CompoundList
Sign in
Murcko scaffold

2-(2-(Pyridin-2-yl)ethyl)-1H-isoindole-1,3(2H)-dione scaffold

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
8
With full pages
2
Scaffold SMILES

O=C1c2ccccc2C(=O)N1CCc1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2-(Pyridin-2-yl)ethyl)-1H-isoindole-1,3(2H)-dione page
Murcko scaffold O=C1c2ccccc2C(=O)N1CCc1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-[2-(5-Ethylpyridin-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione chemical structure, C17H16N2O2, CAS 17624-24-7
2-[2-(5-Ethylpyridin-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione
CAS 17624-24-7C17H16N2O2
2-(2-(Pyridin-2-yl)ethyl)-1H-isoindole-1,3(2H)-dione chemical structure, C15H12N2O2, CAS 17624-26-9
2-(2-(Pyridin-2-yl)ethyl)-1H-isoindole-1,3(2H)-dione
CAS 17624-26-9C15H12N2O2
Win-3074 chemical structure, C15H13ClN2O2, CAS 97174-79-3
Win-3074
CAS 97174-79-3C15H13ClN2O2
1H-Isoindole-1,3(2H)-dione, 2-[2-(6-methoxy-2-pyridinyl)ethyl]- chemical structure, C16H14N2O3, CAS 195819-18-2
1H-Isoindole-1,3(2H)-dione, 2-[2-(6-methoxy-2-pyridinyl)ethyl]-
CAS 195819-18-2C16H14N2O3
Diethyl 2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]-2-[(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)methyl]malonate chemical structure, C22H18ClF3N2O6, CAS 1307316-10-4
Diethyl 2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]-2-[(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)methyl]malonate
CAS 1307316-10-4C22H18ClF3N2O6
2-[2-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-ethyl]-isoindole-1,3-dione chemical structure, C16H10ClF3N2O2, CAS 326816-36-8
2-[2-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-ethyl]-isoindole-1,3-dione
CAS 326816-36-8C16H10ClF3N2O2
2-[2-(5-Methylpyridin-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione chemical structure, C16H14N2O2, CAS 830348-33-9
2-[2-(5-Methylpyridin-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione
CAS 830348-33-9C16H14N2O2
2-(2-(6-Aminopyridin-2-yl)ethyl)isoindoline-1,3-dione chemical structure, C15H13N3O2, CAS 400775-89-5
2-(2-(6-Aminopyridin-2-yl)ethyl)isoindoline-1,3-dione
CAS 400775-89-5C15H13N3O2