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Murcko scaffold

Ring system with 3 rings and 18 atoms

37 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
37
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)N1CCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)N1CCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

1-(2,3-Dihydroindol-1-yl)-2-(4-methoxyphenyl)ethanone chemical structure, C17H17NO2, CAS 346692-24-8
1-(2,3-Dihydroindol-1-yl)-2-(4-methoxyphenyl)ethanone
CAS 346692-24-8C17H17NO2
1-(2,3-Dihydroindol-1-yl)-2-(2-nitrophenyl)ethanone chemical structure, C16H14N2O3, CAS 349409-82-1
1-(2,3-Dihydroindol-1-yl)-2-(2-nitrophenyl)ethanone
CAS 349409-82-1C16H14N2O3
2-(2-Chloro-6-fluorophenyl)-1-(2,3-dihydroindol-1-yl)ethanone chemical structure, C16H13ClFNO, CAS 710988-32-2
2-(2-Chloro-6-fluorophenyl)-1-(2,3-dihydroindol-1-yl)ethanone
CAS 710988-32-2C16H13ClFNO
1-(2,3-Dihydroindol-1-yl)-2-(4-methylphenyl)ethanone chemical structure, C17H17NO, CAS 599162-34-2
1-(2,3-Dihydroindol-1-yl)-2-(4-methylphenyl)ethanone
CAS 599162-34-2C17H17NO
1-[(4-Chlorophenyl)acetyl]indoline chemical structure, C16H14ClNO, CAS 349428-01-9
1-[(4-Chlorophenyl)acetyl]indoline
CAS 349428-01-9C16H14ClNO
1-(2-Phenylbutanoyl)indoline chemical structure, C18H19NO, CAS 349088-99-9
1-(2-Phenylbutanoyl)indoline
CAS 349088-99-9C18H19NO
1-(2,3-Dihydro-1H-indol-1-yl)-2-(4-nitrophenyl)propan-1-one chemical structure, C17H16N2O3, CAS 693831-10-6
1-(2,3-Dihydro-1H-indol-1-yl)-2-(4-nitrophenyl)propan-1-one
CAS 693831-10-6C17H16N2O3
1-(2,3-Dihydroindol-1-yl)-2-(3-methylphenyl)ethanone chemical structure, C17H17NO, CAS 898135-01-8
1-(2,3-Dihydroindol-1-yl)-2-(3-methylphenyl)ethanone
CAS 898135-01-8C17H17NO
1-(2-Methyl-2,3-dihydroindol-1-yl)-2-(2-methylphenyl)ethanone chemical structure, C18H19NO, CAS 898156-86-0
1-(2-Methyl-2,3-dihydroindol-1-yl)-2-(2-methylphenyl)ethanone
CAS 898156-86-0C18H19NO
1-(6-Chloro-2,3-dihydro-1H-indol-1-yl)-2-(3,4-dimethoxyphenyl)ethan-1-one chemical structure, C18H18ClNO3, CAS 61761-85-1
1-(6-Chloro-2,3-dihydro-1H-indol-1-yl)-2-(3,4-dimethoxyphenyl)ethan-1-one
CAS 61761-85-1C18H18ClNO3
2-(4-Chlorophenyl)-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)ethanone chemical structure, C17H16ClNO, CAS 893239-91-3
2-(4-Chlorophenyl)-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)ethanone
CAS 893239-91-3C17H16ClNO
2-(4-Fluorophenyl)-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)ethanone chemical structure, C17H16FNO, CAS 893239-96-8
2-(4-Fluorophenyl)-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)ethanone
CAS 893239-96-8C17H16FNO
2-(4-Aminophenyl)-1-(2,3-dihydro-1H-indol-1-yl)ethan-1-one chemical structure, C16H16N2O, CAS 953725-03-6
2-(4-Aminophenyl)-1-(2,3-dihydro-1H-indol-1-yl)ethan-1-one
CAS 953725-03-6C16H16N2O
1-(2-Phenylacetyl)indoline-2-carboxamide chemical structure, C17H16N2O2, CAS 1097723-47-1
1-(2-Phenylacetyl)indoline-2-carboxamide
CAS 1097723-47-1C17H16N2O2
1-(2-(4-Ethoxyphenyl)acetyl)indoline-2-carboxamide chemical structure, C19H20N2O3, CAS 1099656-63-9
1-(2-(4-Ethoxyphenyl)acetyl)indoline-2-carboxamide
CAS 1099656-63-9C19H20N2O3
1-(2-(4-Chlorophenyl)acetyl)indoline-2-carboxamide chemical structure, C17H15ClN2O2, CAS 1099656-86-6
1-(2-(4-Chlorophenyl)acetyl)indoline-2-carboxamide
CAS 1099656-86-6C17H15ClN2O2
1-(2-(4-Methoxyphenyl)acetyl)-N-methylindoline-2-carboxamide chemical structure, C19H20N2O3, CAS 1103514-40-4
1-(2-(4-Methoxyphenyl)acetyl)-N-methylindoline-2-carboxamide
CAS 1103514-40-4C19H20N2O3
1-(2-(3,4-Dimethoxyphenyl)acetyl)-N-methylindoline-2-carboxamide chemical structure, C20H22N2O4, CAS 1103514-41-5
1-(2-(3,4-Dimethoxyphenyl)acetyl)-N-methylindoline-2-carboxamide
CAS 1103514-41-5C20H22N2O4
1-(2-(4-Nitrophenyl)acetyl)indoline-2-carboxamide chemical structure, C17H15N3O4, CAS 1104225-67-3
1-(2-(4-Nitrophenyl)acetyl)indoline-2-carboxamide
CAS 1104225-67-3C17H15N3O4
1-(2-(4-Ethoxyphenyl)acetyl)-N-methylindoline-2-carboxamide chemical structure, C20H22N2O3, CAS 1103514-42-6
1-(2-(4-Ethoxyphenyl)acetyl)-N-methylindoline-2-carboxamide
CAS 1103514-42-6C20H22N2O3
1-[2-(4-Fluorophenyl)acetyl]-N-methyl-2,3-dihydro-1H-indole-2-carboxamide chemical structure, C18H17FN2O2, CAS 1103514-43-7
1-[2-(4-Fluorophenyl)acetyl]-N-methyl-2,3-dihydro-1H-indole-2-carboxamide
CAS 1103514-43-7C18H17FN2O2
1-(2-(3,4-Dimethoxyphenyl)acetyl)-N-ethylindoline-2-carboxamide chemical structure, C21H24N2O4, CAS 1100790-85-9
1-(2-(3,4-Dimethoxyphenyl)acetyl)-N-ethylindoline-2-carboxamide
CAS 1100790-85-9C21H24N2O4
[2-(2,3-Dihydro-1H-indol-1-yl)-2-oxo-1-phenylethyl]amine chemical structure, C16H16N2O, CAS 1093414-20-0
[2-(2,3-Dihydro-1H-indol-1-yl)-2-oxo-1-phenylethyl]amine
CAS 1093414-20-0C16H16N2O
1-(6-Amino-2,3-dihydro-1H-indol-1-yl)-2-(3-methoxyphenyl)ethan-1-one chemical structure, C17H18N2O2, CAS 1021135-13-6
1-(6-Amino-2,3-dihydro-1H-indol-1-yl)-2-(3-methoxyphenyl)ethan-1-one
CAS 1021135-13-6C17H18N2O2