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Murcko scaffold

Tryptamide scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
16
With full pages
3
Scaffold SMILES

O=C(NCCc1c[nH]c2ccccc12)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Tryptamide page
Murcko scaffold O=C(NCCc1c[nH]c2ccccc12)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Tryptamide chemical structure, C16H15N3O, CAS 29876-14-0
Tryptamide
CAS 29876-14-0C16H15N3O
Nicotinamide, N-(2-(5-methoxyindol-3-yl)ethyl)- chemical structure, C17H17N3O2, CAS 29745-42-4
Nicotinamide, N-(2-(5-methoxyindol-3-yl)ethyl)-
CAS 29745-42-4C17H17N3O2
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]pyridine-3-carboxamide chemical structure, C16H14ClN3O, CAS 775290-76-1
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]pyridine-3-carboxamide
CAS 775290-76-1C16H14ClN3O
2-Ethoxy-N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide chemical structure, C18H19N3O2, CAS 794540-20-8
2-Ethoxy-N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide
CAS 794540-20-8C18H19N3O2
Nicotinamide, N-(2-(2-methyl-3-indolyl)ethyl)- chemical structure, C17H17N3O, CAS 63183-55-1
Nicotinamide, N-(2-(2-methyl-3-indolyl)ethyl)-
CAS 63183-55-1C17H17N3O
6-Chloro-N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide chemical structure, C16H14ClN3O, CAS 726155-33-5
6-Chloro-N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide
CAS 726155-33-5C16H14ClN3O
N-[2-(1H-Indol-3-yl)ethyl]-1-methylpyridin-1-ium-3-carboxamide iodide chemical structure, C17H18IN3O, CAS 59547-48-7
N-[2-(1H-Indol-3-yl)ethyl]-1-methylpyridin-1-ium-3-carboxamide iodide
CAS 59547-48-7C17H18IN3O
N-[2-(1H-Indol-3-yl)ethyl]-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C17H17N3OS, CAS 923882-79-5
N-[2-(1H-Indol-3-yl)ethyl]-2-(methylsulfanyl)pyridine-3-carboxamide
CAS 923882-79-5C17H17N3OS
5-Bromo-N~3~-[2-(5-fluoro-1H-indol-3-yl)ethyl]nicotinamide chemical structure, C16H13BrFN3O, CAS 920445-40-5
5-Bromo-N~3~-[2-(5-fluoro-1H-indol-3-yl)ethyl]nicotinamide
CAS 920445-40-5C16H13BrFN3O
5-Bromo-N~3~-[2-(5-chloro-1H-indol-3-yl)ethyl]nicotinamide chemical structure, C16H13BrClN3O, CAS 929866-66-0
5-Bromo-N~3~-[2-(5-chloro-1H-indol-3-yl)ethyl]nicotinamide
CAS 929866-66-0C16H13BrClN3O
Methyl (2R)-2-[(6-chloropyridin-3-yl)formamido]-3-(1H-indol-3-yl)propanoate chemical structure, C18H16ClN3O3, CAS 1212204-25-5
Methyl (2R)-2-[(6-chloropyridin-3-yl)formamido]-3-(1H-indol-3-yl)propanoate
CAS 1212204-25-5C18H16ClN3O3
N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]pyridine-3-carboxamide chemical structure, C16H15N3O2, CAS 140174-50-1
N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]pyridine-3-carboxamide
CAS 140174-50-1C16H15N3O2
N-[2-(5-Bromo-1H-indol-3-yl)ethyl]-2-chloropyridine-3-carboxamide chemical structure, C16H13BrClN3O, CAS 920506-36-1
N-[2-(5-Bromo-1H-indol-3-yl)ethyl]-2-chloropyridine-3-carboxamide
CAS 920506-36-1C16H13BrClN3O
2-Chloro-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]pyridine-3-carboxamide chemical structure, C16H14ClN3O2, CAS 920506-35-0
2-Chloro-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]pyridine-3-carboxamide
CAS 920506-35-0C16H14ClN3O2
2-Chloro-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]pyridine-3-carboxamide chemical structure, C17H16ClN3O2, CAS 920506-34-9
2-Chloro-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]pyridine-3-carboxamide
CAS 920506-34-9C17H16ClN3O2
(2R)-2-[(2-Chloropyridin-3-yl)formamido]-3-(1H-indol-3-yl)propanoic acid chemical structure, C17H14ClN3O3, CAS 1608725-28-5
(2R)-2-[(2-Chloropyridin-3-yl)formamido]-3-(1H-indol-3-yl)propanoic acid
CAS 1608725-28-5C17H14ClN3O3