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Murcko scaffold

2-(3,5-Dioxothiomorpholino)-N-phenylacetamide scaffold

86 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
86
With full pages
13
Scaffold SMILES

O=C(CN1C(=O)CSCC1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(3,5-Dioxothiomorpholino)-N-phenylacetamide page
Murcko scaffold O=C(CN1C(=O)CSCC1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 86 chemicals

2-(3,5-Dioxothiomorpholino)-N-phenylacetamide chemical structure, C12H12N2O3S, CAS 868215-00-3
2-(3,5-Dioxothiomorpholino)-N-phenylacetamide
CAS 868215-00-3C12H12N2O3S
Ethyl 4-[[2-(3,5-dioxothiomorpholin-4-yl)acetyl]amino]benzoate chemical structure, C15H16N2O5S, CAS 868215-01-4
Ethyl 4-[[2-(3,5-dioxothiomorpholin-4-yl)acetyl]amino]benzoate
CAS 868215-01-4C15H16N2O5S
2-(3,5-Dioxothiomorpholin-4-yl)-N-(4-methoxyphenyl)acetamide chemical structure, C13H14N2O4S, CAS 868215-02-5
2-(3,5-Dioxothiomorpholin-4-yl)-N-(4-methoxyphenyl)acetamide
CAS 868215-02-5C13H14N2O4S
2-(3,5-Dioxothiomorpholin-4-yl)-N-(4-ethoxyphenyl)acetamide chemical structure, C14H16N2O4S, CAS 868215-05-8
2-(3,5-Dioxothiomorpholin-4-yl)-N-(4-ethoxyphenyl)acetamide
CAS 868215-05-8C14H16N2O4S
N-(2,3-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C14H16N2O3S, CAS 868215-06-9
N-(2,3-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-06-9C14H16N2O3S
N-(2,5-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C14H16N2O3S, CAS 868215-07-0
N-(2,5-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-07-0C14H16N2O3S
N-(2,4-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C14H16N2O3S, CAS 868215-08-1
N-(2,4-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-08-1C14H16N2O3S
N-(3,5-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C14H16N2O3S, CAS 868215-09-2
N-(3,5-Dimethylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-09-2C14H16N2O3S
N-(2,4-Dimethoxyphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C14H16N2O5S, CAS 868215-10-5
N-(2,4-Dimethoxyphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-10-5C14H16N2O5S
N-(4-Butylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C16H20N2O3S, CAS 868215-13-8
N-(4-Butylphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-13-8C16H20N2O3S
N-(5-Chloro-2-methoxyphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C13H13ClN2O4S, CAS 868215-15-0
N-(5-Chloro-2-methoxyphenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-15-0C13H13ClN2O4S
2-(3,5-Dioxothiomorpholin-4-yl)-N-(3-methoxyphenyl)acetamide chemical structure, C13H14N2O4S, CAS 868215-18-3
2-(3,5-Dioxothiomorpholin-4-yl)-N-(3-methoxyphenyl)acetamide
CAS 868215-18-3C13H14N2O4S
N-(3,4-Dichlorophenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C12H10Cl2N2O3S, CAS 868215-20-7
N-(3,4-Dichlorophenyl)-2-(3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-20-7C12H10Cl2N2O3S
2-(3,5-Dioxothiomorpholin-4-yl)-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C15H18N2O3S, CAS 868215-21-8
2-(3,5-Dioxothiomorpholin-4-yl)-N-(2,4,6-trimethylphenyl)acetamide
CAS 868215-21-8C15H18N2O3S
Ethyl 4-[[2-(2,6-diethyl-3,5-dioxothiomorpholin-4-yl)acetyl]amino]benzoate chemical structure, C19H24N2O5S, CAS 868215-62-7
Ethyl 4-[[2-(2,6-diethyl-3,5-dioxothiomorpholin-4-yl)acetyl]amino]benzoate
CAS 868215-62-7C19H24N2O5S
2-(2,6-Dimethyl-3,5-dioxothiomorpholin-4-yl)-N-(4-methylphenyl)acetamide chemical structure, C15H18N2O3S, CAS 868215-28-5
2-(2,6-Dimethyl-3,5-dioxothiomorpholin-4-yl)-N-(4-methylphenyl)acetamide
CAS 868215-28-5C15H18N2O3S
Ethyl 4-[[2-(2,6-dimethyl-3,5-dioxothiomorpholin-4-yl)acetyl]amino]benzoate chemical structure, C17H20N2O5S, CAS 868215-23-0
Ethyl 4-[[2-(2,6-dimethyl-3,5-dioxothiomorpholin-4-yl)acetyl]amino]benzoate
CAS 868215-23-0C17H20N2O5S
2-(2,6-Diethyl-3,5-dioxothiomorpholin-4-yl)-N-(2,4-dimethylphenyl)acetamide chemical structure, C18H24N2O3S, CAS 868215-68-3
2-(2,6-Diethyl-3,5-dioxothiomorpholin-4-yl)-N-(2,4-dimethylphenyl)acetamide
CAS 868215-68-3C18H24N2O3S
2-(2,6-Diethyl-3,5-dioxothiomorpholin-4-yl)-N-(3-methylphenyl)acetamide chemical structure, C17H22N2O3S, CAS 868215-64-9
2-(2,6-Diethyl-3,5-dioxothiomorpholin-4-yl)-N-(3-methylphenyl)acetamide
CAS 868215-64-9C17H22N2O3S
N-(3-Chlorophenyl)-2-(2,6-dimethyl-3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C14H15ClN2O3S, CAS 868215-46-7
N-(3-Chlorophenyl)-2-(2,6-dimethyl-3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-46-7C14H15ClN2O3S
2-(2,6-Dimethyl-3,5-dioxothiomorpholin-4-yl)-N-(2,4-dimethylphenyl)acetamide chemical structure, C16H20N2O3S, CAS 868215-33-2
2-(2,6-Dimethyl-3,5-dioxothiomorpholin-4-yl)-N-(2,4-dimethylphenyl)acetamide
CAS 868215-33-2C16H20N2O3S
2-(2,6-Dimethyl-3,5-dioxothiomorpholin-4-yl)-N-(3-methylphenyl)acetamide chemical structure, C15H18N2O3S, CAS 868215-29-6
2-(2,6-Dimethyl-3,5-dioxothiomorpholin-4-yl)-N-(3-methylphenyl)acetamide
CAS 868215-29-6C15H18N2O3S
2-(2,6-Diethyl-3,5-dioxothiomorpholin-4-yl)-N-(2,4-dimethoxyphenyl)acetamide chemical structure, C18H24N2O5S, CAS 868215-70-7
2-(2,6-Diethyl-3,5-dioxothiomorpholin-4-yl)-N-(2,4-dimethoxyphenyl)acetamide
CAS 868215-70-7C18H24N2O5S
N-(4-Chlorophenyl)-2-(2,6-dimethyl-3,5-dioxothiomorpholin-4-yl)acetamide chemical structure, C14H15ClN2O3S, CAS 868215-45-6
N-(4-Chlorophenyl)-2-(2,6-dimethyl-3,5-dioxothiomorpholin-4-yl)acetamide
CAS 868215-45-6C14H15ClN2O3S