Murcko scaffold
Hexahydrocyclopenta(c)pyrrol-5(1H)-one scaffold
35 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 35
- With full pages
- 3
Scaffold SMILES
O=C1CC2CNCC2C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 35 of 35 chemicals
![2-Acetylhexahydrocyclopenta[c]pyrrol-5(1H)-one chemical structure, C9H13NO2, CAS 129222-15-7](/s/PYYIZEKRAHOYCN-UHFFFAOYSA-N.svg)
2-Acetylhexahydrocyclopenta[c]pyrrol-5(1H)-one
CAS 129222-15-7C9H13NO2
tert-Butyl 5-oxohexahydrocyclopenta(c)pyrrole-2(1H)-carboxylate
CAS 148404-28-8C12H19NO3
![cis-tert-Butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate chemical structure, C12H19NO3, CAS 146231-54-1](/s/GGNDIMLSSMWKDR-DTORHVGOSA-N.svg)
cis-tert-Butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
CAS 146231-54-1C12H19NO3
![cis-2-(2,2,2-Trifluoroacetyl)hexahydrocyclopenta[c]pyrrol-5(1H)-one chemical structure, C9H10F3NO2, CAS 445389-16-2](/s/ISBFCMOGUHRWRM-OLQVQODUSA-N.svg)
cis-2-(2,2,2-Trifluoroacetyl)hexahydrocyclopenta[c]pyrrol-5(1H)-one
CAS 445389-16-2C9H10F3NO2
Pyyizekrahoycn-ocaptikfsa-
CAS 445389-15-1C9H13NO2
Hexahydrocyclopenta(c)pyrrol-5(1H)-one
CAS 1257389-95-9C7H11NO
![2-(2,2,2-Trifluoroacetyl)hexahydrocyclopenta[c]pyrrol-5(1H)-one chemical structure, C9H10F3NO2, CAS 1263280-07-4](/s/ISBFCMOGUHRWRM-UHFFFAOYSA-N.svg)
2-(2,2,2-Trifluoroacetyl)hexahydrocyclopenta[c]pyrrol-5(1H)-one
CAS 1263280-07-4C9H10F3NO2
![cis-4-Methyl-2,3,3a,4,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-one chemical structure, C8H13NO, CAS 687966-31-0](/s/SKBDFQUCXXTWRC-JXBXZBNISA-N.svg)
cis-4-Methyl-2,3,3a,4,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-one
CAS 687966-31-0C8H13NO
![2-Methyl-octahydrocyclopenta[c]pyrrol-5-one chemical structure, C8H13NO, CAS 1540635-33-3](/s/HKVSBWUHJDYRGQ-UHFFFAOYSA-N.svg)
2-Methyl-octahydrocyclopenta[c]pyrrol-5-one
CAS 1540635-33-3C8H13NO
![N,N-Dimethyl-5-oxo-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide chemical structure, C10H16N2O2, CAS 1042666-57-8](/s/GTDBSXAQZGPRFO-UHFFFAOYSA-N.svg)
N,N-Dimethyl-5-oxo-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide
CAS 1042666-57-8C10H16N2O2
![5-Oxo-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid ethyl ester chemical structure, C10H15NO3, CAS 879688-10-5](/s/DIEGYGAAARSLDF-UHFFFAOYSA-N.svg)
5-Oxo-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid ethyl ester
CAS 879688-10-5C10H15NO3
![tert-Butyl 4-methyl-5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate chemical structure, C13H21NO3, CAS 148404-30-2](/s/LVNPZCBWMQZMNC-UHFFFAOYSA-N.svg)
tert-Butyl 4-methyl-5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
CAS 148404-30-2C13H21NO3
![tert-Butyl (3aS,6aR)-3a-methyl-5-oxo-3,4,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carboxylate chemical structure, C13H21NO3, CAS 2649804-28-2](/s/XOEPWIVMAMTUIJ-TVQRCGJNSA-N.svg)
tert-Butyl (3aS,6aR)-3a-methyl-5-oxo-3,4,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carboxylate
CAS 2649804-28-2C13H21NO3
![Hexahydrocyclopenta[c]pyrrol-5(1H)-one hydrochloride chemical structure, C7H12ClNO, CAS 1263378-05-7](/s/VXGNCPOILAXTAM-UHFFFAOYSA-N.svg)
Hexahydrocyclopenta[c]pyrrol-5(1H)-one hydrochloride
CAS 1263378-05-7C7H12ClNO
![2-Boc-5-oxo-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid chemical structure, C13H19NO5, CAS 1419100-98-3](/s/KMDJCCBSGFKRFR-UHFFFAOYSA-N.svg)
