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Murcko scaffold

Ring system with 3 rings and 16 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
11
With full pages
3
Scaffold SMILES

O=c1[nH]c2ccccc2cc1-c1ncon1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2ccccc2cc1-c1ncon1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-(5-Ethyl-[1,2,4]oxadiazol-3-yl)-7-methyl-quinolin-2-ol chemical structure, C14H13N3O2, CAS 714292-68-9
3-(5-Ethyl-[1,2,4]oxadiazol-3-yl)-7-methyl-quinolin-2-ol
CAS 714292-68-9C14H13N3O2
6-Methyl-3-(5-propyl-[1,2,4]oxadiazol-3-yl)-quinolin-2-ol chemical structure, C15H15N3O2, CAS 714252-85-4
6-Methyl-3-(5-propyl-[1,2,4]oxadiazol-3-yl)-quinolin-2-ol
CAS 714252-85-4C15H15N3O2
3-(5-Ethyl-1,2,4-oxadiazol-3-yl)-6-methylquinolin-2-ol chemical structure, C14H13N3O2, CAS 245121-57-7
3-(5-Ethyl-1,2,4-oxadiazol-3-yl)-6-methylquinolin-2-ol
CAS 245121-57-7C14H13N3O2
3-(5-Isopropyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol chemical structure, C14H13N3O2, CAS 245121-34-0
3-(5-Isopropyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol
CAS 245121-34-0C14H13N3O2
3-(5-Isobutyl-[1,2,4]oxadiazol-3-yl)-6-methyl-quinolin-2-ol chemical structure, C16H17N3O2, CAS 714915-89-6
3-(5-Isobutyl-[1,2,4]oxadiazol-3-yl)-6-methyl-quinolin-2-ol
CAS 714915-89-6C16H17N3O2
7-Methyl-3-(5-methyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol chemical structure, C13H11N3O2, CAS 704874-10-2
7-Methyl-3-(5-methyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol
CAS 704874-10-2C13H11N3O2
3-(5-Ethyl-1,2,4-oxadiazol-3-yl)quinolin-2(1H)-one chemical structure, C13H11N3O2, CAS 245121-50-0
3-(5-Ethyl-1,2,4-oxadiazol-3-yl)quinolin-2(1H)-one
CAS 245121-50-0C13H11N3O2
6-Methyl-3-(5-methyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol chemical structure, C13H11N3O2, CAS 245121-55-5
6-Methyl-3-(5-methyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol
CAS 245121-55-5C13H11N3O2
3-(5-Methyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol chemical structure, C12H9N3O2, CAS 245121-31-7
3-(5-Methyl-1,2,4-oxadiazol-3-yl)quinolin-2-ol
CAS 245121-31-7C12H9N3O2
3-(1,2-Dihydro-7-methyl-2-oxo-3-quinolinyl)-1,2,4-oxadiazole-5-propanoic acid chemical structure, C15H13N3O4, CAS 1119505-57-5
3-(1,2-Dihydro-7-methyl-2-oxo-3-quinolinyl)-1,2,4-oxadiazole-5-propanoic acid
CAS 1119505-57-5C15H13N3O4
3-(3-(2-Hydroxy-8-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl)propanoic acid chemical structure, C15H13N3O4, CAS 1119394-90-9
3-(3-(2-Hydroxy-8-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl)propanoic acid
CAS 1119394-90-9C15H13N3O4