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Murcko scaffold

Ring system with 2 rings and 9 atoms

28 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
28
With full pages
5
Scaffold SMILES

c1ccc2c(c1)CO[IH]2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CO[IH]2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

1-Bromo-5-methyl-3,3-bis(trifluoromethyl)-1lambda3,2-benziodoxole chemical structure, C10H6BrF6IO, CAS 69352-00-7
1-Bromo-5-methyl-3,3-bis(trifluoromethyl)-1lambda3,2-benziodoxole
CAS 69352-00-7C10H6BrF6IO
1-Chloro-1,3-dihydro-5-methyl-3,3-bis(trifluoromethyl)-1,2-benziodoxole chemical structure, C10H6ClF6IO, CAS 69352-01-8
1-Chloro-1,3-dihydro-5-methyl-3,3-bis(trifluoromethyl)-1,2-benziodoxole
CAS 69352-01-8C10H6ClF6IO
3,3-Dimethyl-1lambda~3~,2-benziodoxol-1(3H)-ol chemical structure, C9H11IO2, CAS 69429-70-5
3,3-Dimethyl-1lambda~3~,2-benziodoxol-1(3H)-ol
CAS 69429-70-5C9H11IO2
1-Chloro-3,3-bis(trifluoromethyl)-1,3-dihydro-1lambda~3~,2-benziodoxole chemical structure, C9H4ClF6IO, CAS 76215-48-0
1-Chloro-3,3-bis(trifluoromethyl)-1,3-dihydro-1lambda~3~,2-benziodoxole
CAS 76215-48-0C9H4ClF6IO
1-[2-(Triisopropylsilyl)ethynyl]-3,3-bis(trifluoromethyl)-1,2-benziodoxole chemical structure, C20H25F6IOSi, CAS 181934-34-9
1-[2-(Triisopropylsilyl)ethynyl]-3,3-bis(trifluoromethyl)-1,2-benziodoxole
CAS 181934-34-9C20H25F6IOSi
1-Chloro-3,3-dimethyl-1,3-dihydro-1lambda~3~,2-benziodoxole chemical structure, C9H10ClIO, CAS 69352-04-1
1-Chloro-3,3-dimethyl-1,3-dihydro-1lambda~3~,2-benziodoxole
CAS 69352-04-1C9H10ClIO
[3,3-Dimethyl-1,2-benziodoxol-1(3H)-yl] azide chemical structure, C9H10IN3O, CAS 175786-57-9
[3,3-Dimethyl-1,2-benziodoxol-1(3H)-yl] azide
CAS 175786-57-9C9H10IN3O
3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole chemical structure, C10H10F3IO, CAS 887144-97-0
3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
CAS 887144-97-0C10H10F3IO
1,3,3-Tris(trifluoromethyl)-1,2-benziodoxole chemical structure, C10H4F9IO, CAS 887144-99-2
1,3,3-Tris(trifluoromethyl)-1,2-benziodoxole
CAS 887144-99-2C10H4F9IO
1-Fluoro-3,3-dimethyl-1,2-benziodoxole chemical structure, C9H10FIO, CAS 1391728-13-4
1-Fluoro-3,3-dimethyl-1,2-benziodoxole
CAS 1391728-13-4C9H10FIO
1,2-Benziodoxole, 1-(acetyloxy)-3,3-bis(trifluoromethyl)- chemical structure, C11H7F6IO3, CAS 887144-95-8
1,2-Benziodoxole, 1-(acetyloxy)-3,3-bis(trifluoromethyl)-
CAS 887144-95-8C11H7F6IO3
1,2-Benziodoxole, 5-methyl-1,3,3-tris(trifluoromethyl)- chemical structure, C11H6F9IO, CAS 887145-00-8
1,2-Benziodoxole, 5-methyl-1,3,3-tris(trifluoromethyl)-
CAS 887145-00-8C11H6F9IO
1-Cyano-3,3-dimethylbenziodoxole chemical structure, C10H10INO, CAS 172876-97-0
1-Cyano-3,3-dimethylbenziodoxole
CAS 172876-97-0C10H10INO
Acetic acid, 3,3-dimethyl-1,2-benziodoxol-1(3H)-yl ester chemical structure, C11H13IO3, CAS 175786-58-0
Acetic acid, 3,3-dimethyl-1,2-benziodoxol-1(3H)-yl ester
CAS 175786-58-0C11H13IO3
Alcohol C2F5-Togni reagent chemical structure, C11H10F5IO, CAS 1640118-52-0
Alcohol C2F5-Togni reagent
CAS 1640118-52-0C11H10F5IO
1-(Perfluorooctyl)-3,3-dimethyl-1,2-benziodoxole chemical structure, C17H10F17IO, CAS 2227490-56-2
1-(Perfluorooctyl)-3,3-dimethyl-1,2-benziodoxole
CAS 2227490-56-2C17H10F17IO
Alcohol C6F13-Togni reagent chemical structure, C15H10F13IO, CAS 2093262-90-7
Alcohol C6F13-Togni reagent
CAS 2093262-90-7C15H10F13IO
Alcohol C3F7-Togni reagent chemical structure, C12H10F7IO, CAS 2227490-54-0
Alcohol C3F7-Togni reagent
CAS 2227490-54-0C12H10F7IO
3H-1,2-Benziodoxole, 5-bromo-3,3-dimethyl-1-(trifluoromethyl)- chemical structure, C10H9BrF3IO, CAS 1888292-84-9
3H-1,2-Benziodoxole, 5-bromo-3,3-dimethyl-1-(trifluoromethyl)-
CAS 1888292-84-9C10H9BrF3IO
3H-1,2-Benziodoxole-5-carbonitrile, 3,3-dimethyl-1-(trifluoromethyl)- chemical structure, C11H9F3INO, CAS 1888292-86-1
3H-1,2-Benziodoxole-5-carbonitrile, 3,3-dimethyl-1-(trifluoromethyl)-
CAS 1888292-86-1C11H9F3INO
3H-1,2-Benziodoxole, 5-chloro-3,3-dimethyl-1-(trifluoromethyl)- chemical structure, C10H9ClF3IO, CAS 1888292-83-8
3H-1,2-Benziodoxole, 5-chloro-3,3-dimethyl-1-(trifluoromethyl)-
CAS 1888292-83-8C10H9ClF3IO
3H-1,2-Benziodoxole, 3,3-dimethyl-1,5-bis(trifluoromethyl)- chemical structure, C11H9F6IO, CAS 1888292-85-0
3H-1,2-Benziodoxole, 3,3-dimethyl-1,5-bis(trifluoromethyl)-
CAS 1888292-85-0C11H9F6IO
3H-1,2-Benziodoxole, 3,3-dimethyl-5-nitro-1-(trifluoromethyl)- chemical structure, C10H9F3INO3, CAS 1888292-87-2
3H-1,2-Benziodoxole, 3,3-dimethyl-5-nitro-1-(trifluoromethyl)-
CAS 1888292-87-2C10H9F3INO3
3H-1,2-Benziodoxole, 5-fluoro-3,3-dimethyl-1-(trifluoromethyl)- chemical structure, C10H9F4IO, CAS 1888292-82-7
3H-1,2-Benziodoxole, 5-fluoro-3,3-dimethyl-1-(trifluoromethyl)-
CAS 1888292-82-7C10H9F4IO