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Murcko scaffold

4-Cyclopropylbiphenyl scaffold

134 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
134
With full pages
3
Scaffold SMILES

c1ccc(-c2ccc(C3CC3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Cyclopropylbiphenyl page
Murcko scaffold c1ccc(-c2ccc(C3CC3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 134 chemicals

4-Cyclopropylbiphenyl chemical structure, C15H14, CAS 35076-77-8
4-Cyclopropylbiphenyl
CAS 35076-77-8C15H14
Chf-5074 chemical structure, C16H11Cl2FO2, CAS 749269-83-8
Chf-5074
CAS 749269-83-8C16H11Cl2FO2
Chf-5022 chemical structure, C17H12F4O2, CAS 749269-77-0
Chf-5022
CAS 749269-77-0C17H12F4O2
1-[4-[3-(Trifluoromethyl)phenyl]phenyl]cyclopropane-1-carboxylic acid chemical structure, C17H13F3O2, CAS 877607-28-8
1-[4-[3-(Trifluoromethyl)phenyl]phenyl]cyclopropane-1-carboxylic acid
CAS 877607-28-8C17H13F3O2
1-(2-Fluoro-4'-hydroxy-biphenyl-4-yl)-cyclopropanecarboxylic acid chemical structure, C16H13FO3, CAS 749269-80-5
1-(2-Fluoro-4'-hydroxy-biphenyl-4-yl)-cyclopropanecarboxylic acid
CAS 749269-80-5C16H13FO3
1-[4-[3,5-Bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid chemical structure, C16H11Cl2FO2, CAS 876625-29-5
1-[4-[3,5-Bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid
CAS 876625-29-5C16H11Cl2FO2
Ethyl (1R,2R)-2-(4-Biphenylyl)cyclopropanecarboxylate chemical structure, C18H18O2, CAS 1052650-67-5
Ethyl (1R,2R)-2-(4-Biphenylyl)cyclopropanecarboxylate
CAS 1052650-67-5C18H18O2
1-(4-Biphenylyl)cyclopropanamine chemical structure, C15H15N, CAS 1266177-68-7
1-(4-Biphenylyl)cyclopropanamine
CAS 1266177-68-7C15H15N
rac-(1R,2R)-2-(4-Phenylphenyl)cyclopropane-1-carboxylic acid chemical structure, C16H14O2, CAS 27553-04-4
rac-(1R,2R)-2-(4-Phenylphenyl)cyclopropane-1-carboxylic acid
CAS 27553-04-4C16H14O2
2-(4-Phenylphenyl)cyclopropan-1-amine chemical structure, C15H15N, CAS 1157140-28-7
2-(4-Phenylphenyl)cyclopropan-1-amine
CAS 1157140-28-7C15H15N
2-(4-Phenylphenyl)cyclopropane-1-carboxylic acid chemical structure, C16H14O2, CAS 1157562-54-3
2-(4-Phenylphenyl)cyclopropane-1-carboxylic acid
CAS 1157562-54-3C16H14O2
1-(4-Biphenylyl)cyclopropanecarboxylic acid chemical structure, C16H14O2, CAS 93022-07-2
1-(4-Biphenylyl)cyclopropanecarboxylic acid
CAS 93022-07-2C16H14O2
Ethyl 2-(4-phenylphenyl)cyclopropane-1-carboxylate chemical structure, C18H18O2, CAS 1052650-70-0
Ethyl 2-(4-phenylphenyl)cyclopropane-1-carboxylate
CAS 1052650-70-0C18H18O2
3-[4-(2-Aminocyclopropyl)phenyl]phenol chemical structure, C15H15NO, CAS 1332859-11-6
3-[4-(2-Aminocyclopropyl)phenyl]phenol
CAS 1332859-11-6C15H15NO
OG-L002 chemical structure, C15H15NO, CAS 1357302-64-7
OG-L002
CAS 1357302-64-7C15H15NO
4'-((1S,2R)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol hydrochloride chemical structure, C15H16ClNO, CAS 1357299-46-7
4'-((1S,2R)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol hydrochloride
CAS 1357299-46-7C15H16ClNO
4'-((1S,2R)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol chemical structure, C15H15NO, CAS 1357301-26-8
4'-((1S,2R)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol
CAS 1357301-26-8C15H15NO
trans-2-([1,1'-Biphenyl]-4-yl)cyclopropan-1-amine hydrochloride chemical structure, C15H16ClN, CAS 1314324-11-2
trans-2-([1,1'-Biphenyl]-4-yl)cyclopropan-1-amine hydrochloride
CAS 1314324-11-2C15H16ClN
rac-(1R,2S)-2-(4-Phenylphenyl)cyclopropan-1-amine chemical structure, C15H15N, CAS 1998696-56-2
rac-(1R,2S)-2-(4-Phenylphenyl)cyclopropan-1-amine
CAS 1998696-56-2C15H15N
1-(2-{[1,1'-Biphenyl]-4-yl}cyclopropyl)methanamine chemical structure, C16H17N, CAS 1274139-91-1
1-(2-{[1,1'-Biphenyl]-4-yl}cyclopropyl)methanamine
CAS 1274139-91-1C16H17N
1-(Biphenyl-4-yl)cyclopropanecarboxylic acid isopropyl ester chemical structure, C19H20O2, CAS 1380650-64-5
1-(Biphenyl-4-yl)cyclopropanecarboxylic acid isopropyl ester
CAS 1380650-64-5C19H20O2
Ethyl 1-(4'-acetyl-[1,1'-biphenyl]-4-yl)cyclopropanecarboxylate chemical structure, C20H20O3, CAS 1380650-56-5
Ethyl 1-(4'-acetyl-[1,1'-biphenyl]-4-yl)cyclopropanecarboxylate
CAS 1380650-56-5C20H20O3
1-(4'-Acetylbiphenyl-4-yl)cyclopropanecarboxylic acid isopropyl ester chemical structure, C21H22O3, CAS 1380650-65-6
1-(4'-Acetylbiphenyl-4-yl)cyclopropanecarboxylic acid isopropyl ester
CAS 1380650-65-6C21H22O3
4'-(1-(Isopropoxycarbonyl)cyclopropyl)biphenyl-4-carboxylic acid chemical structure, C20H20O4, CAS 1380650-66-7
4'-(1-(Isopropoxycarbonyl)cyclopropyl)biphenyl-4-carboxylic acid
CAS 1380650-66-7C20H20O4