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Murcko scaffold

Ring system with 3 rings and 26 atoms

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
22
With full pages
3
Scaffold SMILES

O=C(CN1CCN(CCCOc2ccccc2)CC1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1CCN(CCCOc2ccccc2)CC1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

Ranolazine chemical structure, C24H33N3O4, CAS 95635-55-5
Ranolazine
CAS 95635-55-5C24H33N3O4
Ranolazine hydrochloride chemical structure, C24H35Cl2N3O4, CAS 95635-56-6
Ranolazine hydrochloride
CAS 95635-56-6C24H35Cl2N3O4
(R)-Ranolazine chemical structure, C24H33N3O4, CAS 114246-80-9
(R)-Ranolazine
CAS 114246-80-9C24H33N3O4
(S)-Ranolazine chemical structure, C24H33N3O4, CAS 114246-81-0
(S)-Ranolazine
CAS 114246-81-0C24H33N3O4
Desmethoxy ranolazine chemical structure, C23H31N3O3, CAS 755711-09-2
Desmethoxy ranolazine
CAS 755711-09-2C23H31N3O3
N-(2,4-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide chemical structure, C24H33N3O4, CAS 701193-65-9
N-(2,4-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide
CAS 701193-65-9C24H33N3O4
m-Ranolazine chemical structure, C24H33N3O4, CAS 1393717-46-8
m-Ranolazine
CAS 1393717-46-8C24H33N3O4
1-Piperazineacetamide, 4-(3-(2-chlorophenoxy)-2-hydroxypropyl)-N-(2,6-dimethylphenyl)- chemical structure, C23H30ClN3O3, CAS 1647922-32-4
1-Piperazineacetamide, 4-(3-(2-chlorophenoxy)-2-hydroxypropyl)-N-(2,6-dimethylphenyl)-
CAS 1647922-32-4C23H30ClN3O3
p-Ranolazine chemical structure, C24H33N3O4, CAS 1393717-45-7
p-Ranolazine
CAS 1393717-45-7C24H33N3O4
Ranolazine-d5 chemical structure, C24H33N3O4, CAS 1092804-87-9
Ranolazine-d5
CAS 1092804-87-9C24H33N3O4
Ranolazine-d3 chemical structure, C24H33N3O4, CAS 1054624-77-9
Ranolazine-d3
CAS 1054624-77-9C24H33N3O4
Ranolazine-D8 chemical structure, C24H33N3O4, CAS 1092804-88-0
Ranolazine-D8
CAS 1092804-88-0C24H33N3O4
O-Desmethyl ranolazine chemical structure, C23H31N3O4, CAS 172430-45-4
O-Desmethyl ranolazine
CAS 172430-45-4C23H31N3O4
Ranolazine-D8 dihydrochloride chemical structure, C24H35Cl2N3O4, CAS 1219802-60-4
Ranolazine-D8 dihydrochloride
CAS 1219802-60-4C24H35Cl2N3O4
Deuterated ranolazine chemical structure, C24H33N3O4, CAS 1092806-25-1
Deuterated ranolazine
CAS 1092806-25-1C24H33N3O4
Desmethoxy ranolazine-d5 chemical structure, C23H31N3O3, CAS 1794788-57-0
Desmethoxy ranolazine-d5
CAS 1794788-57-0C23H31N3O3
Desmethyl ranolazine-d5 chemical structure, C23H31N3O4, CAS 1329834-18-5
Desmethyl ranolazine-d5
CAS 1329834-18-5C23H31N3O4
Ranolazine bis(N-oxide) chemical structure, C24H33N3O6, CAS 1246816-00-1
Ranolazine bis(N-oxide)
CAS 1246816-00-1C24H33N3O6
1-Piperazineacetamide, 4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-N-(2-(hydroxymethyl)-6-methylphenyl)- chemical structure, C24H33N3O5, CAS 172430-44-3
1-Piperazineacetamide, 4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-N-(2-(hydroxymethyl)-6-methylphenyl)-
CAS 172430-44-3C24H33N3O5
Ranolazine metabolite CVT-5029 chemical structure, C24H33N3O5, CAS 172430-47-6
Ranolazine metabolite CVT-5029
CAS 172430-47-6C24H33N3O5
1-(2-((2,6-Dimethylphenyl)amino)-2-oxoethyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazine 1-oxide chemical structure, C24H33N3O5, CAS 2731041-97-5
1-(2-((2,6-Dimethylphenyl)amino)-2-oxoethyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazine 1-oxide
CAS 2731041-97-5C24H33N3O5
Ranolazine 4-N-oxide chemical structure, C24H33N3O5, CAS 2725395-82-2
Ranolazine 4-N-oxide
CAS 2725395-82-2C24H33N3O5