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Murcko scaffold

Ring system with 3 rings and 21 atoms

29 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
29
With full pages
3
Scaffold SMILES

O=C(CCn1c(=O)sc2ccccc21)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCn1c(=O)sc2ccccc21)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

N-(2-Methylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C17H16N2O2S, CAS 851989-84-9
N-(2-Methylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 851989-84-9C17H16N2O2S
N-(4-Methoxyphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C17H16N2O3S, CAS 851989-94-1
N-(4-Methoxyphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 851989-94-1C17H16N2O3S
N-(3-Acetylphenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide chemical structure, C18H16N2O3S, CAS 851989-99-6
N-(3-Acetylphenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
CAS 851989-99-6C18H16N2O3S
N-(2,4-Difluorophenyl)-3-(2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)propanamide chemical structure, C16H12F2N2O2S, CAS 851990-02-8
N-(2,4-Difluorophenyl)-3-(2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)propanamide
CAS 851990-02-8C16H12F2N2O2S
N-(2,5-Difluorophenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide chemical structure, C16H12F2N2O2S, CAS 851990-04-0
N-(2,5-Difluorophenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
CAS 851990-04-0C16H12F2N2O2S
N-(2,3-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide chemical structure, C18H18N2O2S, CAS 852046-15-2
N-(2,3-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
CAS 852046-15-2C18H18N2O2S
N-(2,4-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C18H18N2O2S, CAS 852046-16-3
N-(2,4-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 852046-16-3C18H18N2O2S
N-(2,5-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C18H18N2O2S, CAS 852046-17-4
N-(2,5-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 852046-17-4C18H18N2O2S
N-(3,4-Dimethylphenyl)-3-(2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)propanamide chemical structure, C18H18N2O2S, CAS 852046-18-5
N-(3,4-Dimethylphenyl)-3-(2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)propanamide
CAS 852046-18-5C18H18N2O2S
N-(3,5-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C18H18N2O2S, CAS 852046-19-6
N-(3,5-Dimethylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 852046-19-6C18H18N2O2S
N-(3-Chloro-2-methylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C17H15ClN2O2S, CAS 852046-22-1
N-(3-Chloro-2-methylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 852046-22-1C17H15ClN2O2S
N-(3-Chloro-4-methylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C17H15ClN2O2S, CAS 852046-23-2
N-(3-Chloro-4-methylphenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 852046-23-2C17H15ClN2O2S
N-(2,3-Dichlorophenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide chemical structure, C16H12Cl2N2O2S, CAS 853751-86-7
N-(2,3-Dichlorophenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
CAS 853751-86-7C16H12Cl2N2O2S
N-(2,5-Dichlorophenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide chemical structure, C16H12Cl2N2O2S, CAS 853902-06-4
N-(2,5-Dichlorophenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
CAS 853902-06-4C16H12Cl2N2O2S
N-[2-(Methylthio)phenyl]-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C17H16N2O2S2, CAS 851989-97-4
N-[2-(Methylthio)phenyl]-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 851989-97-4C17H16N2O2S2
N-[5-(Acetylamino)-2-methoxyphenyl]-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C19H19N3O4S, CAS 852046-40-3
N-[5-(Acetylamino)-2-methoxyphenyl]-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 852046-40-3C19H19N3O4S
N-[3-(Acetylamino)phenyl]-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C18H17N3O3S, CAS 852046-37-8
N-[3-(Acetylamino)phenyl]-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 852046-37-8C18H17N3O3S
3-(2-Oxobenzo[d]thiazol-3(2H)-yl)-N-(m-tolyl)propanamide chemical structure, C17H16N2O2S, CAS 851989-85-0
3-(2-Oxobenzo[d]thiazol-3(2H)-yl)-N-(m-tolyl)propanamide
CAS 851989-85-0C17H16N2O2S
N-(4-Methylphenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide chemical structure, C17H16N2O2S, CAS 847480-22-2
N-(4-Methylphenyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
CAS 847480-22-2C17H16N2O2S
N-(2-Fluorophenyl)-3-(2-oxobenzo[d]thiazol-3(2H)-yl)propanamide chemical structure, C16H13FN2O2S, CAS 862827-82-5
N-(2-Fluorophenyl)-3-(2-oxobenzo[d]thiazol-3(2H)-yl)propanamide
CAS 862827-82-5C16H13FN2O2S
N-(4-Fluoro-3-nitrophenyl)-3-(2-oxobenzo[d]thiazol-3(2H)-yl)propanamide chemical structure, C16H12FN3O4S, CAS 862973-81-7
N-(4-Fluoro-3-nitrophenyl)-3-(2-oxobenzo[d]thiazol-3(2H)-yl)propanamide
CAS 862973-81-7C16H12FN3O4S
N-(3-Bromophenyl)-3-(2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)propanamide chemical structure, C16H13BrN2O2S, CAS 851989-91-8
N-(3-Bromophenyl)-3-(2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)propanamide
CAS 851989-91-8C16H13BrN2O2S
N-(4-Bromophenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide chemical structure, C16H13BrN2O2S, CAS 851989-92-9
N-(4-Bromophenyl)-3-(2-oxo-1,3-benzothiazol-3(2H)-yl)propanamide
CAS 851989-92-9C16H13BrN2O2S
3-(2-Oxo-1,3-benzothiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]propanamide chemical structure, C17H13F3N2O3S, CAS 851989-96-3
3-(2-Oxo-1,3-benzothiazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]propanamide
CAS 851989-96-3C17H13F3N2O3S