H18N4OS, CAS 478258-66-1
N-Ethyl-2-(methylsulfanyl)-6-morpholino-4-pyrimidinamine
CAS 478258-66-1C11H18N4OS
4-Chloro-N-methyl-5-(methylsulfanyl)-6-morpholino-2-pyrimidinamine chemical structure, C10H15ClN4OS, CAS 83199-51-3
4-Chloro-N-methyl-5-(methylsulfanyl)-6-morpholino-2-pyrimidinamine
CAS 83199-51-3C10H15ClN4OS
4-(2-Chloropyrimidin-4-yl)morpholine chemical structure, C8H10ClN3O, CAS 62968-37-0
4-(2-Chloropyrimidin-4-yl)morpholine
CAS 62968-37-0C8H10ClN3O
5-Bromo-2-chloro-4-morpholinopyrimidine chemical structure, C8H9BrClN3O, CAS 139502-01-5
5-Bromo-2-chloro-4-morpholinopyrimidine
CAS 139502-01-5C8H9BrClN3O
2-Chloro-6-morpholinopyrimidin-4-amine chemical structure, C8H11ClN4O, CAS 330993-04-9
2-Chloro-6-morpholinopyrimidin-4-amine
CAS 330993-04-9C8H11ClN4O
N-(3-Hydroxypropyl)-2-((4-methyl-6-morpholinopyrimidin-2-yl)thio)acetamide chemical structure, C14H22N4O3S, CAS 393518-13-3
N-(3-Hydroxypropyl)-2-((4-methyl-6-morpholinopyrimidin-2-yl)thio)acetamide
CAS 393518-13-3C14H22N4O3S