Murcko scaffold
Thieno(2,3-b)pyrazine scaffold
69 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 69
- With full pages
- 7
Scaffold SMILES
c1cnc2sccc2n1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 69 chemicals
![Methyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate chemical structure, C8H7N3O2S, CAS 244014-85-5](/s/PSFBMJMQOVCYFD-UHFFFAOYSA-N.svg)
Methyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate
CAS 244014-85-5C8H7N3O2S
![Ethyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate chemical structure, C9H9N3O2S, CAS 56881-21-1](/s/JLBXHMLWNKGFAV-UHFFFAOYSA-N.svg)
Ethyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate
CAS 56881-21-1C9H9N3O2S
![Thieno[2,3-b]pyrazine-6-carboxylic acid chemical structure, C7H4N2O2S, CAS 59944-79-5](/s/MEHCDDSVVYRWJT-UHFFFAOYSA-N.svg)
Thieno[2,3-b]pyrazine-6-carboxylic acid
CAS 59944-79-5C7H4N2O2S
![Thieno[2,3-b]pyrazine-6-carbaldehyde chemical structure, C7H4N2OS, CAS 857283-69-3](/s/PDSFQJXYTQJKFG-UHFFFAOYSA-N.svg)
Thieno[2,3-b]pyrazine-6-carbaldehyde
CAS 857283-69-3C7H4N2OS
![7-Methoxythieno[2,3-b]pyrazine-6-carboxylic acid chemical structure, C8H6N2O3S, CAS 521948-54-9](/s/LBUFPANPRIBHPA-UHFFFAOYSA-N.svg)
7-Methoxythieno[2,3-b]pyrazine-6-carboxylic acid
CAS 521948-54-9C8H6N2O3S
![7-Ethoxythieno[2,3-b]pyrazine-6-carboxylic acid chemical structure, C9H8N2O3S, CAS 521948-77-6](/s/HIFLIKMYAAAUMH-UHFFFAOYSA-N.svg)
7-Ethoxythieno[2,3-b]pyrazine-6-carboxylic acid
CAS 521948-77-6C9H8N2O3S
![7-(Methylthio)thieno[2,3-b]pyrazine-6-carboxylic acid chemical structure, C8H6N2O2S2, CAS 521948-60-7](/s/ZIDVHEYYVIWTBC-UHFFFAOYSA-N.svg)
7-(Methylthio)thieno[2,3-b]pyrazine-6-carboxylic acid
CAS 521948-60-7C8H6N2O2S2
![7-[(Carboxycarbonyl)amino]thieno[2,3-b]pyrazine-6-carboxylic acid chemical structure, C9H5N3O5S, CAS 243463-04-9](/s/QGIFCOBNZZDQDV-UHFFFAOYSA-N.svg)
7-[(Carboxycarbonyl)amino]thieno[2,3-b]pyrazine-6-carboxylic acid
CAS 243463-04-9C9H5N3O5S
![Ethyl 7-amino-3-methylthieno[2,3-b]pyrazine-6-carboxylate chemical structure, C10H11N3O2S, CAS 181284-15-1](/s/PCPMQXBPBDACCA-UHFFFAOYSA-N.svg)
Ethyl 7-amino-3-methylthieno[2,3-b]pyrazine-6-carboxylate
CAS 181284-15-1C10H11N3O2S
![Thieno[2,3-b]pyrazine-6-carboxylic acid, 7-amino-2-chloro-, ethyl ester chemical structure, C9H8ClN3O2S, CAS 208994-00-7](/s/GOVBQTQQLRNYKG-UHFFFAOYSA-N.svg)
