Murcko scaffold
Ring system with 2 rings and 18 atoms
443 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 443
- With full pages
- 33
Scaffold SMILES
O=S(=O)(NN=Cc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 443 chemicals
![N-[(4-Dimethylaminophenyl)methylideneamino]-4-nitro-benzenesulfonamide chemical structure, C15H16N4O4S, CAS 6289-98-1](/s/FUYAFPMYOGQEIR-UHFFFAOYSA-N.svg)
N-[(4-Dimethylaminophenyl)methylideneamino]-4-nitro-benzenesulfonamide
CAS 6289-98-1C15H16N4O4S
![N-[(2-Ethoxyphenyl)methylideneamino]-4-nitro-benzenesulfonamide chemical structure, C15H15N3O5S, CAS 5450-25-9](/s/YLYDEZBGUCZTTN-UHFFFAOYSA-N.svg)
N-[(2-Ethoxyphenyl)methylideneamino]-4-nitro-benzenesulfonamide
CAS 5450-25-9C15H15N3O5S
![4-Aminobenzenesulfonic acid 2-[(3,4-dichlorophenyl)methylene]hydrazide chemical structure, C13H11Cl2N3O2S, CAS 5450-87-3](/s/QFMOKNQAVPOGOF-UHFFFAOYSA-N.svg)
4-Aminobenzenesulfonic acid 2-[(3,4-dichlorophenyl)methylene]hydrazide
CAS 5450-87-3C13H11Cl2N3O2S
4-Amino-N-(benzylideneamino)benzenesulfonamide
CAS 5448-70-4C13H13N3O2S
![4-Amino-N-[(4-methoxyphenyl)methylideneamino]benzenesulfonamide chemical structure, C14H15N3O3S, CAS 6335-09-7](/s/PTMGWNBTVCITAX-UHFFFAOYSA-N.svg)
4-Amino-N-[(4-methoxyphenyl)methylideneamino]benzenesulfonamide
CAS 6335-09-7C14H15N3O3S
![Benzenesulfonic acid,4-(acetylamino)-, 2-[(3-nitrophenyl)methylene]hydrazide chemical structure, C15H14N4O5S, CAS 5448-82-8](/s/AGMKHRRKRQIKKJ-UHFFFAOYSA-N.svg)
Benzenesulfonic acid,4-(acetylamino)-, 2-[(3-nitrophenyl)methylene]hydrazide
CAS 5448-82-8C15H14N4O5S
![4-Amino-N-[1-(4-methylphenyl)ethylideneamino]benzenesulfonamide chemical structure, C15H17N3O2S, CAS 5462-41-9](/s/NJZFOUCNWGZNLR-UHFFFAOYSA-N.svg)
4-Amino-N-[1-(4-methylphenyl)ethylideneamino]benzenesulfonamide
CAS 5462-41-9C15H17N3O2S
Benzenesulfonic acid,4-amino-, 2-(1-phenylpropylidene)hydrazide
C15H17N3O2S
![4-Amino-N-[1-(2,4-dimethylphenyl)ethylideneamino]benzenesulfonamide chemical structure, C16H19N3O2S, CAS 5448-95-3](/s/JBKLEZDKJKJHGZ-UHFFFAOYSA-N.svg)
4-Amino-N-[1-(2,4-dimethylphenyl)ethylideneamino]benzenesulfonamide
CAS 5448-95-3C16H19N3O2S
![N-[4-[[1-(4-Methylphenyl)ethylideneamino]sulfamoyl]phenyl]acetamide chemical structure, C17H19N3O3S, CAS 5448-96-4](/s/RBAWGWZPLCMLNX-UHFFFAOYSA-N.svg)
N-[4-[[1-(4-Methylphenyl)ethylideneamino]sulfamoyl]phenyl]acetamide
CAS 5448-96-4C17H19N3O3S
![4-Amino-N-[(2-ethoxyphenyl)methylideneamino]benzenesulfonamide chemical structure, C15H17N3O3S](/s/WCIIQTNQKLXGKU-UHFFFAOYSA-N.svg)
4-Amino-N-[(2-ethoxyphenyl)methylideneamino]benzenesulfonamide
C15H17N3O3S
