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Murcko scaffold

Ring system with 3 rings and 17 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
9
With full pages
2
Scaffold SMILES

O=c1cc(-c2ccccc2)c2cccnc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(-c2ccccc2)c2cccnc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

4-(4-Fluorophenyl)-1,5,7-trimethyl-2-oxo-1,8-naphthyridine-3-carbonitrile chemical structure, C18H14FN3O, CAS 745035-75-0
4-(4-Fluorophenyl)-1,5,7-trimethyl-2-oxo-1,8-naphthyridine-3-carbonitrile
CAS 745035-75-0C18H14FN3O
7-Amino-4-(3-nitrophenyl)-1H-1,8-naphthyridin-2-one chemical structure, C14H10N4O3, CAS 53734-89-7
7-Amino-4-(3-nitrophenyl)-1H-1,8-naphthyridin-2-one
CAS 53734-89-7C14H10N4O3
7-Amino-4-(4-nitrophenyl)-1,8-naphthyridin-2(1H)-one chemical structure, C14H10N4O3, CAS 53734-90-0
7-Amino-4-(4-nitrophenyl)-1,8-naphthyridin-2(1H)-one
CAS 53734-90-0C14H10N4O3
1,8-Naphthyridin-2(1H)-one, 3-amino-1-butyl-4-(3-hydroxyphenyl)- chemical structure, C18H19N3O2, CAS 501690-38-6
1,8-Naphthyridin-2(1H)-one, 3-amino-1-butyl-4-(3-hydroxyphenyl)-
CAS 501690-38-6C18H19N3O2
Asp-3258 chemical structure, C20H19ClN2O3, CAS 337357-62-7
Asp-3258
CAS 337357-62-7C20H19ClN2O3
4-(p-Tolyl)-1,8-naphthyridin-2(1H)-one chemical structure, C15H12N2O, CAS 127446-47-3
4-(p-Tolyl)-1,8-naphthyridin-2(1H)-one
CAS 127446-47-3C15H12N2O
1-Hydroxy-4-(3-hydroxyphenyl)-1,8-naphthyridin-2(1H)-one chemical structure, C14H10N2O3, CAS 1003930-43-5
1-Hydroxy-4-(3-hydroxyphenyl)-1,8-naphthyridin-2(1H)-one
CAS 1003930-43-5C14H10N2O3
tert-Butyl 5-chloro-2-oxo-4-phenyl-1H-1,8-naphthyridine-3-carboxylate chemical structure, C19H17ClN2O3, CAS 1203510-06-8
tert-Butyl 5-chloro-2-oxo-4-phenyl-1H-1,8-naphthyridine-3-carboxylate
CAS 1203510-06-8C19H17ClN2O3
5-Chloro-1,2-dihydro-2-oxo-4-phenyl-1,8-naphthyridine-3-carboxylic acid chemical structure, C15H9ClN2O3, CAS 1309863-29-3
5-Chloro-1,2-dihydro-2-oxo-4-phenyl-1,8-naphthyridine-3-carboxylic acid
CAS 1309863-29-3C15H9ClN2O3