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Murcko scaffold

Ring system with 3 rings and 17 atoms

42 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
42
With full pages
9
Scaffold SMILES

c1ccc(-n2ccc(-c3cccnc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2ccc(-c3cccnc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

(1-Phenyl-3-pyridin-3-yl-1H-pyrazol-4-yl)-methanol chemical structure, C15H13N3O, CAS 5965-96-8
(1-Phenyl-3-pyridin-3-yl-1H-pyrazol-4-yl)-methanol
CAS 5965-96-8C15H13N3O
1-Phenyl-3-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C15H11N3O2, CAS 372107-42-1
1-Phenyl-3-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid
CAS 372107-42-1C15H11N3O2
1-Phenyl-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H11N3O, CAS 36640-50-3
1-Phenyl-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 36640-50-3C15H11N3O
2-Cyano-3-[1-phenyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]prop-2-enamide chemical structure, C18H13N5O
2-Cyano-3-[1-phenyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]prop-2-enamide
C18H13N5O
(Z)-2-Cyano-3-(1-phenyl-3-pyridin-3-ylpyrazol-4-yl)prop-2-enamide chemical structure, C18H13N5O, CAS 1322238-12-9
(Z)-2-Cyano-3-(1-phenyl-3-pyridin-3-ylpyrazol-4-yl)prop-2-enamide
CAS 1322238-12-9C18H13N5O
2-((1-Phenyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methylene)malononitrile chemical structure, C18H11N5, CAS 423728-77-2
2-((1-Phenyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methylene)malononitrile
CAS 423728-77-2C18H11N5
1-Phenyl-3-(pyridin-3-yl)-1H-pyrazole-4-carboxamide chemical structure, C15H12N4O, CAS 882231-15-4
1-Phenyl-3-(pyridin-3-yl)-1H-pyrazole-4-carboxamide
CAS 882231-15-4C15H12N4O
Methyl 3-(3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylate chemical structure, C17H12F3N3O2, CAS 400076-48-4
Methyl 3-(3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylate
CAS 400076-48-4C17H12F3N3O2
3-Pyridin-3-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-4-carboxylic acid chemical structure, C16H10F3N3O2, CAS 400076-50-8
3-Pyridin-3-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-4-carboxylic acid
CAS 400076-50-8C16H10F3N3O2
N-Methyl-3-(3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide chemical structure, C17H13F3N4O, CAS 400076-53-1
N-Methyl-3-(3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide
CAS 400076-53-1C17H13F3N4O
3-[1-Phenyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]prop-2-enoic acid chemical structure, C17H13N3O2, CAS 519137-45-2
3-[1-Phenyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]prop-2-enoic acid
CAS 519137-45-2C17H13N3O2
Ethyl 2-phenyl-5-pyridin-3-ylpyrazole-3-carboxylate chemical structure, C17H15N3O2, CAS 380432-10-0
Ethyl 2-phenyl-5-pyridin-3-ylpyrazole-3-carboxylate
CAS 380432-10-0C17H15N3O2
(1-(2-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol chemical structure, C15H12FN3O, CAS 618383-42-9
(1-(2-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol
CAS 618383-42-9C15H12FN3O
1-(4-Bromophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H10BrN3O, CAS 618099-05-1
1-(4-Bromophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 618099-05-1C15H10BrN3O
(1-(4-Methoxyphenyl)-3-(3-pyridinyl)-1H-pyrazol-4-yl)methanol chemical structure, C16H15N3O2, CAS 618383-39-4
(1-(4-Methoxyphenyl)-3-(3-pyridinyl)-1H-pyrazol-4-yl)methanol
CAS 618383-39-4C16H15N3O2
1-(4-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H10FN3O, CAS 618101-63-6
1-(4-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 618101-63-6C15H10FN3O
(3-(Pyridin-3-yl)-1-(m-tolyl)-1H-pyrazol-4-yl)methanol chemical structure, C16H15N3O, CAS 618441-91-1
(3-(Pyridin-3-yl)-1-(m-tolyl)-1H-pyrazol-4-yl)methanol
CAS 618441-91-1C16H15N3O
3-(Pyridin-3-yl)-1-P-tolyl-1H-pyrazole-4-carbaldehyde chemical structure, C16H13N3O, CAS 618098-93-4
3-(Pyridin-3-yl)-1-P-tolyl-1H-pyrazole-4-carbaldehyde
CAS 618098-93-4C16H13N3O
1-(4-Chlorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H10ClN3O, CAS 618099-00-6
1-(4-Chlorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 618099-00-6C15H10ClN3O
1-(2-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H10FN3O, CAS 618101-79-4
1-(2-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 618101-79-4C15H10FN3O
1-(3-Chlorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H10ClN3O, CAS 618101-73-8
1-(3-Chlorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 618101-73-8C15H10ClN3O
(1-(4-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol chemical structure, C15H12FN3O, CAS 618444-47-6
(1-(4-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol
CAS 618444-47-6C15H12FN3O
(1-(2,4-Difluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol chemical structure, C15H11F2N3O, CAS 618444-49-8
(1-(2,4-Difluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol
CAS 618444-49-8C15H11F2N3O
1-(4-Methoxyphenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C16H13N3O2, CAS 618101-69-2
1-(4-Methoxyphenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 618101-69-2C16H13N3O2