![N-[4-[[1-(2,4-Dimethylphenyl)ethylideneamino]sulfamoyl]phenyl]acetamide chemical structure, C18H21N3O3S, CAS 5432-75-7](/s/SUBRYHGNRPFHSZ-UHFFFAOYSA-N.svg)
N-[4-[[1-(2,4-Dimethylphenyl)ethylideneamino]sulfamoyl]phenyl]acetamide
CAS 5432-75-7C18H21N3O3S
4-Methyl-N'-(1-phenylethylidene)benzene-1-sulfonohydrazide
CAS 4545-21-5C15H16N2O2S
![N-[4-[[(4-Methylphenyl)sulfonylhydrazinylidene]methyl]phenyl]acetamide chemical structure, C16H17N3O3S](/s/NGMKRGVLFSGKIJ-UHFFFAOYSA-N.svg)
N-[4-[[(4-Methylphenyl)sulfonylhydrazinylidene]methyl]phenyl]acetamide
C16H17N3O3S
![N-[[Dimethoxyphosphoryl(phenyl)methylidene]amino]-4-methylbenzenesulfonamide chemical structure, C16H19N2O5PS, CAS 28447-23-6](/s/AERFIKUZZQYUPT-UHFFFAOYSA-N.svg)
N-[[Dimethoxyphosphoryl(phenyl)methylidene]amino]-4-methylbenzenesulfonamide
CAS 28447-23-6C16H19N2O5PS
![N'-[(2-Hydroxy-3,5-diiodophenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide chemical structure, C14H12I2N2O3S, CAS 88848-00-4](/s/JWDZHJMUZDGPHP-UHFFFAOYSA-N.svg)
N'-[(2-Hydroxy-3,5-diiodophenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide
CAS 88848-00-4C14H12I2N2O3S
![N-[(2-Bromo-1-phenyl-ethylidene)amino]-2,4,6-trimethyl-benzenesulfonamide chemical structure, C17H19BrN2O2S, CAS 85487-86-1](/s/LZGFUZQBPREBLV-UHFFFAOYSA-N.svg)
N-[(2-Bromo-1-phenyl-ethylidene)amino]-2,4,6-trimethyl-benzenesulfonamide
CAS 85487-86-1C17H19BrN2O2S
![Benzenesulfonic acid, 2-[1-(4-methoxyphenyl)propylidene]hydrazide chemical structure, C16H18N2O3S, CAS 541520-14-3](/s/PCIMYIABYLXYAJ-UHFFFAOYSA-N.svg)
Benzenesulfonic acid, 2-[1-(4-methoxyphenyl)propylidene]hydrazide
CAS 541520-14-3C16H18N2O3S
![4-Methylbenzenesulfonic acid 2-[[3-(1-methylethoxy)phenyl]methylene]hydrazide chemical structure, C17H20N2O3S, CAS 495383-08-9](/s/ZRTMXORSDOOFSK-UHFFFAOYSA-N.svg)
4-Methylbenzenesulfonic acid 2-[[3-(1-methylethoxy)phenyl]methylene]hydrazide
CAS 495383-08-9C17H20N2O3S
![4-Chlorobenzenesulfonic acid 2-[(2-chloro-6-fluorophenyl)methylene]hydrazide chemical structure, C13H9Cl2FN2O2S, CAS 549483-40-1](/s/FEZZNCVKHNHFSU-UHFFFAOYSA-N.svg)
4-Chlorobenzenesulfonic acid 2-[(2-chloro-6-fluorophenyl)methylene]hydrazide
CAS 549483-40-1C13H9Cl2FN2O2S
![N-[(2-Hydroxy-3-methoxyphenyl)methylideneamino]benzenesulfonamide chemical structure, C14H14N2O4S](/s/CTRFBFOBDACYGZ-UHFFFAOYSA-N.svg)
N-[(2-Hydroxy-3-methoxyphenyl)methylideneamino]benzenesulfonamide
C14H14N2O4S
(Z)-N'-(3-Bromo-5-ethoxy-4-hydroxybenzylidene)-2,5-dichlorobenzenesulfonohydrazide
CAS 514836-21-6C15H13BrCl2N2O4S
![2,5-Dichloro-N-[(Z)-(2-propan-2-yloxyphenyl)methylideneamino]benzenesulfonamide chemical structure, C16H16Cl2N2O3S, CAS 515120-80-6](/s/CZMDVJPRBMJIQD-UHFFFAOYSA-N.svg)