Thieno[2,3-b]pyrazine-6-carboxylic acid, 7-amino-2-chloro-, ethyl ester
CAS 208994-00-7C9H8ClN3O2S
![Thieno[2,3-b]pyrazine-6-carboxylic acid, 7-amino-, ethyl ester, 1-oxide chemical structure, C9H9N3O3S, CAS 208993-99-1](/s/SXUZSRMVGATVKG-UHFFFAOYSA-N.svg)
Thieno[2,3-b]pyrazine-6-carboxylic acid, 7-amino-, ethyl ester, 1-oxide
CAS 208993-99-1C9H9N3O3S
![7-Aminothieno[2,3-b]pyrazine-6-carboxamide chemical structure, C7H6N4OS, CAS 55557-49-8](/s/TUFRSONEDFLPFX-UHFFFAOYSA-N.svg)
7-Aminothieno[2,3-b]pyrazine-6-carboxamide
CAS 55557-49-8C7H6N4OS
![7-Aminothieno[2,3-b]pyrazine-6-carboxylic acid chemical structure, C7H5N3O2S, CAS 56881-31-3](/s/UJUCBOIXAMPUQL-UHFFFAOYSA-N.svg)
7-Aminothieno[2,3-b]pyrazine-6-carboxylic acid
CAS 56881-31-3C7H5N3O2S
![Ethyl thieno[2,3-b]pyrazine-6-carboxylate chemical structure, C9H8N2O2S, CAS 59944-77-3](/s/BPEISRFZSPQOLU-UHFFFAOYSA-N.svg)
Ethyl thieno[2,3-b]pyrazine-6-carboxylate
CAS 59944-77-3C9H8N2O2S
Thieno(2,3-b)pyrazine
CAS 56088-28-9C6H4N2S
![Ethyl 7-chlorothieno[2,3-b]pyrazine-6-carboxylate chemical structure, C9H7ClN2O2S, CAS 59944-80-8](/s/QHHINHUYJZYJER-UHFFFAOYSA-N.svg)
Ethyl 7-chlorothieno[2,3-b]pyrazine-6-carboxylate
CAS 59944-80-8C9H7ClN2O2S
![7-Chlorothieno[2,3-b]pyrazine-6-carboxylic acid chemical structure, C7H3ClN2O2S, CAS 1368311-23-2](/s/LKNPLHFPOQGQQY-UHFFFAOYSA-N.svg)
7-Chlorothieno[2,3-b]pyrazine-6-carboxylic acid
CAS 1368311-23-2C7H3ClN2O2S
![7-Chlorothieno[2,3-b]pyrazine chemical structure, C6H3ClN2S, CAS 59944-74-0](/s/KRCMBGHFNZGMDA-UHFFFAOYSA-N.svg)
7-Chlorothieno[2,3-b]pyrazine
CAS 59944-74-0C6H3ClN2S
![Thieno[2,3-b]pyrazin-7-amine chemical structure, C6H5N3S, CAS 59944-75-1](/s/ZRVKSPNBHZCQKY-UHFFFAOYSA-N.svg)
Thieno[2,3-b]pyrazin-7-amine
CAS 59944-75-1C6H5N3S
![Methyl 7-amino-2-chlorothieno[2,3-b]pyrazine-6-carboxylate chemical structure, C8H6ClN3O2S, CAS 263143-71-1](/s/RNZNJYAVQYLTIY-UHFFFAOYSA-N.svg)
Methyl 7-amino-2-chlorothieno[2,3-b]pyrazine-6-carboxylate
CAS 263143-71-1C8H6ClN3O2S
![Methyl 6-aminothieno[2,3-b]pyrazine-7-carboxylate chemical structure, C8H7N3O2S, CAS 243463-05-0](/s/UCRLRMCBCOTDRO-UHFFFAOYSA-N.svg)
Methyl 6-aminothieno[2,3-b]pyrazine-7-carboxylate
CAS 243463-05-0C8H7N3O2S
![7-Bromothieno[2,3-b]pyrazine chemical structure, C6H3BrN2S, CAS 1126824-72-3](/s/LKUNJISTXIJLSP-UHFFFAOYSA-N.svg)
