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Murcko scaffold

Acetamide, N-phenyl-2-(phenylsulfonyl)- scaffold

97 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
97
With full pages
21
Scaffold SMILES

O=C(CS(=O)(=O)c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Acetamide, N-phenyl-2-(phenylsulfonyl)- page
Murcko scaffold O=C(CS(=O)(=O)c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 97 chemicals

N-(2,5-Dimethoxyphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C16H17NO5S, CAS 674808-00-5
N-(2,5-Dimethoxyphenyl)-2-(phenylsulfonyl)acetamide
CAS 674808-00-5C16H17NO5S
N-(4-Chlorophenyl)-2-(phenylsulfonyl)acetamide chemical structure, C14H12ClNO3S, CAS 54306-33-1
N-(4-Chlorophenyl)-2-(phenylsulfonyl)acetamide
CAS 54306-33-1C14H12ClNO3S
N-(3-Chloro-2-methylphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C15H14ClNO3S, CAS 523991-80-2
N-(3-Chloro-2-methylphenyl)-2-(phenylsulfonyl)acetamide
CAS 523991-80-2C15H14ClNO3S
N-(3,5-Dimethylphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C16H17NO3S, CAS 675142-16-2
N-(3,5-Dimethylphenyl)-2-(phenylsulfonyl)acetamide
CAS 675142-16-2C16H17NO3S
N-(4-Methoxyphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C15H15NO4S, CAS 54306-34-2
N-(4-Methoxyphenyl)-2-(phenylsulfonyl)acetamide
CAS 54306-34-2C15H15NO4S
N-(3-Acetylphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C16H15NO4S, CAS 712320-02-0
N-(3-Acetylphenyl)-2-(phenylsulfonyl)acetamide
CAS 712320-02-0C16H15NO4S
N-(2-Methoxy-5-methylphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C16H17NO4S, CAS 712320-03-1
N-(2-Methoxy-5-methylphenyl)-2-(phenylsulfonyl)acetamide
CAS 712320-03-1C16H17NO4S
N-(3,4-Dichlorophenyl)-2-(phenylsulfonyl)acetamide chemical structure, C14H11Cl2NO3S, CAS 712320-04-2
N-(3,4-Dichlorophenyl)-2-(phenylsulfonyl)acetamide
CAS 712320-04-2C14H11Cl2NO3S
2-(Phenylsulfonyl)-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C15H12F3NO3S, CAS 712320-05-3
2-(Phenylsulfonyl)-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 712320-05-3C15H12F3NO3S
2-(Benzenesulfonyl)-N-(2-bromophenyl)acetamide chemical structure, C14H12BrNO3S, CAS 794550-80-4
2-(Benzenesulfonyl)-N-(2-bromophenyl)acetamide
CAS 794550-80-4C14H12BrNO3S
N-(5-Chloro-2,4-dimethoxyphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C16H16ClNO5S, CAS 823825-82-7
N-(5-Chloro-2,4-dimethoxyphenyl)-2-(phenylsulfonyl)acetamide
CAS 823825-82-7C16H16ClNO5S
2-(Phenylsulfonyl)-N-(3,4,5-trimethoxyphenyl)acetamide chemical structure, C17H19NO6S, CAS 823825-84-9
2-(Phenylsulfonyl)-N-(3,4,5-trimethoxyphenyl)acetamide
CAS 823825-84-9C17H19NO6S
2-(Benzenesulfonyl)-N-(4-iodophenyl)acetamide chemical structure, C14H12INO3S, CAS 270065-33-3
2-(Benzenesulfonyl)-N-(4-iodophenyl)acetamide
CAS 270065-33-3C14H12INO3S
N-(2-Hydroxyphenyl)-2-(phenylsulfonyl)acetamide chemical structure, C14H13NO4S, CAS 823825-86-1
N-(2-Hydroxyphenyl)-2-(phenylsulfonyl)acetamide
CAS 823825-86-1C14H13NO4S
N-(2-Methoxy-5-nitrophenyl)-2-(4-methylphenyl)sulfonylacetamide chemical structure, C16H16N2O6S, CAS 826999-10-4
N-(2-Methoxy-5-nitrophenyl)-2-(4-methylphenyl)sulfonylacetamide
CAS 826999-10-4C16H16N2O6S
2-[(4-Methylphenyl)sulfonyl]-N-(3,4,5-trimethoxyphenyl)acetamide chemical structure, C18H21NO6S, CAS 827003-62-3
2-[(4-Methylphenyl)sulfonyl]-N-(3,4,5-trimethoxyphenyl)acetamide
CAS 827003-62-3C18H21NO6S
2-[(3-Chlorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide chemical structure, C15H14ClNO4S, CAS 339097-23-3
2-[(3-Chlorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide
CAS 339097-23-3C15H14ClNO4S
2-[(4-Fluorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide chemical structure, C15H14FNO4S, CAS 339097-29-9
2-[(4-Fluorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide
CAS 339097-29-9C15H14FNO4S
2-[(2-Chlorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide chemical structure, C15H14ClNO4S, CAS 339097-37-9
2-[(2-Chlorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide
CAS 339097-37-9C15H14ClNO4S
2-[(3,4-Dichlorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide chemical structure, C15H13Cl2NO4S, CAS 339097-39-1
2-[(3,4-Dichlorophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide
CAS 339097-39-1C15H13Cl2NO4S
N-(4-Methoxyphenyl)-2-{[3-(trifluoromethyl)phenyl]sulfonyl}acetamide chemical structure, C16H14F3NO4S, CAS 339097-47-1
N-(4-Methoxyphenyl)-2-{[3-(trifluoromethyl)phenyl]sulfonyl}acetamide
CAS 339097-47-1C16H14F3NO4S
2-[(4-Bromophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide chemical structure, C15H14BrNO4S, CAS 339097-51-7
2-[(4-Bromophenyl)sulfonyl]-N-(4-methoxyphenyl)acetamide
CAS 339097-51-7C15H14BrNO4S
2-[(4-Methoxyphenyl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C16H14F3NO4S, CAS 339107-29-8
2-[(4-Methoxyphenyl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 339107-29-8C16H14F3NO4S
2-[(3-Chlorophenyl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C15H11ClF3NO3S, CAS 339107-31-2
2-[(3-Chlorophenyl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 339107-31-2C15H11ClF3NO3S