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Murcko scaffold

Ring system with 3 rings and 13 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
11
With full pages
3
Scaffold SMILES

c1ccc2c(c1)CCn1cnnc1-2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CCn1cnnc1-2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

1,2,4-Triazolo(3,4-a)isoquinoline, 5,6-dihydro-3-(trifluoromethyl)- chemical structure, C11H8F3N3, CAS 35515-45-8
1,2,4-Triazolo(3,4-a)isoquinoline, 5,6-dihydro-3-(trifluoromethyl)-
CAS 35515-45-8C11H8F3N3
1,2,4-Triazolo(3,4-a)isoquinoline, 5,6-dihydro-8,9-dimethoxy- chemical structure, C12H13N3O2, CAS 35515-48-1
1,2,4-Triazolo(3,4-a)isoquinoline, 5,6-dihydro-8,9-dimethoxy-
CAS 35515-48-1C12H13N3O2
3,5,5-Trimethyl-5,6-dihydro-[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C13H15N3, CAS 163557-56-0
3,5,5-Trimethyl-5,6-dihydro-[1,2,4]triazolo[3,4-a]isoquinoline
CAS 163557-56-0C13H15N3
5,5-Dimethyl-3-propyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C15H19N3, CAS 332413-37-3
5,5-Dimethyl-3-propyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline
CAS 332413-37-3C15H19N3
5,5,8,9-Tetramethyl-3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C15H16F3N3, CAS 332413-30-6
5,5,8,9-Tetramethyl-3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline
CAS 332413-30-6C15H16F3N3
5,5-Dimethyl-3-(trifluoromethyl)-6H-[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C13H12F3N3, CAS 304435-51-6
5,5-Dimethyl-3-(trifluoromethyl)-6H-[1,2,4]triazolo[3,4-a]isoquinoline
CAS 304435-51-6C13H12F3N3
8,9-Dimethoxy-3,5,5-trimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C15H19N3O2, CAS 314030-63-2
8,9-Dimethoxy-3,5,5-trimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline
CAS 314030-63-2C15H19N3O2
8,9-Dimethoxy-5,5-dimethyl-3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C15H16F3N3O2, CAS 296793-67-4
8,9-Dimethoxy-5,5-dimethyl-3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline
CAS 296793-67-4C15H16F3N3O2
5,6-Dihydro-[1,2,4]triazolo[3,4-a]isoquinolin-9-amine chemical structure, C10H10N4, CAS 58021-55-9
5,6-Dihydro-[1,2,4]triazolo[3,4-a]isoquinolin-9-amine
CAS 58021-55-9C10H10N4
3-Methyl-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C11H11N3, CAS 27107-22-8
3-Methyl-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline
CAS 27107-22-8C11H11N3
(5R,6S)-3,5,6-Tribromo-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline chemical structure, C10H6Br3N3, CAS 35515-35-6
(5R,6S)-3,5,6-Tribromo-5,6-dihydro[1,2,4]triazolo[3,4-a]isoquinoline
CAS 35515-35-6C10H6Br3N3