2-Boc-5-oxo-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid
CAS 1419100-98-3C13H19NO5
![5-Oxo-octahydro-cyclopenta[c]-pyrrole-1-carboxylic acid chemical structure, C8H11NO3, CAS 1403766-56-2](/s/GYVMVZUBLHDJPJ-UHFFFAOYSA-N.svg)
5-Oxo-octahydro-cyclopenta[c]-pyrrole-1-carboxylic acid
CAS 1403766-56-2C8H11NO3
![4-Methylhexahydrocyclopenta[c]pyrrol-5(1H)-one chemical structure, C8H13NO, CAS 1824190-34-2](/s/SKBDFQUCXXTWRC-UHFFFAOYSA-N.svg)
4-Methylhexahydrocyclopenta[c]pyrrol-5(1H)-one
CAS 1824190-34-2C8H13NO
![tert-Butyl trans-5-oxo-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxylate chemical structure, C12H19NO3, CAS 2940875-46-5](/s/GGNDIMLSSMWKDR-RKDXNWHRSA-N.svg)
tert-Butyl trans-5-oxo-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxylate
CAS 2940875-46-5C12H19NO3
![rac-tert-Butyl (3aR,6aR)-5-oxo-octahydrocyclopenta[c]pyrrole-2-carboxylate chemical structure, C12H19NO3, CAS 2382413-71-8](/s/GGNDIMLSSMWKDR-IUCAKERBSA-N.svg)
rac-tert-Butyl (3aR,6aR)-5-oxo-octahydrocyclopenta[c]pyrrole-2-carboxylate
CAS 2382413-71-8C12H19NO3
![rac-(3aR,6aR)-octahydrocyclopenta[c]pyrrol-5-one chemical structure, C7H11NO, CAS 2705319-36-2](/s/XRSFPEFHACEZSM-PHDIDXHHSA-N.svg)
rac-(3aR,6aR)-octahydrocyclopenta[c]pyrrol-5-one
CAS 2705319-36-2C7H11NO
![cis-Octahydrocyclopenta[c]pyrrol-5-one hydrochloride chemical structure, C7H12ClNO, CAS 1872371-83-9](/s/VXGNCPOILAXTAM-KNCHESJLSA-N.svg)
cis-Octahydrocyclopenta[c]pyrrol-5-one hydrochloride
CAS 1872371-83-9C7H12ClNO
![tert-Butyl (3aR,6aS)-3a-methyl-5-oxo-3,4,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carboxylate chemical structure, C13H21NO3, CAS 2649804-27-1](/s/XOEPWIVMAMTUIJ-RNCFNFMXSA-N.svg)
tert-Butyl (3aR,6aS)-3a-methyl-5-oxo-3,4,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carboxylate
CAS 2649804-27-1C13H21NO3
2-tert-Butyl 4-methyl 5-oxo-octahydrocyclopenta(c)pyrrole-2,4-dicarboxylate
CAS 1369496-58-1C14H21NO5
![Rel-(3aR,6aR)-4-methylhexahydrocyclopenta[c]pyrrol-5(1H)-one hydrochloride chemical structure, C8H14ClNO](/s/KIUZMIXAXQDUQF-LVCWUQNBSA-N.svg)
Rel-(3aR,6aR)-4-methylhexahydrocyclopenta[c]pyrrol-5(1H)-one hydrochloride
C8H14ClNO
- Rel-(3aR,6aR)-4-methylhexahydrocyclopenta[c]pyrrol-5(1H)-oneC8H13NO
- Methyl 5-oxo-octahydrocyclopenta[c]pyrrole-4-carboxylate2680869-85-4C9H13NO3
- tert-Butyl rel-(3aR,4R,6aS)-4-fluoro-5-oxo-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxylate2649804-11-3C12H18FNO3
- trans-2,3,3a,4,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-5-one, hydrochloride2940869-79-2C7H12ClNO
- (3aR,6aS)-Octahydrocyclopenta[c]pyrrol-5-one2449057-88-7C14H22N2O2
- cis-Hexahydro-cyclopenta[c]pyrrol-5(1H)-one HClC14H24Cl2N2O2
- (3aS,6aS)-4-Methylhexahydrocyclopenta[c]pyrrol-5(1H)-one hydrochloride1469-45-0C8H14ClNO
- tert-Butyl rel-(3aR,4S,6aS)-4-fluoro-5-oxo-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxylate2649804-12-4C12H18FNO3
- tert-Butyl 3a-fluoro-5-oxo-3,4,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carboxylate2169601-47-0C12H18FNO3
- tert-Butyl (3aR,6aS)-3a-fluoro-5-oxo-3,4,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carboxylate2165928-45-8C12H18FNO3
- rel-tert-Butyl (3aS,6aR)-3a-fluoro-5-oxo-3,4,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carboxylate1290626-78-6C12H18FNO3
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