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Murcko scaffold

Ring system with 2 rings and 12 atoms

1,305 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
1,305
With full pages
33
Scaffold SMILES

c1cc(N2CCCCC2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(N2CCCCC2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,305 chemicals

Acetic acid, ((6-(1-piperidinyl)-4-pyrimidinyl)thio)-, methyl ester chemical structure, C12H17N3O2S, CAS 95546-88-6
Acetic acid, ((6-(1-piperidinyl)-4-pyrimidinyl)thio)-, methyl ester
CAS 95546-88-6C12H17N3O2S
Acetic acid, ((6-(1-piperidinyl)-4-pyrimidinyl)thio)-, hydrazide chemical structure, C11H17N5OS, CAS 95546-91-1
Acetic acid, ((6-(1-piperidinyl)-4-pyrimidinyl)thio)-, hydrazide
CAS 95546-91-1C11H17N5OS
Acetic acid, ((6-(1-piperidinyl)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide chemical structure, C14H21N5OS, CAS 95546-94-4
Acetic acid, ((6-(1-piperidinyl)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide
CAS 95546-94-4C14H21N5OS
2-Chloro-4-(piperidin-1-yl)pyrimidine chemical structure, C9H12ClN3, CAS 5429-00-5
2-Chloro-4-(piperidin-1-yl)pyrimidine
CAS 5429-00-5C9H12ClN3
4-Piperidin-1-ylpyrimidin-2-amine chemical structure, C9H14N4, CAS 69193-22-2
4-Piperidin-1-ylpyrimidin-2-amine
CAS 69193-22-2C9H14N4
2-(Methylsulfanyl)-4-(piperidin-1-yl)pyrimidine chemical structure, C10H15N3S, CAS 500874-45-3
2-(Methylsulfanyl)-4-(piperidin-1-yl)pyrimidine
CAS 500874-45-3C10H15N3S
4-Chloro-6-piperidin-1-ylpyrimidine chemical structure, C9H12ClN3, CAS 1722-14-1
4-Chloro-6-piperidin-1-ylpyrimidine
CAS 1722-14-1C9H12ClN3
2,4-Diamino-6-piperidinopyrimidine chemical structure, C9H15N5, CAS 24867-26-3
2,4-Diamino-6-piperidinopyrimidine
CAS 24867-26-3C9H15N5
4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine chemical structure, C9H13FN4, CAS 188987-81-7
4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine
CAS 188987-81-7C9H13FN4
2-Amino-4-piperidino-6-methylpyrimidine chemical structure, C10H16N4, CAS 91717-22-5
2-Amino-4-piperidino-6-methylpyrimidine
CAS 91717-22-5C10H16N4
4-Chloro-2-(methylsulfanyl)-6-(1-piperidinyl)-5-pyrimidinecarbaldehyde chemical structure, C11H14ClN3OS, CAS 445040-60-8
4-Chloro-2-(methylsulfanyl)-6-(1-piperidinyl)-5-pyrimidinecarbaldehyde
CAS 445040-60-8C11H14ClN3OS
4-Chloro-6-piperidin-1-yl-pyrimidin-5-ylamine chemical structure, C9H13ClN4, CAS 84762-70-9
4-Chloro-6-piperidin-1-yl-pyrimidin-5-ylamine
CAS 84762-70-9C9H13ClN4
2-Amino-4-chloro-6-(piperidin-1-yl)pyrimidine-5-carbaldehyde chemical structure, C10H13ClN4O, CAS 865660-47-5
2-Amino-4-chloro-6-(piperidin-1-yl)pyrimidine-5-carbaldehyde
CAS 865660-47-5C10H13ClN4O
Methyl 1-(2-amino-6-chloropyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C11H15ClN4O2, CAS 866050-01-3
Methyl 1-(2-amino-6-chloropyrimidin-4-yl)piperidine-4-carboxylate
CAS 866050-01-3C11H15ClN4O2
4-Chloro-6-piperidin-1-yl-pyrimidin-2-ylamine chemical structure, C9H13ClN4, CAS 104637-64-1
4-Chloro-6-piperidin-1-yl-pyrimidin-2-ylamine
CAS 104637-64-1C9H13ClN4
1-(2-Amino-6-chloro-4-pyrimidinyl)-4-piperidinecarboxamide chemical structure, C10H14ClN5O, CAS 339017-63-9
1-(2-Amino-6-chloro-4-pyrimidinyl)-4-piperidinecarboxamide
CAS 339017-63-9C10H14ClN5O
1-[6-Chloro-2-(methylsulfanyl)-4-pyrimidinyl]-4-piperidinecarboxamide chemical structure, C11H15ClN4OS, CAS 339017-90-2
1-[6-Chloro-2-(methylsulfanyl)-4-pyrimidinyl]-4-piperidinecarboxamide
CAS 339017-90-2C11H15ClN4OS
2-(Methylsulfanyl)-4-piperidino-6-(trifluoromethyl)pyrimidine chemical structure, C11H14F3N3S, CAS 339019-58-8
2-(Methylsulfanyl)-4-piperidino-6-(trifluoromethyl)pyrimidine
CAS 339019-58-8C11H14F3N3S
5-Bromo-2-chloro-4-(piperidin-1-yl)pyrimidine chemical structure, C9H11BrClN3, CAS 62880-67-5
5-Bromo-2-chloro-4-(piperidin-1-yl)pyrimidine
CAS 62880-67-5C9H11BrClN3
2-Chloro-5-fluoro-4-piperidin-1-ylpyrimidine chemical structure, C9H11ClFN3, CAS 40423-82-3
2-Chloro-5-fluoro-4-piperidin-1-ylpyrimidine
CAS 40423-82-3C9H11ClFN3
Ethyl 2-(methylsulfanyl)-4-(piperidin-1-yl)pyrimidine-5-carboxylate chemical structure, C13H19N3O2S, CAS 100451-24-9
Ethyl 2-(methylsulfanyl)-4-(piperidin-1-yl)pyrimidine-5-carboxylate
CAS 100451-24-9C13H19N3O2S
1-(6-Amino-5-nitropyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C10H14N6O3, CAS 450345-79-6
1-(6-Amino-5-nitropyrimidin-4-yl)piperidine-4-carboxamide
CAS 450345-79-6C10H14N6O3
6-(4-Methylpiperidin-1-yl)-5-nitropyrimidin-4-amine chemical structure, C10H15N5O2, CAS 450345-73-0
6-(4-Methylpiperidin-1-yl)-5-nitropyrimidin-4-amine
CAS 450345-73-0C10H15N5O2
Ethyl 1-(6-amino-5-nitropyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C12H17N5O4, CAS 450345-77-4
Ethyl 1-(6-amino-5-nitropyrimidin-4-yl)piperidine-4-carboxylate
CAS 450345-77-4C12H17N5O4