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Murcko scaffold

5,6,7,8-Tetrahydropteridin-4(1H)-one scaffold

61 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
61
With full pages
13
Scaffold SMILES

O=c1nc[nH]c2c1NCCN2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydropteridin-4(1H)-one page
Murcko scaffold O=c1nc[nH]c2c1NCCN2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 61 of 61 chemicals

(7S)-2-Amino-7-methyl-5,6,7,8-tetrahydropteridin-4(1H)-one chemical structure, C7H11N5O, CAS 79493-89-3
(7S)-2-Amino-7-methyl-5,6,7,8-tetrahydropteridin-4(1H)-one
CAS 79493-89-3C7H11N5O
2,6-Dimethyl-5,6,7,8-tetrahydropteridin-4(1H)-one chemical structure, C8H12N4O, CAS 81138-95-6
2,6-Dimethyl-5,6,7,8-tetrahydropteridin-4(1H)-one
CAS 81138-95-6C8H12N4O
2-Amino-8-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridine-6-carbonitrile chemical structure, C8H10N6O, CAS 63954-42-7
2-Amino-8-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridine-6-carbonitrile
CAS 63954-42-7C8H10N6O
(S)-2-Amino-6-((S)-2-hydroxypropanoyl)-5,6,7,8-tetrahydropteridin-4(3H)-one chemical structure, C9H13N5O3, CAS 1488516-70-6
(S)-2-Amino-6-((S)-2-hydroxypropanoyl)-5,6,7,8-tetrahydropteridin-4(3H)-one
CAS 1488516-70-6C9H13N5O3
Cis-2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4(1H)-one xhydrochloride chemical structure, C8H14ClN5O, CAS 66547-54-4
Cis-2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4(1H)-one xhydrochloride
CAS 66547-54-4C8H14ClN5O
(6s)-5,6,7,8-Tetrahydro-l-biopterin sulfate chemical structure, C9H17N5O7S, CAS 2743427-62-3
(6s)-5,6,7,8-Tetrahydro-l-biopterin sulfate
CAS 2743427-62-3C9H17N5O7S
(6R,7S)-2-Amino-6,7-dimethyl-4-oxo-4,6,7,8-tetrahydropteridine-5(1H)-carbaldehyde chemical structure, C9H13N5O2, CAS 56527-18-5
(6R,7S)-2-Amino-6,7-dimethyl-4-oxo-4,6,7,8-tetrahydropteridine-5(1H)-carbaldehyde
CAS 56527-18-5C9H13N5O2
2-Amino-6-(aminomethyl)-5,6,7,8-tetrahydro-6,7-dimethyl-4(3H)-pteridinone chemical structure, C9H16N6O, CAS 52407-69-9
2-Amino-6-(aminomethyl)-5,6,7,8-tetrahydro-6,7-dimethyl-4(3H)-pteridinone
CAS 52407-69-9C9H16N6O
5,6-Dihydrodeoxysepiapterin dihydrochloride chemical structure, C9H15Cl2N5O2, CAS 69347-45-1
5,6-Dihydrodeoxysepiapterin dihydrochloride
CAS 69347-45-1C9H15Cl2N5O2
2-Amino-5,6,7,8-tetrahydro-4(1H)pteridinone Hydrochloride chemical structure, C6H10ClN5O, CAS 5752-25-0
2-Amino-5,6,7,8-tetrahydro-4(1H)pteridinone Hydrochloride
CAS 5752-25-0C6H10ClN5O
N-Nitroso-sapropterin-2 chemical structure, C9H14N6O4, CAS 1355024-07-5
N-Nitroso-sapropterin-2
CAS 1355024-07-5C9H14N6O4
(6S)-Tetrahydrobiopterin dihydrochloride chemical structure, C9H17Cl2N5O3, CAS 69056-39-9
(6S)-Tetrahydrobiopterin dihydrochloride
CAS 69056-39-9C9H17Cl2N5O3
Tetrahydropterin bis-Hydrochloride chemical structure, C6H11Cl2N5O
Tetrahydropterin bis-Hydrochloride
C6H11Cl2N5O