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Murcko scaffold

Ring system with 3 rings and 26 atoms

72 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
72
With full pages
0
Scaffold SMILES

O=C(Cn1nc(C(=O)Nc2ccccc2)ccc1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1nc(C(=O)Nc2ccccc2)ccc1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 72 of 72 chemicals

N-(4-Methoxyphenyl)-6-oxo-1-({[4-(trifluoromethyl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H17F3N4O4, CAS 920391-04-4
N-(4-Methoxyphenyl)-6-oxo-1-({[4-(trifluoromethyl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide
CAS 920391-04-4C21H17F3N4O4
1-{[(4-Chlorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C20H17ClN4O4, CAS 920249-37-2
1-{[(4-Chlorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920249-37-2C20H17ClN4O4
1-{[(4-Fluorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C20H17FN4O4, CAS 920367-18-6
1-{[(4-Fluorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920367-18-6C20H17FN4O4
N-(4-Methoxyphenyl)-6-oxo-1-({[4-(trifluoromethoxy)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H17F3N4O5, CAS 920392-27-4
N-(4-Methoxyphenyl)-6-oxo-1-({[4-(trifluoromethoxy)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide
CAS 920392-27-4C21H17F3N4O5
1-{[(2,4-Dimethoxyphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C22H22N4O6, CAS 920248-75-5
1-{[(2,4-Dimethoxyphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920248-75-5C22H22N4O6
N-(4-Methoxyphenyl)-6-oxo-1-({[3-(trifluoromethyl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H17F3N4O4, CAS 920156-85-0
N-(4-Methoxyphenyl)-6-oxo-1-({[3-(trifluoromethyl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide
CAS 920156-85-0C21H17F3N4O4
1-{[(3-Fluorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C20H17FN4O4, CAS 920157-18-2
1-{[(3-Fluorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920157-18-2C20H17FN4O4
N-(4-Methoxyphenyl)-1-{[(3-methoxyphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H20N4O5, CAS 920366-97-8
N-(4-Methoxyphenyl)-1-{[(3-methoxyphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920366-97-8C21H20N4O5
N-(4-Methoxyphenyl)-6-oxo-1-({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H17F3N4O4, CAS 920366-90-1
N-(4-Methoxyphenyl)-6-oxo-1-({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide
CAS 920366-90-1C21H17F3N4O4
1-(2-((2-Chlorophenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C20H17ClN4O4, CAS 920157-54-6
1-(2-((2-Chlorophenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920157-54-6C20H17ClN4O4
1-{[(2-Fluorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C20H17FN4O4, CAS 920248-83-5
1-{[(2-Fluorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920248-83-5C20H17FN4O4
N-(4-Methoxyphenyl)-1-(2-((2-methoxyphenyl)amino)-2-oxoethyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H20N4O5, CAS 920248-71-1
N-(4-Methoxyphenyl)-1-(2-((2-methoxyphenyl)amino)-2-oxoethyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920248-71-1C21H20N4O5
1-{[(2,4-Dimethylphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C22H22N4O4, CAS 920248-67-5
1-{[(2,4-Dimethylphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920248-67-5C22H22N4O4
N-(4-Methoxyphenyl)-1-{[(4-methylphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H20N4O4, CAS 920390-89-2
N-(4-Methoxyphenyl)-1-{[(4-methylphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920390-89-2C21H20N4O4
N-(4-Methoxyphenyl)-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide chemical structure, C23H24N4O4, CAS 920157-27-3
N-(4-Methoxyphenyl)-6-oxo-1-({[4-(propan-2-yl)phenyl]carbamoyl}methyl)-1,6-dihydropyridazine-3-carboxamide
CAS 920157-27-3C23H24N4O4
N-(4-Methoxyphenyl)-1-{[(3-methylphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H20N4O4, CAS 920366-74-1
N-(4-Methoxyphenyl)-1-{[(3-methylphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920366-74-1C21H20N4O4
1-(2-((2,3-Dimethylphenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C22H22N4O4, CAS 920156-79-2
1-(2-((2,3-Dimethylphenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920156-79-2C22H22N4O4
N-(4-Methoxyphenyl)-1-{[(2-methylphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H20N4O4, CAS 920248-59-5
N-(4-Methoxyphenyl)-1-{[(2-methylphenyl)carbamoyl]methyl}-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920248-59-5C21H20N4O4
1-{[(4-Butylphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C24H26N4O4, CAS 920249-19-0
1-{[(4-Butylphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920249-19-0C24H26N4O4
1-(2-((4-Ethoxyphenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C22H22N4O5, CAS 920391-20-4
1-(2-((4-Ethoxyphenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920391-20-4C22H22N4O5
1-(2-((2-Ethoxyphenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C22H22N4O5, CAS 920156-91-8
1-(2-((2-Ethoxyphenyl)amino)-2-oxoethyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920156-91-8C22H22N4O5
1-{[(3-Chlorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C20H17ClN4O4, CAS 920157-45-5
1-{[(3-Chlorophenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920157-45-5C20H17ClN4O4
1-{[(3-Chloro-4-methylphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H19ClN4O4, CAS 920368-41-8
1-{[(3-Chloro-4-methylphenyl)carbamoyl]methyl}-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
CAS 920368-41-8C21H19ClN4O4
1-{[(3-Acetylphenyl)carbamoyl]methyl}-6-oxo-N-phenyl-1,6-dihydropyridazine-3-carboxamide chemical structure, C21H18N4O4, CAS 1171644-59-9
1-{[(3-Acetylphenyl)carbamoyl]methyl}-6-oxo-N-phenyl-1,6-dihydropyridazine-3-carboxamide
CAS 1171644-59-9C21H18N4O4