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Murcko scaffold

Ring system with 4 rings and 25 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
9
With full pages
4
Scaffold SMILES

C(=Cc1nc(-c2ccccc2)n(-c2ccccc2)n1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1nc(-c2ccccc2)n(-c2ccccc2)n1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

4-{(E)-2-[5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl]ethenyl}benzene-1,3-diol chemical structure, C22H17N3O3, CAS 519167-87-4
4-{(E)-2-[5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl]ethenyl}benzene-1,3-diol
CAS 519167-87-4C22H17N3O3
2-{3-[(E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1-phenyl-1H-1,2,4-triazol-5-yl}phenol chemical structure, C24H21N3O3, CAS 919793-98-9
2-{3-[(E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1-phenyl-1H-1,2,4-triazol-5-yl}phenol
CAS 919793-98-9C24H21N3O3
(E)-2-(3-(4-Fluorostyryl)-1-phenyl-1H-1,2,4-triazol-5-yl)phenol chemical structure, C22H16FN3O, CAS 847178-76-1
(E)-2-(3-(4-Fluorostyryl)-1-phenyl-1H-1,2,4-triazol-5-yl)phenol
CAS 847178-76-1C22H16FN3O
(E)-N-(4-(2-(5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl)vinyl)phenyl)acetamide chemical structure, C24H20N4O2, CAS 830349-03-6
(E)-N-(4-(2-(5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl)vinyl)phenyl)acetamide
CAS 830349-03-6C24H20N4O2
2-{3-[(E)-2-(4-Methoxyphenyl)ethenyl]-1-phenyl-1H-1,2,4-triazol-5-yl}phenol chemical structure, C23H19N3O2, CAS 120029-46-1
2-{3-[(E)-2-(4-Methoxyphenyl)ethenyl]-1-phenyl-1H-1,2,4-triazol-5-yl}phenol
CAS 120029-46-1C23H19N3O2
4-{(E)-2-[5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl]ethenyl}phenyl acetate chemical structure, C24H19N3O3, CAS 824419-35-4
4-{(E)-2-[5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl]ethenyl}phenyl acetate
CAS 824419-35-4C24H19N3O3
2-{3-[(E)-2-(4-Chlorophenyl)ethenyl]-1-phenyl-1H-1,2,4-triazol-5-yl}phenol chemical structure, C22H16ClN3O, CAS 701244-60-2
2-{3-[(E)-2-(4-Chlorophenyl)ethenyl]-1-phenyl-1H-1,2,4-triazol-5-yl}phenol
CAS 701244-60-2C22H16ClN3O
(E)-2-(3-(4-Hydroxystyryl)-1-phenyl-1H-1,2,4-triazol-5-yl)phenol chemical structure, C22H17N3O2, CAS 371932-15-9
(E)-2-(3-(4-Hydroxystyryl)-1-phenyl-1H-1,2,4-triazol-5-yl)phenol
CAS 371932-15-9C22H17N3O2
(E)-4-(2-(5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl)vinyl)-2-methoxyphenyl acetate chemical structure, C25H21N3O4, CAS 831212-36-3
(E)-4-(2-(5-(2-Hydroxyphenyl)-1-phenyl-1H-1,2,4-triazol-3-yl)vinyl)-2-methoxyphenyl acetate
CAS 831212-36-3C25H21N3O4