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Murcko scaffold

Ring system with 2 rings and 15 atoms

15 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
15
With full pages
11
Scaffold SMILES

O=C(Nc1ccccc1)Nc1ccsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)Nc1ccsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

Methyl 3-[(3,4-dichlorophenyl)carbamoylamino]thiophene-2-carboxylate chemical structure, C13H10Cl2N2O3S, CAS 313386-36-6
Methyl 3-[(3,4-dichlorophenyl)carbamoylamino]thiophene-2-carboxylate
CAS 313386-36-6C13H10Cl2N2O3S
Methyl 3-{[(2,3-dichloroanilino)carbonyl]amino}-2-thiophenecarboxylate chemical structure, C13H10Cl2N2O3S, CAS 701930-52-1
Methyl 3-{[(2,3-dichloroanilino)carbonyl]amino}-2-thiophenecarboxylate
CAS 701930-52-1C13H10Cl2N2O3S
Methyl 3-({[2-(trifluoromethyl)anilino]carbonyl}amino)-2-thiophenecarboxylate chemical structure, C14H11F3N2O3S, CAS 353258-09-0
Methyl 3-({[2-(trifluoromethyl)anilino]carbonyl}amino)-2-thiophenecarboxylate
CAS 353258-09-0C14H11F3N2O3S
Methyl 3-[(anilinocarbonyl)amino]-4-methyl-2-thiophenecarboxylate chemical structure, C14H14N2O3S, CAS 478258-56-9
Methyl 3-[(anilinocarbonyl)amino]-4-methyl-2-thiophenecarboxylate
CAS 478258-56-9C14H14N2O3S
1-(2,6-Dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea chemical structure, C11H7Cl2N3O3S, CAS 672286-03-2
1-(2,6-Dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea
CAS 672286-03-2C11H7Cl2N3O3S
Methyl 3-{[(3-methylphenyl)carbamoyl]amino}thiophene-2-carboxylate chemical structure, C14H14N2O3S, CAS 894251-28-6
Methyl 3-{[(3-methylphenyl)carbamoyl]amino}thiophene-2-carboxylate
CAS 894251-28-6C14H14N2O3S
Methyl 3-{[(2-fluorophenyl)carbamoyl]amino}thiophene-2-carboxylate chemical structure, C13H11FN2O3S, CAS 890338-88-2
Methyl 3-{[(2-fluorophenyl)carbamoyl]amino}thiophene-2-carboxylate
CAS 890338-88-2C13H11FN2O3S
5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid methyl ester chemical structure, C18H22N2O3S, CAS 216573-01-2
5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid methyl ester
CAS 216573-01-2C18H22N2O3S
Methyl 3-{[(4-fluoroanilino)carbonyl]amino}-2-thiophenecarboxylate chemical structure, C13H11FN2O3S, CAS 353258-07-8
Methyl 3-{[(4-fluoroanilino)carbonyl]amino}-2-thiophenecarboxylate
CAS 353258-07-8C13H11FN2O3S
Methyl 3-{[(3-methoxyphenyl)carbamoyl]amino}thiophene-2-carboxylate chemical structure, C14H14N2O4S, CAS 901974-26-3
Methyl 3-{[(3-methoxyphenyl)carbamoyl]amino}thiophene-2-carboxylate
CAS 901974-26-3C14H14N2O4S
Methyl 3-{[(2,4-dimethoxyphenyl)carbamoyl]amino}thiophene-2-carboxylate chemical structure, C15H16N2O5S, CAS 894149-89-4
Methyl 3-{[(2,4-dimethoxyphenyl)carbamoyl]amino}thiophene-2-carboxylate
CAS 894149-89-4C15H16N2O5S
N-(2-Carbamoyl-5-tert-butyl-3-thienyl)-N'-(4-methylphenyl)urea chemical structure, C17H21N3O2S, CAS 371974-26-4
N-(2-Carbamoyl-5-tert-butyl-3-thienyl)-N'-(4-methylphenyl)urea
CAS 371974-26-4C17H21N3O2S
Methyl 3-{[(2-chlorophenyl)carbamoyl]amino}thiophene-2-carboxylate chemical structure, C13H11ClN2O3S, CAS 897322-94-0
Methyl 3-{[(2-chlorophenyl)carbamoyl]amino}thiophene-2-carboxylate
CAS 897322-94-0C13H11ClN2O3S
1-(5-tert-Butyl-thiophen-3-yl)-3-(2,3-dichloro-phenyl)-urea chemical structure, C15H16Cl2N2OS, CAS 227623-30-5
1-(5-tert-Butyl-thiophen-3-yl)-3-(2,3-dichloro-phenyl)-urea
CAS 227623-30-5C15H16Cl2N2OS
Methyl 3-{[(4-chlorophenyl)carbamoyl]amino}-4-methylthiophene-2-carboxylate chemical structure, C14H13ClN2O3S, CAS 1330750-57-6
Methyl 3-{[(4-chlorophenyl)carbamoyl]amino}-4-methylthiophene-2-carboxylate
CAS 1330750-57-6C14H13ClN2O3S