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Murcko scaffold

5,8-Dihydro-6H-pyrano[3,4-b]pyridine scaffold

37 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
37
With full pages
7
Scaffold SMILES

c1cnc2c(c1)CCOC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,8-Dihydro-6H-pyrano[3,4-b]pyridine page
Murcko scaffold c1cnc2c(c1)CCOC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

2-Amino-6,6-dimethyl-5,8-dihydro-6H-pyrano(3,4-b)pyridine-3-carboxylic acid chemical structure, C11H14N2O3, CAS 494776-07-7
2-Amino-6,6-dimethyl-5,8-dihydro-6H-pyrano(3,4-b)pyridine-3-carboxylic acid
CAS 494776-07-7C11H14N2O3
5,8-Dihydro-6H-pyrano[3,4-b]pyridine chemical structure, C8H9NO, CAS 126473-99-2
5,8-Dihydro-6H-pyrano[3,4-b]pyridine
CAS 126473-99-2C8H9NO
5H,6H,8H-Pyrano[3,4-b]pyridine-3-carboxylic acid chemical structure, C9H9NO3, CAS 1367947-69-0
5H,6H,8H-Pyrano[3,4-b]pyridine-3-carboxylic acid
CAS 1367947-69-0C9H9NO3
2-Chloro-5H,6H,8H-pyrano[3,4-b]pyridine-3-carbonitrile chemical structure, C9H7ClN2O, CAS 1510951-43-5
2-Chloro-5H,6H,8H-pyrano[3,4-b]pyridine-3-carbonitrile
CAS 1510951-43-5C9H7ClN2O
2-Chloro-5H,6H,8H-pyrano[3,4-b]pyridine-3-carboxylic acid chemical structure, C9H8ClNO3, CAS 1521702-51-1
2-Chloro-5H,6H,8H-pyrano[3,4-b]pyridine-3-carboxylic acid
CAS 1521702-51-1C9H8ClNO3
2-Chloro-5H,6H,8H-pyrano[3,4-b]pyridine chemical structure, C8H8ClNO, CAS 1552532-92-9
2-Chloro-5H,6H,8H-pyrano[3,4-b]pyridine
CAS 1552532-92-9C8H8ClNO
3-Bromo-6,8-dihydro-5H-pyrano[3,4-b]pyridin-5-amine chemical structure, C8H9BrN2O, CAS 2091157-36-5
3-Bromo-6,8-dihydro-5H-pyrano[3,4-b]pyridin-5-amine
CAS 2091157-36-5C8H9BrN2O
2,4-Dichloro-6,8-dihydro-5H-pyrano[3,4-b]pyridine chemical structure, C8H7Cl2NO, CAS 2214278-86-9
2,4-Dichloro-6,8-dihydro-5H-pyrano[3,4-b]pyridine
CAS 2214278-86-9C8H7Cl2NO
Ethyl 4-chloro-6,8-dihydro-5H-pyrano[3,4-b]pyridine-2-carboxylate chemical structure, C11H12ClNO3, CAS 2214278-88-1
Ethyl 4-chloro-6,8-dihydro-5H-pyrano[3,4-b]pyridine-2-carboxylate
CAS 2214278-88-1C11H12ClNO3
4-Chloro-6,8-dihydro-5H-pyrano[3,4-b]pyridine chemical structure, C8H8ClNO, CAS 2306443-77-4
4-Chloro-6,8-dihydro-5H-pyrano[3,4-b]pyridine
CAS 2306443-77-4C8H8ClNO
5H,6H,8H-Pyrano[3,4-b]pyridine-2-carboxylic acid chemical structure, C9H9NO3, CAS 2414325-04-3
5H,6H,8H-Pyrano[3,4-b]pyridine-2-carboxylic acid
CAS 2414325-04-3C9H9NO3
5H,6H,8H-Pyrano[3,4-b]pyridin-2-amine chemical structure, C8H10N2O, CAS 2168129-73-3
5H,6H,8H-Pyrano[3,4-b]pyridin-2-amine
CAS 2168129-73-3C8H10N2O
6,8-Dihydro-5H-pyrano[3,4-b]pyridin-5-amine chemical structure, C8H10N2O, CAS 2766511-84-4
6,8-Dihydro-5H-pyrano[3,4-b]pyridin-5-amine
CAS 2766511-84-4C8H10N2O
2-Fluoro-8,8-dimethyl-5,6-dihydropyrano[3,4-B]pyridine-3-carboxylic acid chemical structure, C11H12FNO3, CAS 2609742-35-8
2-Fluoro-8,8-dimethyl-5,6-dihydropyrano[3,4-B]pyridine-3-carboxylic acid
CAS 2609742-35-8C11H12FNO3
2-Fluoro-8,8-dimethyl-5,8-dihydro-6H-pyrano[3,4-B]pyridine chemical structure, C10H12FNO, CAS 2609742-34-7
2-Fluoro-8,8-dimethyl-5,8-dihydro-6H-pyrano[3,4-B]pyridine
CAS 2609742-34-7C10H12FNO
(S)-5-Fluoro-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid chemical structure, C10H10FNO3, CAS 2677884-82-9
(S)-5-Fluoro-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid
CAS 2677884-82-9C10H10FNO3
5-Fluoro-5-methyl-6,8-dihydropyrano[3,4-b]pyridine-3-carboxylic acid chemical structure, C10H10FNO3, CAS 2677884-80-7
5-Fluoro-5-methyl-6,8-dihydropyrano[3,4-b]pyridine-3-carboxylic acid
CAS 2677884-80-7C10H10FNO3
3-Bromo-5-methyl-6,8-dihydropyrano[3,4-b]pyridin-5-ol chemical structure, C9H10BrNO2, CAS 2677884-78-3
3-Bromo-5-methyl-6,8-dihydropyrano[3,4-b]pyridin-5-ol
CAS 2677884-78-3C9H10BrNO2
3-Bromo-5-fluoro-5-methyl-6,8-dihydropyrano[3,4-b]pyridine chemical structure, C9H9BrFNO, CAS 2677884-79-4
3-Bromo-5-fluoro-5-methyl-6,8-dihydropyrano[3,4-b]pyridine
CAS 2677884-79-4C9H9BrFNO
(R)-5-Cyano-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid chemical structure, C11H10N2O3, CAS 2677884-38-5
(R)-5-Cyano-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid
CAS 2677884-38-5C11H10N2O3
3-Bromo-5-methyl-6,8-dihydropyrano[3,4-b]pyridine-5-carbonitrile chemical structure, C10H9BrN2O, CAS 2677884-37-4
3-Bromo-5-methyl-6,8-dihydropyrano[3,4-b]pyridine-5-carbonitrile
CAS 2677884-37-4C10H9BrN2O
(R)-5-Fluoro-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid chemical structure, C10H10FNO3, CAS 2677884-81-8
(R)-5-Fluoro-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid
CAS 2677884-81-8C10H10FNO3
(S)-5-Cyano-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid chemical structure, C11H10N2O3, CAS 2677884-39-6
(S)-5-Cyano-5-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine-3-carboxylic acid
CAS 2677884-39-6C11H10N2O3
2-Bromo-N-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridin-5-amine chemical structure, C9H11BrN2O, CAS 2814522-92-2
2-Bromo-N-methyl-5,8-dihydro-6H-pyrano[3,4-b]pyridin-5-amine
CAS 2814522-92-2C9H11BrN2O