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Murcko scaffold

1-(Piperidin-4-yl)piperazine scaffold

163 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
163
With full pages
14
Scaffold SMILES

C1CC(N2CCNCC2)CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Piperidin-4-yl)piperazine page
Murcko scaffold C1CC(N2CCNCC2)CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 163 chemicals

1-Ethyl-4-(piperazin-1-yl)piperidine-4-carboxylic acid chemical structure, C12H23N3O2, CAS 898384-57-1
1-Ethyl-4-(piperazin-1-yl)piperidine-4-carboxylic acid
CAS 898384-57-1C12H23N3O2
1-Ethyl-4-(piperazin-1-yl)piperidine-4-carboxamide chemical structure, C12H24N4O, CAS 1184601-26-0
1-Ethyl-4-(piperazin-1-yl)piperidine-4-carboxamide
CAS 1184601-26-0C12H24N4O
4-(Piperazin-1-yl)-1-(propan-2-yl)piperidine-4-carboxamide chemical structure, C13H26N4O, CAS 1182980-35-3
4-(Piperazin-1-yl)-1-(propan-2-yl)piperidine-4-carboxamide
CAS 1182980-35-3C13H26N4O
1-Methyl-4-(4-piperidyl)piperazine Dihydrochloride chemical structure, C10H23Cl2N3, CAS 1219979-73-3
1-Methyl-4-(4-piperidyl)piperazine Dihydrochloride
CAS 1219979-73-3C10H23Cl2N3
2-[4-(4-Piperidinyl)-1-piperazinyl]-1-ethanol dihydrochloride chemical structure, C11H25Cl2N3O, CAS 1220035-51-7
2-[4-(4-Piperidinyl)-1-piperazinyl]-1-ethanol dihydrochloride
CAS 1220035-51-7C11H25Cl2N3O
Ethyl 1-methyl-4-(4-piperidinyl)-2-piperazinecarboxylate chemical structure, C13H25N3O2, CAS 688020-32-8
Ethyl 1-methyl-4-(4-piperidinyl)-2-piperazinecarboxylate
CAS 688020-32-8C13H25N3O2
Ethyl 4-methyl-1-(4-piperidinyl)-2-piperazinecarboxylate chemical structure, C13H25N3O2, CAS 688020-36-2
Ethyl 4-methyl-1-(4-piperidinyl)-2-piperazinecarboxylate
CAS 688020-36-2C13H25N3O2
4-(1-Methylpiperidin-4-yl)piperazine-2-carboxylic acid chemical structure, C11H21N3O2, CAS 1822511-54-5
4-(1-Methylpiperidin-4-yl)piperazine-2-carboxylic acid
CAS 1822511-54-5C11H21N3O2
Ethyl 4-(1-methyl-4-piperidinyl)-2-piperazinecarboxylate chemical structure, C13H25N3O2, CAS 688020-29-3
Ethyl 4-(1-methyl-4-piperidinyl)-2-piperazinecarboxylate
CAS 688020-29-3C13H25N3O2
Ethyl 1-(1-methyl-4-piperidinyl)-2-piperazinecarboxylate chemical structure, C13H25N3O2, CAS 688020-26-0
Ethyl 1-(1-methyl-4-piperidinyl)-2-piperazinecarboxylate
CAS 688020-26-0C13H25N3O2
2-(4-(1-Methylpiperidin-4-yl)piperazin-1-yl)acetic acid chemical structure, C12H23N3O2, CAS 1485738-05-3
2-(4-(1-Methylpiperidin-4-yl)piperazin-1-yl)acetic acid
CAS 1485738-05-3C12H23N3O2
1-(1,2,2,6,6-Pentamethyl-4-piperidinyl)piperazine chemical structure, C14H29N3, CAS 775287-94-0
1-(1,2,2,6,6-Pentamethyl-4-piperidinyl)piperazine
CAS 775287-94-0C14H29N3
1-(2-Fluoroethyl)-4-(4-piperidinyl)piperazine chemical structure, C11H22FN3, CAS 1089280-78-3
1-(2-Fluoroethyl)-4-(4-piperidinyl)piperazine
CAS 1089280-78-3C11H22FN3
M8Smm6jqx6 chemical structure, C15H29N3O2, CAS 2254146-74-0
M8Smm6jqx6
CAS 2254146-74-0C15H29N3O2
1-Methyl-4-(2-methylpiperidin-4-yl)piperazine chemical structure, C11H23N3, CAS 1601283-23-1
1-Methyl-4-(2-methylpiperidin-4-yl)piperazine
CAS 1601283-23-1C11H23N3
1-Methyl-4-(piperazin-1-yl)piperidine-4-carboxamide chemical structure, C11H22N4O, CAS 1179260-85-5
1-Methyl-4-(piperazin-1-yl)piperidine-4-carboxamide
CAS 1179260-85-5C11H22N4O
1-Methyl-4-(piperazin-1-yl)piperidine-4-carboxylic acid chemical structure, C11H21N3O2, CAS 898384-54-8
1-Methyl-4-(piperazin-1-yl)piperidine-4-carboxylic acid
CAS 898384-54-8C11H21N3O2
4-(Piperazin-1-yl)piperidine-4-carboxylic acid chemical structure, C10H19N3O2, CAS 1247083-01-7
4-(Piperazin-1-yl)piperidine-4-carboxylic acid
CAS 1247083-01-7C10H19N3O2
4-(Piperazin-1-yl)piperidine-4-carboxamide chemical structure, C10H20N4O, CAS 1251100-25-0
4-(Piperazin-1-yl)piperidine-4-carboxamide
CAS 1251100-25-0C10H20N4O
1-Methyl-4-(3-methylpiperidin-4-yl)piperazine chemical structure, C11H23N3, CAS 1339782-26-1
1-Methyl-4-(3-methylpiperidin-4-yl)piperazine
CAS 1339782-26-1C11H23N3
2-Methyl-1-(1-methylpiperidin-4-yl)piperazine chemical structure, C11H23N3, CAS 1267350-91-3
2-Methyl-1-(1-methylpiperidin-4-yl)piperazine
CAS 1267350-91-3C11H23N3
1-(1-Methylpiperidin-4-yl)piperazine-2-carboxylic acid chemical structure, C11H21N3O2, CAS 1484017-98-2
1-(1-Methylpiperidin-4-yl)piperazine-2-carboxylic acid
CAS 1484017-98-2C11H21N3O2
1-(Methylsulfonyl)-4-(4-piperidinyl)piperazine dihydrochloride chemical structure, C10H23Cl2N3O2S, CAS 1089282-83-6
1-(Methylsulfonyl)-4-(4-piperidinyl)piperazine dihydrochloride
CAS 1089282-83-6C10H23Cl2N3O2S
2-Methyl-1-(piperidin-4-yl)piperazine chemical structure, C10H21N3, CAS 1556309-62-6
2-Methyl-1-(piperidin-4-yl)piperazine
CAS 1556309-62-6C10H21N3