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Murcko scaffold

Ring system with 3 rings and 15 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
6
With full pages
3
Scaffold SMILES

c1ccc(-c2ccnc3ccnn23)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc3ccnn23)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-Methyl-7-(2-pyridinyl)pyrazolo[1,5-a]pyrimidine chemical structure, C12H10N4, CAS 186956-71-8
2-Methyl-7-(2-pyridinyl)pyrazolo[1,5-a]pyrimidine
CAS 186956-71-8C12H10N4
7-(2-Pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C12H7N5, CAS 320417-17-2
7-(2-Pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 320417-17-2C12H7N5
3-Bromo-2-methyl-7-(2-pyridinyl)pyrazolo[1,5-a]pyrimidine chemical structure, C12H9BrN4, CAS 860610-14-6
3-Bromo-2-methyl-7-(2-pyridinyl)pyrazolo[1,5-a]pyrimidine
CAS 860610-14-6C12H9BrN4
3-Chloro-2-methyl-7-(2-pyridinyl)pyrazolo[1,5-a]pyrimidine chemical structure, C12H9ClN4, CAS 439120-66-8
3-Chloro-2-methyl-7-(2-pyridinyl)pyrazolo[1,5-a]pyrimidine
CAS 439120-66-8C12H9ClN4
Ethyl 7-(pyridin-2-yl)pyrazolo[1,5-A]pyrimidine-3-carboxylate chemical structure, C14H12N4O2, CAS 78562-50-2
Ethyl 7-(pyridin-2-yl)pyrazolo[1,5-A]pyrimidine-3-carboxylate
CAS 78562-50-2C14H12N4O2
7-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methylpyrazolo[1,5-a]pyrimidine chemical structure, C13H8ClF3N4, CAS 1092346-62-7
7-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methylpyrazolo[1,5-a]pyrimidine
CAS 1092346-62-7C13H8ClF3N4