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Murcko scaffold

1-Phenyl-1,2,3,4-tetrahydronaphthalene scaffold

179 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
179
With full pages
37
Scaffold SMILES

c1ccc(C2CCCc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-1,2,3,4-tetrahydronaphthalene page
Murcko scaffold c1ccc(C2CCCc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 179 of 179 chemicals

(5S,6R,7R)-5-(4-Hydroxy-3-methoxyphenyl)-6,7-bis(hydroxymethyl)-5,6,7,8-tetrahydronaphthalene-2,3-diol chemical structure, C19H22O6
(5S,6R,7R)-5-(4-Hydroxy-3-methoxyphenyl)-6,7-bis(hydroxymethyl)-5,6,7,8-tetrahydronaphthalene-2,3-diol
C19H22O6
N-Hydroxy sertraline chemical structure, C17H17Cl2NO, CAS 124345-07-9
N-Hydroxy sertraline
CAS 124345-07-9C17H17Cl2NO
N-[(2R,4S)-4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl]propanamide chemical structure, C19H21NO, CAS 620170-79-8
N-[(2R,4S)-4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl]propanamide
CAS 620170-79-8C19H21NO
(1R,2R)-1-(4-Chloro-3-methoxyphenyl)-N-(2,2-dimethoxyethyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine chemical structure, C22H28ClNO3, CAS 169106-13-2
(1R,2R)-1-(4-Chloro-3-methoxyphenyl)-N-(2,2-dimethoxyethyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine
CAS 169106-13-2C22H28ClNO3
(1R,2S)-1-(4-Chloro-3-methoxyphenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine chemical structure, C18H20ClNO, CAS 169249-14-3
(1R,2S)-1-(4-Chloro-3-methoxyphenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine
CAS 169249-14-3C18H20ClNO
(5S,8S)-5-(3,4-Dichlorophenyl)-5,6,7,8-tetrahydro-8-(methylamino)-2-naphthalenemethanamine chemical structure, C18H20Cl2N2, CAS 711601-69-3
(5S,8S)-5-(3,4-Dichlorophenyl)-5,6,7,8-tetrahydro-8-(methylamino)-2-naphthalenemethanamine
CAS 711601-69-3C18H20Cl2N2
1-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-ol chemical structure, C16H14Cl2O, CAS 1498236-91-1
1-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-ol
CAS 1498236-91-1C16H14Cl2O
1-[4-(Trifluoromethyl)phenyl]-3,4-dihydro-2H-naphthalen-1-ol chemical structure, C17H15F3O, CAS 1309854-42-9
1-[4-(Trifluoromethyl)phenyl]-3,4-dihydro-2H-naphthalen-1-ol
CAS 1309854-42-9C17H15F3O
1-Naphthaleneacetic acid, 6-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1,2,3,4-tetrahydro-1-phenyl-, ethyl ester chemical structure, C26H36O3Si, CAS 1415611-12-9
1-Naphthaleneacetic acid, 6-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1,2,3,4-tetrahydro-1-phenyl-, ethyl ester
CAS 1415611-12-9C26H36O3Si
1-Naphthalenol, 6-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1,2,3,4-tetrahydro-1-phenyl- chemical structure, C22H30O2Si, CAS 1415611-11-8
1-Naphthalenol, 6-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1,2,3,4-tetrahydro-1-phenyl-
CAS 1415611-11-8C22H30O2Si
rac-cis-2,3-Dichloro Sertraline Hydrochloride chemical structure, C17H18Cl3N, CAS 1198084-29-5
rac-cis-2,3-Dichloro Sertraline Hydrochloride
CAS 1198084-29-5C17H18Cl3N
(1S,4R)-4-(2,3-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine chemical structure, C17H17Cl2N, CAS 2184053-08-3
(1S,4R)-4-(2,3-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
CAS 2184053-08-3C17H17Cl2N
Sertraline-N-methylacetamide chemical structure, C19H19Cl2NO, CAS 1413642-93-9
Sertraline-N-methylacetamide
CAS 1413642-93-9C19H19Cl2NO
(1S,4S)-7-(Chloromethyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine chemical structure, C18H18Cl3N, CAS 291306-37-1
(1S,4S)-7-(Chloromethyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine
CAS 291306-37-1C18H18Cl3N
rac-trans-3-Dechloro Sertraline Hydrochloride chemical structure, C17H19Cl2N, CAS 79896-35-8
rac-trans-3-Dechloro Sertraline Hydrochloride
CAS 79896-35-8C17H19Cl2N
(1R,4R)-N-Desmethyl sertraline hydrochloride chemical structure, C16H16Cl3N, CAS 675126-09-7
(1R,4R)-N-Desmethyl sertraline hydrochloride
CAS 675126-09-7C16H16Cl3N
Sertraline impurity 65 (mixture of enantiomers) chemical structure, C17H18Cl3N, CAS 2124277-88-7
Sertraline impurity 65 (mixture of enantiomers)
CAS 2124277-88-7C17H18Cl3N
4,4-Dimethyl-1-phenyl-1,2,3,4-tetrahydronaphthalen-1-ol chemical structure, C18H20O, CAS 58978-26-0
4,4-Dimethyl-1-phenyl-1,2,3,4-tetrahydronaphthalen-1-ol
CAS 58978-26-0C18H20O
7-(2-Methylpropyl)-1-(4-(2-methylpropyl)phenyl)-1,2,3,4-tetrahydronaphthalene-1,4-dicarboxylic acid chemical structure, C26H32O4, CAS 1391054-15-1
7-(2-Methylpropyl)-1-(4-(2-methylpropyl)phenyl)-1,2,3,4-tetrahydronaphthalene-1,4-dicarboxylic acid
CAS 1391054-15-1C26H32O4
rac-trans-N-Methyl Sertraline-d6 Hydrochloride chemical structure, C18H20Cl3N, CAS 2124272-18-8
rac-trans-N-Methyl Sertraline-d6 Hydrochloride
CAS 2124272-18-8C18H20Cl3N
rac-Trans Sertraline-d3 Hydrochloride chemical structure, C17H18Cl3N, CAS 1426174-06-2
rac-Trans Sertraline-d3 Hydrochloride
CAS 1426174-06-2C17H18Cl3N
(R)-Nafenopin chemical structure, C20H22O3, CAS 32147-36-7
(R)-Nafenopin
CAS 32147-36-7C20H22O3
(S)-Nafenopin chemical structure, C20H22O3, CAS 32147-37-8
(S)-Nafenopin
CAS 32147-37-8C20H22O3
(Rac,anti)-4-deschloro-sertraline chemical structure, C17H18ClN, CAS 871838-58-3
(Rac,anti)-4-deschloro-sertraline
CAS 871838-58-3C17H18ClN