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Murcko scaffold

N-(4,5-Diphenyl-thiazol-2-yl)-benzamide scaffold

62 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
62
With full pages
3
Scaffold SMILES

O=C(Nc1nc(-c2ccccc2)c(-c2ccccc2)s1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(4,5-Diphenyl-thiazol-2-yl)-benzamide page
Murcko scaffold O=C(Nc1nc(-c2ccccc2)c(-c2ccccc2)s1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

N-[4-(4-Methoxyphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-nitrobenzamide chemical structure, C23H17N3O4S, CAS 352557-92-7
N-[4-(4-Methoxyphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-nitrobenzamide
CAS 352557-92-7C23H17N3O4S
N-[5-(3,4-Dimethylphenyl)-4-phenyl-1,3-thiazol-2-yl]-3,4,5-trimethoxybenzamide chemical structure, C27H26N2O4S, CAS 425681-78-3
N-[5-(3,4-Dimethylphenyl)-4-phenyl-1,3-thiazol-2-yl]-3,4,5-trimethoxybenzamide
CAS 425681-78-3C27H26N2O4S
N-(4,5-Diphenyl-1,3-thiazol-2-yl)-4-nitrobenzamide chemical structure, C22H15N3O3S, CAS 313550-18-4
N-(4,5-Diphenyl-1,3-thiazol-2-yl)-4-nitrobenzamide
CAS 313550-18-4C22H15N3O3S
N-(4,5-Diphenyl-thiazol-2-yl)-benzamide chemical structure, C22H16N2OS, CAS 52920-40-8
N-(4,5-Diphenyl-thiazol-2-yl)-benzamide
CAS 52920-40-8C22H16N2OS
(Z)-N-(4,5-Diphenylthiazol-2(3H)-ylidene)-4-fluorobenzamide chemical structure, C22H15FN2OS, CAS 313403-63-3
(Z)-N-(4,5-Diphenylthiazol-2(3H)-ylidene)-4-fluorobenzamide
CAS 313403-63-3C22H15FN2OS
N-(4-{4-Nitrophenyl}-5-phenyl-1,3-thiazol-2-yl)-3,4,5-trimethoxybenzamide chemical structure, C25H21N3O6S, CAS 335209-47-7
N-(4-{4-Nitrophenyl}-5-phenyl-1,3-thiazol-2-yl)-3,4,5-trimethoxybenzamide
CAS 335209-47-7C25H21N3O6S
4-Methoxy-N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide chemical structure, C24H20N2O2S, CAS 317853-89-7
4-Methoxy-N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide
CAS 317853-89-7C24H20N2O2S
3,5-Dimethoxy-N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide chemical structure, C25H22N2O3S, CAS 313553-86-5
3,5-Dimethoxy-N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide
CAS 313553-86-5C25H22N2O3S
4-(Dimethylsulfamoyl)-N-(4,5-diphenyl-1,3-thiazol-2-yl)benzamide chemical structure, C24H21N3O3S2, CAS 313529-33-8
4-(Dimethylsulfamoyl)-N-(4,5-diphenyl-1,3-thiazol-2-yl)benzamide
CAS 313529-33-8C24H21N3O3S2
N-[4-(4-Methylphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-nitrobenzamide chemical structure, C23H17N3O3S, CAS 380342-17-6
N-[4-(4-Methylphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-nitrobenzamide
CAS 380342-17-6C23H17N3O3S
4-Methoxy-N-[4-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C24H19N3O5S, CAS 311322-08-4
4-Methoxy-N-[4-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide
CAS 311322-08-4C24H19N3O5S
2-Fluoro-N-[4-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C23H16FN3O4S, CAS 352563-26-9
2-Fluoro-N-[4-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide
CAS 352563-26-9C23H16FN3O4S
N-[4-(4-Methoxyphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-methylbenzamide chemical structure, C24H20N2O2S, CAS 690990-93-3
N-[4-(4-Methoxyphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-methylbenzamide
CAS 690990-93-3C24H20N2O2S
2-Methoxy-N-[5-(4-nitrophenyl)-4-phenyl-1,3-thiazol-2-yl]benzamide chemical structure, C23H17N3O4S, CAS 5667-56-1
2-Methoxy-N-[5-(4-nitrophenyl)-4-phenyl-1,3-thiazol-2-yl]benzamide
CAS 5667-56-1C23H17N3O4S
N-[4-(4-Chlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-nitrobenzamide chemical structure, C22H14ClN3O3S, CAS 419546-59-1
N-[4-(4-Chlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-nitrobenzamide
CAS 419546-59-1C22H14ClN3O3S
N-[4,5-Bis(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-fluorobenzamide chemical structure, C24H19FN2O3S, CAS 340981-56-8
N-[4,5-Bis(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-fluorobenzamide
CAS 340981-56-8C24H19FN2O3S
2-Fluoro-N-[4-(4-methoxyphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide chemical structure, C23H17FN2O2S, CAS 419547-05-0
2-Fluoro-N-[4-(4-methoxyphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide
CAS 419547-05-0C23H17FN2O2S
2,4-Dichloro-N-[4-(2,4-dimethylphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C24H17Cl2N3O3S, CAS 419547-31-2
2,4-Dichloro-N-[4-(2,4-dimethylphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide
CAS 419547-31-2C24H17Cl2N3O3S
N-[4-(4-Methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C23H17N3O4S, CAS 419547-34-5
N-[4-(4-Methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide
CAS 419547-34-5C23H17N3O4S
2-Chloro-N-[4-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C23H16ClN3O4S, CAS 419547-51-6
2-Chloro-N-[4-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]benzamide
CAS 419547-51-6C23H16ClN3O4S
4-Chloro-N-(4,5-diphenyl-1,3-thiazol-2-yl)benzamide chemical structure, C22H15ClN2OS, CAS 325979-07-5
4-Chloro-N-(4,5-diphenyl-1,3-thiazol-2-yl)benzamide
CAS 325979-07-5C22H15ClN2OS
N-(4,5-Diphenyl-1,3-thiazol-2-yl)-3,5-dinitrobenzamide chemical structure, C22H14N4O5S, CAS 295361-86-3
N-(4,5-Diphenyl-1,3-thiazol-2-yl)-3,5-dinitrobenzamide
CAS 295361-86-3C22H14N4O5S
(Z)-N-(4,5-Diphenylthiazol-2(3H)-ylidene)-3,5-dimethoxybenzamide chemical structure, C24H20N2O3S, CAS 325978-11-8
(Z)-N-(4,5-Diphenylthiazol-2(3H)-ylidene)-3,5-dimethoxybenzamide
CAS 325978-11-8C24H20N2O3S
4-Chloro-N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide chemical structure, C23H17ClN2OS, CAS 317853-87-5
4-Chloro-N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]benzamide
CAS 317853-87-5C23H17ClN2OS