2,5-Dichloro-N-[(Z)-(2-propan-2-yloxyphenyl)methylideneamino]benzenesulfonamide
CAS 515120-80-6C16H16Cl2N2O3S
![Benzoic acid, 2-(acetylamino)-5-[[(phenylmethylene)hydrazino]sulfonyl]- chemical structure, C16H15N3O5S, CAS 330856-59-2](/s/WAQUWHJCIHEJSC-UHFFFAOYSA-N.svg)
Benzoic acid, 2-(acetylamino)-5-[[(phenylmethylene)hydrazino]sulfonyl]-
CAS 330856-59-2C16H15N3O5S
- 4-(1,1-Dimethylethyl)benzenesulfonic acid 2-[[4-(dimethylamino)phenyl]methylene]hydrazide433328-83-7C19H25N3O2S
- 2,5-Dichloro-N-[(Z)-(4-prop-2-enoxyphenyl)methylideneamino]benzenesulfonamide515120-96-4C16H14Cl2N2O3S
- 4-Bromo-N-[(4-fluorophenyl)methylideneamino]benzenesulfonamide6355-24-4C13H10BrFN2O2S
- 4-Chlorobenzenesulfonic acid 2-(1-phenylpentylidene)hydrazide303139-50-6C17H19ClN2O2S
- Valerophenone tosylhydrazoneC18H22N2O2S
- 4-Bromobenzenesulfonic acid 2-[1-(4-methoxyphenyl)propylidene]hydrazide540791-01-3C16H17BrN2O3S
- 4-Fluorobenzenesulfonic acid 2-[(3-bromo-4,5-diethoxyphenyl)methylene]hydrazide588681-53-2C17H18BrFN2O4S
- 4-Chlorobenzenesulfonic acid 2-[(4-bromophenyl)methylene]hydrazide574009-99-7C13H10BrClN2O2S
- 4-Chlorobenzenesulfonic acid 2-(3-methyl-1-phenylbutylidene)hydrazide573993-85-8C17H19ClN2O2S
- N'-(4-Methoxybenzylidene)-4-methylbenzenesulfonohydrazide19350-72-2C15H16N2O3S
- N'-[1-(4-Chlorophenyl)ethylidene]-4-methoxybenzenesulfonohydrazide97728-84-2C15H15ClN2O3S
- 2-Nitrobenzaldehyde tosylhydrazone58809-90-8C14H13N3O4S
- N'-[(E)-(2-Methoxyphenyl)methylidene]benzenesulfonohydrazide145260-32-8C14H14N2O3S
- N'-(2,3-Dichlorobenzylidene)benzenesulfonohydrazide111316-05-3C13H10Cl2N2O2S
- 4-Chloro-N-[(E)-(3-nitrophenyl)methylideneamino]benzenesulfonamide5230-11-5C13H10ClN3O4S
- 4-Methyl-N'-(4-nitrobenzylidene)benzenesulfonohydrazide1747-50-8C14H13N3O4S
- N'-(3-Methoxybenzylidene)-4-methylbenzenesulfonohydrazide19350-71-1C15H16N2O3S
- N'-[(E)-(4-Nitrophenyl)methylidene]benzenesulfonohydrazide50626-29-4C13H11N3O4S
- P-Tolualdehyde P-tosylhydrazone40739-81-9C15H16N2O2S
- N'-[(E)-(4-Bromophenyl)methylidene]benzenesulfonohydrazide2383046-46-4C13H11BrN2O2S
- N-[(E)-(4-Propan-2-ylphenyl)methylideneamino]benzenesulfonamide5604-94-4C16H18N2O2S
- N-[(E)-(3-Methylphenyl)methylideneamino]benzenesulfonamide5616-94-4C14H14N2O2S
- 4-Chloro-N-[(E)-(4-methoxyphenyl)methylideneamino]benzenesulfonamide351471-88-0C14H13ClN2O3S
- 4-Chloro-N-[(E)-(3-prop-2-enoxyphenyl)methylideneamino]benzenesulfonamide351505-67-4C16H15ClN2O3S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=S(=O)(NCCc1ccccc1)c1ccccc183 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
O=C(CSc1ccccc1)Nc1ccccc177 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals