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Murcko scaffold

4-Hydroxypyrido (2,3-d)pyrimidine scaffold

110 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 110
With full pages: 9

Scaffold SMILES

O=c1ncnc2[nH]cccc1-2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 4-Hydroxypyrido (2,3-d)pyrimidine page

Murcko scaffold O=c1ncnc2[nH]cccc1-2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 110 chemicals

6,8-Dimethyl-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-4(8H)-one chemical structure, C10H11N3OS, CAS 64600-57-3

6,8-Dimethyl-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-4(8H)-one

CAS 64600-57-3C₁₀H₁₁N₃OS

Pyrido(2,3-d)pyrimidin-4(3H)-one, 3-(2-(diethylamino)ethyl)-2-methyl- chemical structure, C14H20N4O, CAS 101204-95-9

Pyrido(2,3-d)pyrimidin-4(3H)-one, 3-(2-(diethylamino)ethyl)-2-methyl-

CAS 101204-95-9C₁₄H₂₀N₄O

Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 3,4-dihydro-3,7-dimethyl-4-oxo-2-(2-propenylthio)-,ethyl ester chemical structure, C15H17N3O3S, CAS 126596-45-0

Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 3,4-dihydro-3,7-dimethyl-4-oxo-2-(2-propenylthio)-,ethyl ester

CAS 126596-45-0C₁₅H₁₇N₃O₃S

2-Amino-8-ethyl-6-methylpyrido[2,3-d]pyrimidin-4(8H)-one chemical structure, C10H12N4O, CAS 753422-57-0

2-Amino-8-ethyl-6-methylpyrido[2,3-d]pyrimidin-4(8H)-one

CAS 753422-57-0C₁₀H₁₂N₄O

2-Amino-6-methyl-8-propylpyrido[2,3-d]pyrimidin-4(8H)-one chemical structure, C11H14N4O, CAS 786614-49-1

2-Amino-6-methyl-8-propylpyrido[2,3-d]pyrimidin-4(8H)-one

CAS 786614-49-1C₁₁H₁₄N₄O

6-Bromo-2-propoxy-3-propylpyrido[2,3-d]pyrimidin-4(3H)-one chemical structure, C13H16BrN3O2, CAS 187538-01-8

6-Bromo-2-propoxy-3-propylpyrido[2,3-d]pyrimidin-4(3H)-one

CAS 187538-01-8C₁₃H₁₆BrN₃O₂

1-Ethyl-2-hydrazino-5,7-dimethylpyrido[2,3-D]pyrimidin-4(1H)-one chemical structure, C11H15N5O, CAS 937600-42-5

1-Ethyl-2-hydrazino-5,7-dimethylpyrido[2,3-D]pyrimidin-4(1H)-one

CAS 937600-42-5C₁₁H₁₅N₅O

2-Hydrazinyl-1-(2-methoxyethyl)-5,7-dimethylpyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C12H17N5O2, CAS 937600-45-8

2-Hydrazinyl-1-(2-methoxyethyl)-5,7-dimethylpyrido[2,3-d]pyrimidin-4(1H)-one

CAS 937600-45-8C₁₂H₁₇N₅O₂

Ethyl 2-((1-ethyl-5,7-dimethyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidin-2-yl)thio)acetate chemical structure, C15H19N3O3S, CAS 937599-92-3

Ethyl 2-((1-ethyl-5,7-dimethyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidin-2-yl)thio)acetate

CAS 937599-92-3C₁₅H₁₉N₃O₃S

2-Hydrazinyl-1,5,7-trimethylpyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C10H13N5O, CAS 937601-62-2

2-Hydrazinyl-1,5,7-trimethylpyrido[2,3-d]pyrimidin-4(1H)-one

CAS 937601-62-2C₁₀H₁₃N₅O

Pyrido(2,3-d)pyrimidin-4(3H)-one, 3-(2-(diethylamino)ethyl)- chemical structure, C13H18N4O, CAS 88350-73-6

