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Murcko scaffold

Ring system with 3 rings and 19 atoms

37 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 19
Chemicals: 37
With full pages: 4

Scaffold SMILES

O=C1C(=CC=Cc2ccccc2)Oc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1C(=CC=Cc2ccccc2)Oc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

(2Z)-6-Hydroxy-2-[(2E)-3-phenylprop-2-en-1-ylidene]-1-benzofuran-3(2H)-one chemical structure, C17H12O3, CAS 88281-20-3

(2Z)-6-Hydroxy-2-[(2E)-3-phenylprop-2-en-1-ylidene]-1-benzofuran-3(2H)-one

CAS 88281-20-3C₁₇H₁₂O₃

(Z)-6-Hydroxy-2-((E)-3-(2-methoxyphenyl)allylidene)benzofuran-3(2H)-one chemical structure, C18H14O4, CAS 1350919-05-9

(Z)-6-Hydroxy-2-((E)-3-(2-methoxyphenyl)allylidene)benzofuran-3(2H)-one

CAS 1350919-05-9C₁₈H₁₄O₄

2-((2E)-3-Phenylprop-2-enylidene)-6-(3-methylbut-2-enyloxy)benzo[b]furan-3-one chemical structure, C22H20O3, CAS 622808-30-4

2-((2E)-3-Phenylprop-2-enylidene)-6-(3-methylbut-2-enyloxy)benzo[b]furan-3-one

CAS 622808-30-4C₂₂H₂₀O₃

Isopropyl 2-(((Z)-2-((E)-3-(2-methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetate chemical structure, C23H22O6, CAS 622806-64-8

Isopropyl 2-(((Z)-2-((E)-3-(2-methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetate

CAS 622806-64-8C₂₃H₂₂O₆

Ethyl 2-(((Z)-3-oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetate chemical structure, C21H18O5, CAS 620547-87-7

Ethyl 2-(((Z)-3-oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetate

CAS 620547-87-7C₂₁H₁₈O₅

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl acetate chemical structure, C20H16O5, CAS 622358-52-5

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl acetate

CAS 622358-52-5C₂₀H₁₆O₅

Methyl 2-(((Z)-3-oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetate chemical structure, C20H16O5, CAS 620547-63-9

Methyl 2-(((Z)-3-oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetate

CAS 620547-63-9C₂₀H₁₆O₅

(Z)-6-Methoxy-2-((E)-3-(2-methoxyphenyl)allylidene)benzofuran-3(2H)-one chemical structure, C19H16O4, CAS 620546-92-1

(Z)-6-Methoxy-2-((E)-3-(2-methoxyphenyl)allylidene)benzofuran-3(2H)-one

CAS 620546-92-1C₁₉H₁₆O₄

2-[(Z,2E)-3-(2-Methoxyphenyl)-2-propenylidene]-6-[(2-methylallyl)oxy]-1-benzofuran-3-one chemical structure, C22H20O4, CAS 620547-40-2

2-[(Z,2E)-3-(2-Methoxyphenyl)-2-propenylidene]-6-[(2-methylallyl)oxy]-1-benzofuran-3-one

CAS 620547-40-2C₂₂H₂₀O₄

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-6-(2-oxopropoxy)benzofuran-3(2H)-one chemical structure, C21H18O5, CAS 859132-69-7

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-6-(2-oxopropoxy)benzofuran-3(2H)-one

CAS 859132-69-7C₂₁H₁₈O₅

(Z)-6-(2-Oxopropoxy)-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one chemical structure, C20H16O4, CAS 859665-46-6

(Z)-6-(2-Oxopropoxy)-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one

CAS 859665-46-6C₂₀H₁₆O₄

(Z)-6-Methoxy-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one chemical structure, C18H14O3, CAS 1695510-96-3

(Z)-6-Methoxy-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one

CAS 1695510-96-3C₁₈H₁₄O₃

Isopropyl 2-(((Z)-3-oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetate chemical structure, C22H20O5, CAS 622806-56-8

Isopropyl 2-(((Z)-3-oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetate

CAS 622806-56-8C₂₂H₂₀O₅

(Z)-3-Oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl dimethylcarbamate chemical structure, C20H17NO4, CAS 622794-13-2

(Z)-3-Oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl dimethylcarbamate

CAS 622794-13-2C₂₀H₁₇NO₄

(Z)-3-Oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl acetate chemical structure, C19H14O4, CAS 622358-48-9

(Z)-3-Oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl acetate

CAS 622358-48-9C₁₉H₁₄O₄

Methyl 2-(((Z)-2-((E)-3-(2-methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetate chemical structure, C21H18O6, CAS 620547-64-0

Methyl 2-(((Z)-2-((E)-3-(2-methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetate

CAS 620547-64-0C₂₁H₁₈O₆

Ethyl 2-(((Z)-2-((E)-3-(2-methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetate chemical structure, C22H20O6, CAS 620547-88-8

Ethyl 2-(((Z)-2-((E)-3-(2-methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetate

CAS 620547-88-8C₂₂H₂₀O₆

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl dimethylcarbamate chemical structure, C21H19NO5, CAS 622794-16-5

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl dimethylcarbamate

CAS 622794-16-5C₂₁H₁₉NO₅

(Z)-7-((Diethylamino)methyl)-6-hydroxy-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one chemical structure, C22H23NO3, CAS 896853-69-3

(Z)-7-((Diethylamino)methyl)-6-hydroxy-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one

CAS 896853-69-3C₂₂H₂₃NO₃

(Z)-7-((Diethylamino)methyl)-6-hydroxy-2-((E)-3-(2-methoxyphenyl)allylidene)benzofuran-3(2H)-one chemical structure, C23H25NO4, CAS 899390-71-7

(Z)-7-((Diethylamino)methyl)-6-hydroxy-2-((E)-3-(2-methoxyphenyl)allylidene)benzofuran-3(2H)-one

CAS 899390-71-7C₂₃H₂₅NO₄

(Z)-7-((Dimethylamino)methyl)-6-hydroxy-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one chemical structure, C20H19NO3, CAS 899411-94-0

(Z)-7-((Dimethylamino)methyl)-6-hydroxy-2-((E)-3-phenylallylidene)benzofuran-3(2H)-one

CAS 899411-94-0C₂₀H₁₉NO₃

(2Z)-7-{[Bis(2-methoxyethyl)amino]methyl}-6-hydroxy-2-[(2E)-3-(2-methoxyphenyl)prop-2-en-1-ylidene]-1-benzofuran-3(2H)-one chemical structure, C25H29NO6, CAS 899391-86-7

(2Z)-7-{[Bis(2-methoxyethyl)amino]methyl}-6-hydroxy-2-[(2E)-3-(2-methoxyphenyl)prop-2-en-1-ylidene]-1-benzofuran-3(2H)-one

CAS 899391-86-7C₂₅H₂₉NO₆

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl diethylcarbamate chemical structure, C23H23NO5, CAS 622797-42-6

(Z)-2-((E)-3-(2-Methoxyphenyl)allylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl diethylcarbamate

CAS 622797-42-6C₂₃H₂₃NO₅

(Z)-3-Oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl diethylcarbamate chemical structure, C22H21NO4, CAS 622797-37-9

(Z)-3-Oxo-2-((E)-3-phenylallylidene)-2,3-dihydrobenzofuran-6-yl diethylcarbamate

CAS 622797-37-9C₂₂H₂₁NO₄