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Murcko scaffold

1-(Piperidin-4-yl)piperazine scaffold

163 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
163
With full pages
14
Scaffold SMILES

C1CC(N2CCNCC2)CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Piperidin-4-yl)piperazine page
Murcko scaffold C1CC(N2CCNCC2)CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 163 chemicals

1-Ethyl-4-piperidin-4-ylpiperazine chemical structure, C11H23N3, CAS 202991-77-3
1-Ethyl-4-piperidin-4-ylpiperazine
CAS 202991-77-3C11H23N3
1-(1-Methyl-4-piperidinyl)piperazine chemical structure, C10H21N3, CAS 23995-88-2
1-(1-Methyl-4-piperidinyl)piperazine
CAS 23995-88-2C10H21N3
Ethyl 4-(4-(ethylsulfonyl)piperazin-1-yl)piperidine-1-carboxylate chemical structure, C14H27N3O4S, CAS 462097-94-5
Ethyl 4-(4-(ethylsulfonyl)piperazin-1-yl)piperidine-1-carboxylate
CAS 462097-94-5C14H27N3O4S
1-Methyl-4-(1-methylpiperidin-4-yl)piperazine chemical structure, C11H23N3, CAS 36882-07-2
1-Methyl-4-(1-methylpiperidin-4-yl)piperazine
CAS 36882-07-2C11H23N3
1-Ethylsulfonyl-4-(1-propylpiperidin-4-yl)piperazine chemical structure, C14H29N3O2S, CAS 428846-40-6
1-Ethylsulfonyl-4-(1-propylpiperidin-4-yl)piperazine
CAS 428846-40-6C14H29N3O2S
1-(1-Propylpiperidin-4-yl)-4-propylsulfonylpiperazine chemical structure, C15H31N3O2S, CAS 428853-86-5
1-(1-Propylpiperidin-4-yl)-4-propylsulfonylpiperazine
CAS 428853-86-5C15H31N3O2S
1-Methylsulfonyl-4-(1-propylpiperidin-4-yl)piperazine chemical structure, C13H27N3O2S, CAS 428850-21-9
1-Methylsulfonyl-4-(1-propylpiperidin-4-yl)piperazine
CAS 428850-21-9C13H27N3O2S
Piperazine, 1-(1-ethyl-4-piperidinyl)-4-methyl-(9CI) chemical structure, C12H25N3, CAS 416861-95-5
Piperazine, 1-(1-ethyl-4-piperidinyl)-4-methyl-(9CI)
CAS 416861-95-5C12H25N3
Piperazine, 1-ethyl-4-(1-methyl-4-piperidinyl)-(9CI) chemical structure, C12H25N3, CAS 416867-23-7
Piperazine, 1-ethyl-4-(1-methyl-4-piperidinyl)-(9CI)
CAS 416867-23-7C12H25N3
1-Methyl-4-(piperidin-4-yl)piperazine chemical structure, C10H21N3, CAS 53617-36-0
1-Methyl-4-(piperidin-4-yl)piperazine
CAS 53617-36-0C10H21N3
2-[4-(1-Propan-2-ylpiperidin-4-yl)piperazin-1-yl]ethanol chemical structure, C14H29N3O, CAS 675141-56-7
2-[4-(1-Propan-2-ylpiperidin-4-yl)piperazin-1-yl]ethanol
CAS 675141-56-7C14H29N3O
Piperazine, 1-ethyl-4-(1-ethyl-4-piperidinyl)-(9CI) chemical structure, C13H27N3, CAS 415969-06-1
Piperazine, 1-ethyl-4-(1-ethyl-4-piperidinyl)-(9CI)
CAS 415969-06-1C13H27N3
1-Acetyl-4-(1-methyl-4-piperidinyl)piperazine chemical structure, C12H23N3O, CAS 416866-55-2
1-Acetyl-4-(1-methyl-4-piperidinyl)piperazine
CAS 416866-55-2C12H23N3O
1-Piperazinecarboxaldehyde,4-(1-ethyl-4-piperidinyl)-(9CI) chemical structure, C12H23N3O, CAS 416869-23-3
1-Piperazinecarboxaldehyde,4-(1-ethyl-4-piperidinyl)-(9CI)
CAS 416869-23-3C12H23N3O
2-{4-[1-(Butan-2-yl)piperidin-4-yl]piperazin-1-yl}ethanol chemical structure, C15H31N3O, CAS 675141-70-5
2-{4-[1-(Butan-2-yl)piperidin-4-yl]piperazin-1-yl}ethanol
CAS 675141-70-5C15H31N3O
2-(4-Piperidin-4-ylpiperazin-1-yl)ethanol chemical structure, C11H23N3O, CAS 884497-64-7
2-(4-Piperidin-4-ylpiperazin-1-yl)ethanol
CAS 884497-64-7C11H23N3O
1-(Piperidin-4-yl)piperazine chemical structure, C9H19N3, CAS 142013-66-9
1-(Piperidin-4-yl)piperazine
CAS 142013-66-9C9H19N3
tert-Butyl 4-(piperidin-4-yl)piperazine-1-carboxylate chemical structure, C14H27N3O2, CAS 205059-24-1
tert-Butyl 4-(piperidin-4-yl)piperazine-1-carboxylate
CAS 205059-24-1C14H27N3O2
tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate--hydrogen chloride (1/1) chemical structure, C14H28ClN3O2, CAS 205059-39-8
tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate--hydrogen chloride (1/1)
CAS 205059-39-8C14H28ClN3O2
tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate chemical structure, C14H27N3O2, CAS 177276-41-4
tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate
CAS 177276-41-4C14H27N3O2
(S)-tert-Butyl 4-methyl-4-(3-methylpiperazin-1-yl)piperidine-1-carboxylate chemical structure, C16H31N3O2, CAS 306296-78-6
(S)-tert-Butyl 4-methyl-4-(3-methylpiperazin-1-yl)piperidine-1-carboxylate
CAS 306296-78-6C16H31N3O2
1-(4-Piperidin-4-yl-piperazin-1-yl)-ethanone chemical structure, C11H21N3O, CAS 205059-37-6
1-(4-Piperidin-4-yl-piperazin-1-yl)-ethanone
CAS 205059-37-6C11H21N3O
1-(1-Ethylpiperidin-4-yl)piperazine chemical structure, C11H23N3, CAS 686298-05-5
1-(1-Ethylpiperidin-4-yl)piperazine
CAS 686298-05-5C11H23N3
tert-Butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate chemical structure, C15H29N3O2, CAS 190964-91-1
tert-Butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate
CAS 190964-91-1C15H29N3O2