CompoundList
Sign in
Murcko scaffold

Benzylidenephthalide scaffold

62 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
62
With full pages
11
Scaffold SMILES

O=C1OC(=Cc2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Benzylidenephthalide page
Murcko scaffold O=C1OC(=Cc2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

Benzylidenephthalide chemical structure, C15H10O2, CAS 575-61-1
Benzylidenephthalide
CAS 575-61-1C15H10O2
3-(4-Chlorobenzal)phthalide chemical structure, C15H9ClO2, CAS 20526-97-0
3-(4-Chlorobenzal)phthalide
CAS 20526-97-0C15H9ClO2
3-(4-Methoxybenzylidene)phthalide chemical structure, C16H12O3, CAS 1286101-71-0
3-(4-Methoxybenzylidene)phthalide
CAS 1286101-71-0C16H12O3
3-(4-Fluorobenzylidene)phthalide chemical structure, C15H9FO2, CAS 2558-18-1
3-(4-Fluorobenzylidene)phthalide
CAS 2558-18-1C15H9FO2
5-Hydroxy-3-[(4-hydroxyphenyl)methylene]isobenzofuran-1(3H)-one chemical structure, C15H10O4, CAS 56783-95-0
5-Hydroxy-3-[(4-hydroxyphenyl)methylene]isobenzofuran-1(3H)-one
CAS 56783-95-0C15H10O4
Benzalphthalide, (Z)- chemical structure, C15H10O2, CAS 4767-56-0
Benzalphthalide, (Z)-
CAS 4767-56-0C15H10O2
2-(3-Oxo-2-benzofuran-1-ylidene)-2-phenylacetic acid chemical structure, C16H10O4
2-(3-Oxo-2-benzofuran-1-ylidene)-2-phenylacetic acid
C16H10O4
4-Fluorobenzylidenephthalide chemical structure, C15H9FO2, CAS 105279-30-9
4-Fluorobenzylidenephthalide
CAS 105279-30-9C15H9FO2
3-((4-Methoxyphenyl)methylene)phthalide chemical structure, C16H12O3, CAS 4767-61-7
3-((4-Methoxyphenyl)methylene)phthalide
CAS 4767-61-7C16H12O3
Benzalphthalide, (E)- chemical structure, C15H10O2, CAS 4767-55-9
Benzalphthalide, (E)-
CAS 4767-55-9C15H10O2
(3Z)-3-[(4-Ethylphenyl)-nitromethylidene]-2-benzofuran-1-one chemical structure, C17H13NO4, CAS 30516-61-1
(3Z)-3-[(4-Ethylphenyl)-nitromethylidene]-2-benzofuran-1-one
CAS 30516-61-1C17H13NO4
(3E)-3-[Nitro-(2,4,5-trimethylphenyl)methylidene]-2-benzofuran-1-one chemical structure, C18H15NO4, CAS 300388-71-0
(3E)-3-[Nitro-(2,4,5-trimethylphenyl)methylidene]-2-benzofuran-1-one
CAS 300388-71-0C18H15NO4
(3-Oxo-2-benzofuran-1(3H)-ylidene)(phenyl)acetic acid chemical structure, C16H10O4, CAS 61658-91-1
(3-Oxo-2-benzofuran-1(3H)-ylidene)(phenyl)acetic acid
CAS 61658-91-1C16H10O4
(E)-2-(3-Oxoisobenzofuran-1(3H)-ylidene)-2-phenylacetic acid chemical structure, C16H10O4, CAS 183968-09-4
(E)-2-(3-Oxoisobenzofuran-1(3H)-ylidene)-2-phenylacetic acid
CAS 183968-09-4C16H10O4
(3E)-3-[[4-Hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]-2-benzofuran-1-one chemical structure, C21H22O3, CAS 69574-11-4
(3E)-3-[[4-Hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]-2-benzofuran-1-one
CAS 69574-11-4C21H22O3
3-Benzylidene-6-nitro-2-benzofuran-1(3H)-one chemical structure, C15H9NO4, CAS 15298-16-5
3-Benzylidene-6-nitro-2-benzofuran-1(3H)-one
CAS 15298-16-5C15H9NO4
3-(3,4-Dichlorobenzylidene)-2-benzofuran-1(3H)-one chemical structure, C15H8Cl2O2, CAS 63964-47-6
3-(3,4-Dichlorobenzylidene)-2-benzofuran-1(3H)-one
CAS 63964-47-6C15H8Cl2O2
1(3H)-Isobenzofuranone, 3-[(4-nitrophenyl)methylene]- chemical structure, C15H9NO4, CAS 27695-16-5
1(3H)-Isobenzofuranone, 3-[(4-nitrophenyl)methylene]-
CAS 27695-16-5C15H9NO4
(Z)-3-(2,4-Dichlorobenzylidene)isobenzofuran-1(3H)-one chemical structure, C15H8Cl2O2, CAS 42086-72-6
(Z)-3-(2,4-Dichlorobenzylidene)isobenzofuran-1(3H)-one
CAS 42086-72-6C15H8Cl2O2
(3E)-3-[(3,5-Diethyl-4-hydroxyphenyl)methylidene]-2-benzofuran-1-one chemical structure, C19H18O3, CAS 69574-10-3
(3E)-3-[(3,5-Diethyl-4-hydroxyphenyl)methylidene]-2-benzofuran-1-one
CAS 69574-10-3C19H18O3
(3E)-3-[(2-Methylphenyl)-nitromethylidene]-2-benzofuran-1-one chemical structure, C16H11NO4, CAS 304446-20-6
(3E)-3-[(2-Methylphenyl)-nitromethylidene]-2-benzofuran-1-one
CAS 304446-20-6C16H11NO4
1(3H)-Isobenzofuranone, 3-[(3,4-dimethoxyphenyl)methylene]- chemical structure, C17H14O4, CAS 10001-30-6
1(3H)-Isobenzofuranone, 3-[(3,4-dimethoxyphenyl)methylene]-
CAS 10001-30-6C17H14O4
1(3H)-Isobenzofuranone, 3-[(2-methylphenyl)methylene]- chemical structure, C16H12O2, CAS 19391-29-8
1(3H)-Isobenzofuranone, 3-[(2-methylphenyl)methylene]-
CAS 19391-29-8C16H12O2
1(3H)-Isobenzofuranone, 3-[(4-methylphenyl)methylene]- chemical structure, C16H12O2, CAS 27695-13-2
1(3H)-Isobenzofuranone, 3-[(4-methylphenyl)methylene]-
CAS 27695-13-2C16H12O2