7-Bromothieno[2,3-b]pyrazine
CAS 1126824-72-3C6H3BrN2S
![tert-Butyl thieno[2,3-b]pyrazin-6-ylcarbamate chemical structure, C11H13N3O2S, CAS 936361-26-1](/s/LDSBWSVXMPUNPQ-UHFFFAOYSA-N.svg)
tert-Butyl thieno[2,3-b]pyrazin-6-ylcarbamate
CAS 936361-26-1C11H13N3O2S
![Thieno[2,3-b]pyrazin-6-amine chemical structure, C6H5N3S, CAS 936361-27-2](/s/XEVJPNPLHUFWDU-UHFFFAOYSA-N.svg)
Thieno[2,3-b]pyrazin-6-amine
CAS 936361-27-2C6H5N3S
- Thieno[2,3-b]pyrazin-6-ylmethanol857283-70-6C7H6N2OS
- 7-(Methylamino)thieno[2,3-b]pyrazine-6-carboxylic acid1351238-08-8C8H7N3O2S
- Ethyl 7-bromothieno[2,3-b]pyrazine-6-carboxylate1351238-30-6C9H7BrN2O2S
- Methyl 7-(methylamino)thieno[2,3-b]pyrazine-6-carboxylate2639413-06-0C9H9N3O2S
- Ethyl 7-amino-3-chlorothieno[2,3-b]pyrazine-6-carboxylate181284-02-6C9H8ClN3O2S
- 3-Chlorothieno[2,3-b]pyrazine-6-carboxylic acid1351238-68-0C7H3ClN2O2S
- Thieno[2,3-b]pyrazine-2-carboxylic acid1369094-28-9C7H4N2O2S
- 6-Bromo-2-chlorothieno[2,3-b]pyrazine1782214-35-0C6H2BrClN2S
- 7-Bromothieno[2,3-b]pyrazine-6-carboxylic acid1779899-22-7C7H3BrN2O2S
- Ethyl 7-(methylamino)thieno[2,3-b]pyrazine-6-carboxylate181284-23-1C10H11N3O2S
- 7-(2,2,2-Trifluoro-N-methylacetamido)thieno[2,3-b]pyrazine-6-carboxylic acid2523435-38-1C10H6F3N3O3S
- Methyl 2-chlorothieno[2,3-b]pyrazine-6-carboxylate1351238-18-0C8H5ClN2O2S
- 2-Chlorothieno[2,3-b]pyrazine-6-carboxylic acid1351238-21-5C7H3ClN2O2S
- Methyl 3-chlorothieno[2,3-b]pyrazine-6-carboxylate1351238-67-9C8H5ClN2O2S
- Methyl thieno[2,3-b]pyrazine-6-carboxylate1824388-08-0C8H6N2O2S
- 2-Chlorothieno[2,3-b]pyrazine-7-carboxylic acid1812188-70-7C7H3ClN2O2S
- Methyl 2-chlorothieno[2,3-b]pyrazine-7-carboxylate1812188-69-4C8H5ClN2O2S
- Methyl thieno[2,3-b]pyrazine-7-carboxylate1812188-67-2C8H6N2O2S
- Ethyl 7-amino-2-bromothieno[2,3-b]pyrazine-6-carboxylate1629227-24-2C9H8BrN3O2S
- 7-Amino-2-bromothieno[2,3-b]pyrazine-6-carboxylic acid2007925-10-0C7H4BrN3O2S
- 2-Bromothieno[2,3-b]pyrazin-7-amine1629227-26-4C6H4BrN3S
- Methyl 7-bromothieno(2,3-b)pyrazine-6-carboxylate1824631-62-0C8H5BrN2O2S
- Methyl 7-amino-2-ethylthieno[2,3-b]pyrazine-6-carboxylate2123445-32-7C10H11N3O2S
- 7-Amino-3-methylthieno[2,3-b]pyrazine-6-carboxylic acid2123445-28-1C8H7N3O2S
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