CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 12 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
13
With full pages
6
Scaffold SMILES

O=C1CC=NN1c1ncccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC=NN1c1ncccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

3-(tert-Butyl)-1-(4,6-dimethylpyrimidin-2-yl)-2-pyrazolin-5-one chemical structure, C13H18N4O, CAS 775292-20-1
3-(tert-Butyl)-1-(4,6-dimethylpyrimidin-2-yl)-2-pyrazolin-5-one
CAS 775292-20-1C13H18N4O
Methyl [1-(4,6-dimethylpyrimidin-2-yl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetate chemical structure, C12H14N4O3, CAS 774562-27-5
Methyl [1-(4,6-dimethylpyrimidin-2-yl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetate
CAS 774562-27-5C12H14N4O3
2-(4,6-Dimethylpyrimidin-2-yl)-4,5-dimethyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C11H14N4O, CAS 876667-41-3
2-(4,6-Dimethylpyrimidin-2-yl)-4,5-dimethyl-2,4-dihydro-3H-pyrazol-3-one
CAS 876667-41-3C11H14N4O
2-(4,6-Dimethylpyrimidin-2-yl)-5-methyl-4-(3-methylbutyl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C15H22N4O, CAS 726199-00-4
2-(4,6-Dimethylpyrimidin-2-yl)-5-methyl-4-(3-methylbutyl)-2,4-dihydro-3H-pyrazol-3-one
CAS 726199-00-4C15H22N4O
2-(4,6-Dimethylpyrimidin-2-yl)-5-propyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C12H16N4O, CAS 726198-95-4
2-(4,6-Dimethylpyrimidin-2-yl)-5-propyl-2,4-dihydro-3H-pyrazol-3-one
CAS 726198-95-4C12H16N4O
2-(4,6-Dimethylpyrimidin-2-yl)-4-ethyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C12H16N4O, CAS 726198-98-7
2-(4,6-Dimethylpyrimidin-2-yl)-4-ethyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one
CAS 726198-98-7C12H16N4O
2-(4,6-Dimethylpyrimidin-2-yl)-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C10H9F3N4O, CAS 775292-21-2
2-(4,6-Dimethylpyrimidin-2-yl)-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one
CAS 775292-21-2C10H9F3N4O
4-Butyl-2-(4,6-dimethylpyrimidin-2-yl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C14H20N4O, CAS 879621-81-5
4-Butyl-2-(4,6-dimethylpyrimidin-2-yl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
CAS 879621-81-5C14H20N4O
2-(4,6-Dimethylpyrimidin-2-yl)-5-(propan-2-yl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C12H16N4O, CAS 879567-59-6
2-(4,6-Dimethylpyrimidin-2-yl)-5-(propan-2-yl)-2,4-dihydro-3H-pyrazol-3-one
CAS 879567-59-6C12H16N4O
2-(4,6-Dimethylpyrimidin-2-yl)-5-methyl-4-propyl-4H-pyrazol-3-one chemical structure, C13H18N4O, CAS 879624-59-6
2-(4,6-Dimethylpyrimidin-2-yl)-5-methyl-4-propyl-4H-pyrazol-3-one
CAS 879624-59-6C13H18N4O
1-(4,6-Dimethylpyrimidin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C10H12N4O, CAS 99069-52-0
1-(4,6-Dimethylpyrimidin-2-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one
CAS 99069-52-0C10H12N4O
3-Amino-1-(4,6-dimethylpyrimidin-2-yl)-1H-pyrazol-5(4H)-one chemical structure, C9H11N5O, CAS 1306738-47-5
3-Amino-1-(4,6-dimethylpyrimidin-2-yl)-1H-pyrazol-5(4H)-one
CAS 1306738-47-5C9H11N5O
4,5-Dimethyl-2-pyrimidin-2-yl-4H-pyrazol-3-one chemical structure, C9H10N4O, CAS 1184800-46-1
4,5-Dimethyl-2-pyrimidin-2-yl-4H-pyrazol-3-one
CAS 1184800-46-1C9H10N4O