Pyrido(2,3-d)pyrimidin-4(3H)-one, 3-(2-(diethylamino)ethyl)-

CAS 88350-73-6C₁₃H₁₈N₄O

2-(4-Oxopyrido[2,3-d]pyrimidin-3(4H)-yl)acetic acid chemical structure, C9H7N3O3, CAS 1105192-07-1

2-(4-Oxopyrido[2,3-d]pyrimidin-3(4H)-yl)acetic acid

CAS 1105192-07-1C₉H₇N₃O₃

2-Amino-8-methyl-4-oxo-4,8-dihydropyrido[2,3-d]pyrimidine-6-carbaldehyde chemical structure, C9H8N4O2, CAS 785019-42-3

2-Amino-8-methyl-4-oxo-4,8-dihydropyrido[2,3-d]pyrimidine-6-carbaldehyde

CAS 785019-42-3C₉H₈N₄O₂

2-Methyl-N-[2-(2-methyl-4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl)ethyl]propanamide chemical structure, C14H18N4O2, CAS 1574408-82-4

2-Methyl-N-[2-(2-methyl-4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl)ethyl]propanamide

CAS 1574408-82-4C₁₄H₁₈N₄O₂

3-(2-Aminoethyl)pyrido[2,3-d]pyrimidin-4(3H)-one chemical structure, C9H10N4O, CAS 1510638-86-4

3-(2-Aminoethyl)pyrido[2,3-d]pyrimidin-4(3H)-one

CAS 1510638-86-4C₉H₁₀N₄O

2-(4-Oxopyrido[2,3-d]pyrimidin-3(4H)-yl)acetic acid hydrochloride chemical structure, C9H8ClN3O3, CAS 1820666-53-2

2-(4-Oxopyrido[2,3-d]pyrimidin-3(4H)-yl)acetic acid hydrochloride

CAS 1820666-53-2C₉H₈ClN₃O₃

3-(3-Methyl-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)propanoic acid chemical structure, C11H11N3O3, CAS 1713639-30-5

3-(3-Methyl-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)propanoic acid

CAS 1713639-30-5C₁₁H₁₁N₃O₃

3-(3-Ethyl-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)propanoic acid chemical structure, C12H13N3O3, CAS 1707394-38-4

3-(3-Ethyl-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)propanoic acid

CAS 1707394-38-4C₁₂H₁₃N₃O₃

7-Methoxy-5-methyl-4-oxopyrido[2,3-d]pyrimidine-3(4H)-acetic acid chemical structure, C11H11N3O4, CAS 1817727-61-9

7-Methoxy-5-methyl-4-oxopyrido[2,3-d]pyrimidine-3(4H)-acetic acid

CAS 1817727-61-9C₁₁H₁₁N₃O₄

Ethyl 2-(4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl)acetate chemical structure, C11H11N3O3, CAS 2034455-42-8

Ethyl 2-(4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl)acetate

CAS 2034455-42-8C₁₁H₁₁N₃O₃

2-Amino-6,7-dimethylpyrido[2,3-d]pyrimidin-4-ol chemical structure, C9H10N4O, CAS 6327-15-7

2-Amino-6,7-dimethylpyrido[2,3-d]pyrimidin-4-ol

CAS 6327-15-7C₉H₁₀N₄O

2-Aminopyrido(2,3-d)pyrimidin-4(3H)-one chemical structure, C7H6N4O, CAS 7255-87-0

2-Aminopyrido(2,3-d)pyrimidin-4(3H)-one

CAS 7255-87-0C₇H₆N₄O

5,7-Dimethylpyrido[2,3-d]pyrimidin-4(3H)-one chemical structure, C9H9N3O, CAS 1913-72-0

5,7-Dimethylpyrido[2,3-d]pyrimidin-4(3H)-one

CAS 1913-72-0C₉H₉N₃O

(4-Hydroxy-5,7-dimethyl-pyrido[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid chemical structure, C11H11N3O3S, CAS 443749-00-6

(4-Hydroxy-5,7-dimethyl-pyrido[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid

CAS 443749-00-6C₁₁H₁₁N₃O₃S