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Murcko scaffold

Ring system with 2 rings and 11 atoms

37 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
37
With full pages
3
Scaffold SMILES

c1n[nH]cc1CN1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1n[nH]cc1CN1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

1-[(1-Methyl-1H-pyrazol-4-yl)methyl]-L-proline chemical structure, C10H15N3O2, CAS 1163303-99-8
1-[(1-Methyl-1H-pyrazol-4-yl)methyl]-L-proline
CAS 1163303-99-8C10H15N3O2
1-[(1,3-Dimethyl-1H-pyrazol-4-yl)methyl]-L-proline chemical structure, C11H17N3O2, CAS 1162114-89-7
1-[(1,3-Dimethyl-1H-pyrazol-4-yl)methyl]-L-proline
CAS 1162114-89-7C11H17N3O2
1-((1-Methyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-amine chemical structure, C9H16N4, CAS 1247243-26-0
1-((1-Methyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-amine
CAS 1247243-26-0C9H16N4
{2-[4-(Pyrrolidin-1-ylmethyl)-1H-pyrazol-1-yl]ethyl}amine chemical structure, C10H18N4, CAS 1447965-75-4
{2-[4-(Pyrrolidin-1-ylmethyl)-1H-pyrazol-1-yl]ethyl}amine
CAS 1447965-75-4C10H18N4
1-[(3-Methyl-1H-pyrazol-4-yl)methyl]-3-pyrrolidinamine chemical structure, C9H16N4, CAS 1229025-43-7
1-[(3-Methyl-1H-pyrazol-4-yl)methyl]-3-pyrrolidinamine
CAS 1229025-43-7C9H16N4
(1-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-yl)methanol chemical structure, C11H19N3O, CAS 1595557-80-4
(1-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-yl)methanol
CAS 1595557-80-4C11H19N3O
[(2S,4S)-4-Fluoro-1-[(1-methylpyrazol-4-yl)methyl]pyrrolidin-2-yl]methanamine chemical structure, C10H17FN4, CAS 1820575-42-5
[(2S,4S)-4-Fluoro-1-[(1-methylpyrazol-4-yl)methyl]pyrrolidin-2-yl]methanamine
CAS 1820575-42-5C10H17FN4
{[(2S,4S)-4-Fluoro-1-[(1-methyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]methyl}(methyl)amine chemical structure, C11H19FN4, CAS 1820579-84-7
{[(2S,4S)-4-Fluoro-1-[(1-methyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]methyl}(methyl)amine
CAS 1820579-84-7C11H19FN4
1-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)pyrrolidine-3-carboxylic acid chemical structure, C11H17N3O2, CAS 2097943-85-4
1-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)pyrrolidine-3-carboxylic acid
CAS 2097943-85-4C11H17N3O2
1-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-ol chemical structure, C10H17N3O, CAS 2097947-97-0
1-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-ol
CAS 2097947-97-0C10H17N3O
1-((1,3,5-Trimethyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-ol chemical structure, C11H19N3O, CAS 2092728-73-7
1-((1,3,5-Trimethyl-1H-pyrazol-4-yl)methyl)pyrrolidin-3-ol
CAS 2092728-73-7C11H19N3O
({4-Fluoro-1-[(1-methyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl}methyl)(methyl)amine chemical structure, C11H19FN4, CAS 1803567-48-7
({4-Fluoro-1-[(1-methyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl}methyl)(methyl)amine
CAS 1803567-48-7C11H19FN4
[4-Fluoro-1-[(1-methyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]methanamine chemical structure, C10H17FN4, CAS 1955530-99-0
[4-Fluoro-1-[(1-methyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]methanamine
CAS 1955530-99-0C10H17FN4
4-((3-Methylpyrrolidin-1-yl)methyl)-1H-pyrazole chemical structure, C9H15N3, CAS 1928811-26-0
4-((3-Methylpyrrolidin-1-yl)methyl)-1H-pyrazole
CAS 1928811-26-0C9H15N3
N-[[(2S,4S)-4-Fluoro-1-[(1-methylpyrazol-4-yl)methyl]pyrrolidin-2-yl]methyl]prop-2-enamide chemical structure, C13H19FN4O, CAS 2128674-35-9
N-[[(2S,4S)-4-Fluoro-1-[(1-methylpyrazol-4-yl)methyl]pyrrolidin-2-yl]methyl]prop-2-enamide
CAS 2128674-35-9C13H19FN4O
4-[(3-{[(tert-Butoxy)carbonyl]amino}pyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylic acid chemical structure, C15H24N4O4, CAS 2137619-24-8
4-[(3-{[(tert-Butoxy)carbonyl]amino}pyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylic acid
CAS 2137619-24-8C15H24N4O4
Lithium(1+) 4-[(3-hydroxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylate chemical structure, C10H14LiN3O3, CAS 2155855-89-1
Lithium(1+) 4-[(3-hydroxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylate
CAS 2155855-89-1C10H14LiN3O3
4-[(3-Hydroxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylic acid chemical structure, C10H15N3O3, CAS 2155855-88-0
4-[(3-Hydroxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylic acid
CAS 2155855-88-0C10H15N3O3
Lithium(1+) ion 4-[(3-methoxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylate chemical structure, C11H16LiN3O3, CAS 2155856-40-7
Lithium(1+) ion 4-[(3-methoxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylate
CAS 2155856-40-7C11H16LiN3O3
4-[(3-Methoxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylic acid chemical structure, C11H17N3O3, CAS 2155856-39-4
4-[(3-Methoxypyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxylic acid
CAS 2155856-39-4C11H17N3O3
Lithium(1+) ion 4-{[3-(dimethylamino)pyrrolidin-1-yl]methyl}-1-methyl-1H-pyrazole-3-carboxylate chemical structure, C12H19LiN4O2, CAS 2155852-78-9
Lithium(1+) ion 4-{[3-(dimethylamino)pyrrolidin-1-yl]methyl}-1-methyl-1H-pyrazole-3-carboxylate
CAS 2155852-78-9C12H19LiN4O2
4-{[3-(Dimethylamino)pyrrolidin-1-yl]methyl}-1-methyl-1H-pyrazole-3-carboxylic acid chemical structure, C12H20N4O2, CAS 2155852-77-8
4-{[3-(Dimethylamino)pyrrolidin-1-yl]methyl}-1-methyl-1H-pyrazole-3-carboxylic acid
CAS 2155852-77-8C12H20N4O2
4-[(3-Aminopyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxamide dihydrochloride chemical structure, C10H19Cl2N5O, CAS 2247107-95-3
4-[(3-Aminopyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxamide dihydrochloride
CAS 2247107-95-3C10H19Cl2N5O
4-[(3-Aminopyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C10H17N5O, CAS 2168995-67-1
4-[(3-Aminopyrrolidin-1-yl)methyl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 2168995-67-1C10H17N5O