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Murcko scaffold

4-(4-Benzoylpiperazin-1-yl)quinoline scaffold

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
7
With full pages
3
Scaffold SMILES

O=C(c1ccccc1)N1CCN(c2ccnc3ccccc23)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(4-Benzoylpiperazin-1-yl)quinoline page
Murcko scaffold O=C(c1ccccc1)N1CCN(c2ccnc3ccccc23)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

(4-Chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanone chemical structure, C20H17Cl2N3O, CAS 337328-21-9
(4-Chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanone
CAS 337328-21-9C20H17Cl2N3O
[4-(7-Chloroquinolin-4-yl)piperazin-1-yl](4-fluorophenyl)methanone chemical structure, C20H17ClFN3O, CAS 774551-32-5
[4-(7-Chloroquinolin-4-yl)piperazin-1-yl](4-fluorophenyl)methanone
CAS 774551-32-5C20H17ClFN3O
7-Chloro-4-[4-(4-methylbenzoyl)piperazin-1-yl]quinoline chemical structure, C21H20ClN3O, CAS 337328-42-4
7-Chloro-4-[4-(4-methylbenzoyl)piperazin-1-yl]quinoline
CAS 337328-42-4C21H20ClN3O
(3-Chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanone chemical structure, C20H17Cl2N3O, CAS 696616-49-6
(3-Chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanone
CAS 696616-49-6C20H17Cl2N3O
4-(4-Benzoylpiperazin-1-yl)-7-chloroquinoline chemical structure, C20H18ClN3O, CAS 161467-85-2
4-(4-Benzoylpiperazin-1-yl)-7-chloroquinoline
CAS 161467-85-2C20H18ClN3O
[4-(7-Chloroquinolin-4-yl)piperazin-1-yl]-(2-fluorophenyl)methanone chemical structure, C20H17ClFN3O, CAS 337329-05-2
[4-(7-Chloroquinolin-4-yl)piperazin-1-yl]-(2-fluorophenyl)methanone
CAS 337329-05-2C20H17ClFN3O
4-(4-Benzoylpiperazin-1-yl)quinoline chemical structure, C20H19N3O, CAS 2741899-98-7
4-(4-Benzoylpiperazin-1-yl)quinoline
CAS 2741899-98-7C20H19N3O