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Murcko scaffold

Ring system with 3 rings and 24 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
9
With full pages
4
Scaffold SMILES

O=S(=O)(NCCc1ccccc1)c1ccc(-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCCc1ccccc1)c1ccc(-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

72 kDa type IV collagenase chemical structure, C21H19NO4S, CAS 146480-35-5
72 kDa type IV collagenase
CAS 146480-35-5C21H19NO4S
4'-Methyl-N-phenethyl-[1,1'-biphenyl]-4-sulfonamide chemical structure, C21H21NO2S, CAS 670271-71-3
4'-Methyl-N-phenethyl-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-71-3C21H21NO2S
3-({[4-(4-Nitrophenyl)phenyl]sulfonyl}(2-phenylethyl)amino)propanenitrile chemical structure, C23H21N3O4S, CAS 313496-44-5
3-({[4-(4-Nitrophenyl)phenyl]sulfonyl}(2-phenylethyl)amino)propanenitrile
CAS 313496-44-5C23H21N3O4S
4'-Methoxy-N-phenethyl-[1,1'-biphenyl]-4-sulfonamide chemical structure, C21H21NO3S, CAS 670271-72-4
4'-Methoxy-N-phenethyl-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-72-4C21H21NO3S
(2R)-((4-Biphenylylsulfonyl)amino)-N-hydroxy-3-phenylpropionamide chemical structure, C21H20N2O4S, CAS 193807-60-2
(2R)-((4-Biphenylylsulfonyl)amino)-N-hydroxy-3-phenylpropionamide
CAS 193807-60-2C21H20N2O4S
Mmp-2/mmp-9 inhibitor i chemical structure, C21H19NO4S, CAS 193807-58-8
Mmp-2/mmp-9 inhibitor i
CAS 193807-58-8C21H19NO4S
4'-Methoxy-N-methyl-N-(2-phenylethyl)[1,1'-biphenyl]-4-sulfonamide chemical structure, C22H23NO3S, CAS 690662-98-7
4'-Methoxy-N-methyl-N-(2-phenylethyl)[1,1'-biphenyl]-4-sulfonamide
CAS 690662-98-7C22H23NO3S
((4'-Chloro-[1,1'-biphenyl]-4-yl)sulfonyl)phenylalanine chemical structure, C21H18ClNO4S, CAS 1449133-06-5
((4'-Chloro-[1,1'-biphenyl]-4-yl)sulfonyl)phenylalanine
CAS 1449133-06-5C21H18ClNO4S
N-([1,1'-Biphenyl]-4-sulfonyl)-L-phenylalanine chemical structure, C21H19NO4S, CAS 229165-58-6
N-([1,1'-Biphenyl]-4-sulfonyl)-L-phenylalanine
CAS 229165-58-6C21H19NO4S