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Murcko scaffold

1H-Pyrazol-3-ol scaffold

601 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
601
With full pages
84
Scaffold SMILES

O=c1cc[nH][nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1H-Pyrazol-3-ol page
Murcko scaffold O=c1cc[nH][nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 601 chemicals

3-Amino-5-hydroxypyrazole chemical structure, C3H5N3O, CAS 28491-52-3
3-Amino-5-hydroxypyrazole
CAS 28491-52-3C3H5N3O
Ethyl 2,3-dihydro-3-oxo-1H-pyrazole-4-carboxylate chemical structure, C6H8N2O3, CAS 7251-53-8
Ethyl 2,3-dihydro-3-oxo-1H-pyrazole-4-carboxylate
CAS 7251-53-8C6H8N2O3
5-Amino-1-methyl-2,3-dihydro-1H-pyrazol-3-one chemical structure, C4H7N3O, CAS 54167-77-0
5-Amino-1-methyl-2,3-dihydro-1H-pyrazol-3-one
CAS 54167-77-0C4H7N3O
4,5-Diamino-1,2-dihydro-3-oxopyrazole sulphate chemical structure, C3H8N4O5S, CAS 97358-51-5
4,5-Diamino-1,2-dihydro-3-oxopyrazole sulphate
CAS 97358-51-5C3H8N4O5S
5-Amino-4-nitroso-1,2-dihydro-3H-pyrazol-3-one chemical structure, C3H4N4O2, CAS 75524-41-3
5-Amino-4-nitroso-1,2-dihydro-3H-pyrazol-3-one
CAS 75524-41-3C3H4N4O2
Methyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate chemical structure, C6H8N2O3, CAS 52867-42-2
Methyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate
CAS 52867-42-2C6H8N2O3
RefChem:381771 chemical structure, C4H5N3O2, CAS 6386-15-8
RefChem:381771
CAS 6386-15-8C4H5N3O2
3-Methyl-3-pyrazolin-5-one chemical structure, C4H6N2O, CAS 4344-87-0
3-Methyl-3-pyrazolin-5-one
CAS 4344-87-0C4H6N2O
2-(5-Oxo-1,2-dihydropyrazol-3-yl)acetohydrazide chemical structure, C5H8N4O2, CAS 58979-86-5
2-(5-Oxo-1,2-dihydropyrazol-3-yl)acetohydrazide
CAS 58979-86-5C5H8N4O2
Methyl 2-(3-hydroxy-1H-pyrazol-5-yl)acetate chemical structure, C6H8N2O3, CAS 58979-88-7
Methyl 2-(3-hydroxy-1H-pyrazol-5-yl)acetate
CAS 58979-88-7C6H8N2O3
1,5-Dimethyl-4-nitro-1,2-dihydro-3H-pyrazol-3-one chemical structure, C5H7N3O3, CAS 61885-22-1
1,5-Dimethyl-4-nitro-1,2-dihydro-3H-pyrazol-3-one
CAS 61885-22-1C5H7N3O3
5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester chemical structure, C6H8N2O3, CAS 51985-95-6
5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS 51985-95-6C6H8N2O3
5-Hydroxy-alpha-methyl-1H-pyrazole-3-methanol chemical structure, C5H8N2O2, CAS 70498-82-7
5-Hydroxy-alpha-methyl-1H-pyrazole-3-methanol
CAS 70498-82-7C5H8N2O2
5-(2-Hydroxypropan-2-yl)-2-methyl-1H-pyrazol-3-one chemical structure, C7H12N2O2, CAS 70498-88-3
5-(2-Hydroxypropan-2-yl)-2-methyl-1H-pyrazol-3-one
CAS 70498-88-3C7H12N2O2
1H-Pyrazol-3-ol chemical structure, C3H4N2O, CAS 60456-92-0
1H-Pyrazol-3-ol
CAS 60456-92-0C3H4N2O
4-(2-Hydroxyethyl)-3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-carboximidamide chemical structure, C7H12N4O2, CAS 210417-12-2
4-(2-Hydroxyethyl)-3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-carboximidamide
CAS 210417-12-2C7H12N4O2
5-Oxo-2,5-dihydro-1H-pyrazole-3-carbohydrazide chemical structure, C4H6N4O2, CAS 66483-27-0
5-Oxo-2,5-dihydro-1H-pyrazole-3-carbohydrazide
CAS 66483-27-0C4H6N4O2
3-Amino-5-oxo-1H-pyrazole-2-carboxamide chemical structure, C4H6N4O2, CAS 119768-91-1
3-Amino-5-oxo-1H-pyrazole-2-carboxamide
CAS 119768-91-1C4H6N4O2
1,5-Dimethyl-2,3-dihydro-1H-pyrazol-3-one chemical structure, C5H8N2O, CAS 3201-28-3
1,5-Dimethyl-2,3-dihydro-1H-pyrazol-3-one
CAS 3201-28-3C5H8N2O
Ethyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate chemical structure, C7H10N2O3, CAS 40711-34-0
Ethyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate
CAS 40711-34-0C7H10N2O3
5-Amino-1-sec-butyl-1H-pyrazol-3-ol chemical structure, C7H13N3O, CAS 436088-85-6
5-Amino-1-sec-butyl-1H-pyrazol-3-ol
CAS 436088-85-6C7H13N3O
5-Amino-1-(pentan-3-yl)-1,2-dihydro-3H-pyrazol-3-one chemical structure, C8H15N3O, CAS 727675-81-2
5-Amino-1-(pentan-3-yl)-1,2-dihydro-3H-pyrazol-3-one
CAS 727675-81-2C8H15N3O
5-Amino-1-isopropyl-1H-pyrazol-3-ol chemical structure, C6H11N3O, CAS 78317-68-7
5-Amino-1-isopropyl-1H-pyrazol-3-ol
CAS 78317-68-7C6H11N3O
Ethyl 5-hydroxy-1-[(methylamino)carbonyl]-1H-pyrazole-3-carboxylate chemical structure, C8H11N3O4, CAS 1017795-09-3
Ethyl 5-hydroxy-1-[(methylamino)carbonyl]-1H-pyrazole-3-carboxylate
CAS 1017795-09-3C8H11N3O4