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Murcko scaffold

Ring system with 4 rings and 26 atoms

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
16
With full pages
4
Scaffold SMILES

O=S(=O)(c1ccccc1)c1cnn(-c2ccccc2)c1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1cnn(-c2ccccc2)c1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

5-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl phenyl sulfone chemical structure, C21H15ClN2O2S, CAS 318951-61-0
5-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl phenyl sulfone
CAS 318951-61-0C21H15ClN2O2S
5-(4-Chlorophenyl)-1-(2,4-difluorophenyl)-4-(phenylsulfonyl)-1H-pyrazole chemical structure, C21H13ClF2N2O2S, CAS 318951-65-4
5-(4-Chlorophenyl)-1-(2,4-difluorophenyl)-4-(phenylsulfonyl)-1H-pyrazole
CAS 318951-65-4C21H13ClF2N2O2S
5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-4-(phenylsulfonyl)-1H-pyrazole chemical structure, C22H17ClN2O3S, CAS 318951-66-5
5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-4-(phenylsulfonyl)-1H-pyrazole
CAS 318951-66-5C22H17ClN2O3S
5-(4-Chlorophenyl)-1-(2,3-dimethylphenyl)-4-(phenylsulfonyl)-1H-pyrazole chemical structure, C23H19ClN2O2S, CAS 318951-68-7
5-(4-Chlorophenyl)-1-(2,3-dimethylphenyl)-4-(phenylsulfonyl)-1H-pyrazole
CAS 318951-68-7C23H19ClN2O2S
5-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl phenyl sulfone chemical structure, C22H18N2O3S, CAS 318951-69-8
5-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl phenyl sulfone
CAS 318951-69-8C22H18N2O3S
5-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl phenyl sulfone chemical structure, C21H15FN2O2S, CAS 318951-70-1
5-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl phenyl sulfone
CAS 318951-70-1C21H15FN2O2S
5-(3,4-Dichlorophenyl)-1-phenyl-4-(phenylsulfonyl)-1H-pyrazole chemical structure, C21H14Cl2N2O2S, CAS 318951-72-3
5-(3,4-Dichlorophenyl)-1-phenyl-4-(phenylsulfonyl)-1H-pyrazole
CAS 318951-72-3C21H14Cl2N2O2S
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole chemical structure, C22H12Cl3F3N2O2S, CAS 318951-63-2
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole
CAS 318951-63-2C22H12Cl3F3N2O2S
4-(Benzenesulfonyl)-1-(2,5-dichlorophenyl)-5-(4-fluorophenyl)pyrazole chemical structure, C21H13Cl2FN2O2S, CAS 318951-71-2
4-(Benzenesulfonyl)-1-(2,5-dichlorophenyl)-5-(4-fluorophenyl)pyrazole
CAS 318951-71-2C21H13Cl2FN2O2S
4-(Benzenesulfonyl)-5-(3,4-dichlorophenyl)-1-(4-fluorophenyl)pyrazole chemical structure, C21H13Cl2FN2O2S, CAS 318951-73-4
4-(Benzenesulfonyl)-5-(3,4-dichlorophenyl)-1-(4-fluorophenyl)pyrazole
CAS 318951-73-4C21H13Cl2FN2O2S
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)pyrazole chemical structure, C21H13Cl3N2O2S, CAS 318951-64-3
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)pyrazole
CAS 318951-64-3C21H13Cl3N2O2S
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)pyrazole chemical structure, C21H13Cl3N2O2S, CAS 318951-67-6
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)pyrazole
CAS 318951-67-6C21H13Cl3N2O2S
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-(2,3,4-trichlorophenyl)pyrazole chemical structure, C21H12Cl4N2O2S, CAS 318951-62-1
4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-(2,3,4-trichlorophenyl)pyrazole
CAS 318951-62-1C21H12Cl4N2O2S
1H-Pyrazole, 3-methyl-1-(4-nitrophenyl)-5-phenyl-4-(phenylsulfonyl)- chemical structure, C22H17N3O4S, CAS 61261-97-0
1H-Pyrazole, 3-methyl-1-(4-nitrophenyl)-5-phenyl-4-(phenylsulfonyl)-
CAS 61261-97-0C22H17N3O4S
1H-Pyrazole, 3-ethyl-1-(4-nitrophenyl)-5-phenyl-4-(phenylsulfonyl)- chemical structure, C23H19N3O4S, CAS 61261-98-1
1H-Pyrazole, 3-ethyl-1-(4-nitrophenyl)-5-phenyl-4-(phenylsulfonyl)-
CAS 61261-98-1C23H19N3O4S
1H-Pyrazole, 1-(4-nitrophenyl)-5-phenyl-4-(phenylsulfonyl)-3-propyl- chemical structure, C24H21N3O4S, CAS 61261-99-2
1H-Pyrazole, 1-(4-nitrophenyl)-5-phenyl-4-(phenylsulfonyl)-3-propyl-
CAS 61261-99-2C24H21N3O4S