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Murcko scaffold

4-Oxa-7-azaspiro(2.5)octane scaffold

30 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
30
With full pages
3
Scaffold SMILES

C1COC2(CC2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Oxa-7-azaspiro(2.5)octane page
Murcko scaffold C1COC2(CC2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

4-Oxa-7-azaspiro(2.5)octane chemical structure, C6H11NO, CAS 220291-92-9
4-Oxa-7-azaspiro(2.5)octane
CAS 220291-92-9C6H11NO
4-Oxa-7-azaspiro[2.5]octane hydrochloride chemical structure, C6H12ClNO, CAS 1427195-23-0
4-Oxa-7-azaspiro[2.5]octane hydrochloride
CAS 1427195-23-0C6H12ClNO
5-Methyl-4-oxa-7-azaspiro[2.5]octane chemical structure, C7H13NO, CAS 1936550-49-0
5-Methyl-4-oxa-7-azaspiro[2.5]octane
CAS 1936550-49-0C7H13NO
6-Methyl-4-oxa-7-azaspiro[2.5]octane chemical structure, C7H13NO, CAS 2889368-52-7
6-Methyl-4-oxa-7-azaspiro[2.5]octane
CAS 2889368-52-7C7H13NO
7-[(tert-Butoxy)carbonyl]-4-oxa-7-azaspiro[2.5]octane-1-carboxylic acid chemical structure, C12H19NO5, CAS 1251002-65-9
7-[(tert-Butoxy)carbonyl]-4-oxa-7-azaspiro[2.5]octane-1-carboxylic acid
CAS 1251002-65-9C12H19NO5
tert-Butyl 1-amino-4-oxa-7-azaspiro[2.5]octane-7-carboxylate chemical structure, C11H20N2O3, CAS 1251011-33-2
tert-Butyl 1-amino-4-oxa-7-azaspiro[2.5]octane-7-carboxylate
CAS 1251011-33-2C11H20N2O3
(6S)-6-Methyl-4-oxa-7-azaspiro[2.5]octane chemical structure, C7H13NO, CAS 3064397-40-3
(6S)-6-Methyl-4-oxa-7-azaspiro[2.5]octane
CAS 3064397-40-3C7H13NO
(S)-8-Methyl-4-oxa-7-azaspiro[2.5]octane chemical structure, C7H13NO, CAS 2866468-85-9
(S)-8-Methyl-4-oxa-7-azaspiro[2.5]octane
CAS 2866468-85-9C7H13NO
(4-Oxa-7-azaspiro[2.5]octan-5-yl)methanol chemical structure, C7H13NO2, CAS 2366180-44-9
(4-Oxa-7-azaspiro[2.5]octan-5-yl)methanol
CAS 2366180-44-9C7H13NO2
1,1-Difluoro-4-oxa-7-azaspiro[2.5]octane chemical structure, C6H9F2NO, CAS 2825006-67-3
1,1-Difluoro-4-oxa-7-azaspiro[2.5]octane
CAS 2825006-67-3C6H9F2NO
Allyl 6-methoxy-4-oxa-7-azaspiro[2.5]octane-7-carboxylate chemical structure, C11H17NO4, CAS 2364588-64-5
Allyl 6-methoxy-4-oxa-7-azaspiro[2.5]octane-7-carboxylate
CAS 2364588-64-5C11H17NO4
4-Oxa-7-azaspiro[2.5]octan-7-amine chemical structure, C6H12N2O, CAS 2646592-71-2
4-Oxa-7-azaspiro[2.5]octan-7-amine
CAS 2646592-71-2C6H12N2O
7-Nitroso-4-oxa-7-azaspiro[2.5]octane chemical structure, C6H10N2O2, CAS 2646592-70-1
7-Nitroso-4-oxa-7-azaspiro[2.5]octane
CAS 2646592-70-1C6H10N2O2
tert-Butyl 4-oxa-7-azaspiro[2.5]octane-7-carboxylate chemical structure, C11H19NO3, CAS 2708287-44-7
tert-Butyl 4-oxa-7-azaspiro[2.5]octane-7-carboxylate
CAS 2708287-44-7C11H19NO3
4-Oxa-7-azaspiro[2.5]octan-5-ylmethanol hydrochloride chemical structure, C7H14ClNO2, CAS 2828021-02-7
4-Oxa-7-azaspiro[2.5]octan-5-ylmethanol hydrochloride
CAS 2828021-02-7C7H14ClNO2
1,1-Difluoro-4-oxa-7-azaspiro[2.5]octane-6-carboxylic acid chemical structure, C7H9F2NO3, CAS 2765271-37-0
1,1-Difluoro-4-oxa-7-azaspiro[2.5]octane-6-carboxylic acid
CAS 2765271-37-0C7H9F2NO3
(5S)-7-[(tert-Butoxy)carbonyl]-4-oxa-7-aZaspiro[2.5]octane-5-carboxylic acid chemical structure, C12H19NO5, CAS 2763753-47-3
(5S)-7-[(tert-Butoxy)carbonyl]-4-oxa-7-aZaspiro[2.5]octane-5-carboxylic acid
CAS 2763753-47-3C12H19NO5
tert-Butyl (5S)-5-(hydroxymethyl)-4-oxa-7-azaspiro[2.5]octane-7-carboxylate chemical structure, C12H21NO4, CAS 2763753-46-2
tert-Butyl (5S)-5-(hydroxymethyl)-4-oxa-7-azaspiro[2.5]octane-7-carboxylate
CAS 2763753-46-2C12H21NO4
1,1-Difluoro-4-oxa-7-azaspiro[2.5]octane hydrochloride chemical structure, C6H10ClF2NO, CAS 2825006-68-4
1,1-Difluoro-4-oxa-7-azaspiro[2.5]octane hydrochloride
CAS 2825006-68-4C6H10ClF2NO
Ethyl 4-oxa-7-azaspiro[2.5]octane-1-carboxylate chemical structure, C9H15NO3, CAS 2870702-50-2
Ethyl 4-oxa-7-azaspiro[2.5]octane-1-carboxylate
CAS 2870702-50-2C9H15NO3
(5R)-7-tert-Butoxycarbonyl-4-oxa-7-azaspiro[2.5]octane-5-carboxylic acid chemical structure, C12H19NO5, CAS 3085028-37-8
(5R)-7-tert-Butoxycarbonyl-4-oxa-7-azaspiro[2.5]octane-5-carboxylic acid
CAS 3085028-37-8C12H19NO5
6,8-Dimethyl-4-oxa-7-azaspiro[2.5]octane chemical structure, C8H15NO, CAS 2889368-54-9
6,8-Dimethyl-4-oxa-7-azaspiro[2.5]octane
CAS 2889368-54-9C8H15NO
Methyl 4-oxa-7-azaspiro[2.5]octane-1-carboxylate chemical structure, C8H13NO3, CAS 2913406-26-3
Methyl 4-oxa-7-azaspiro[2.5]octane-1-carboxylate
CAS 2913406-26-3C8H13NO3
7-Acetyl-4-oxa-7-azaspiro[2.5]octane-1-carboxylic acid chemical structure, C9H13NO4, CAS 2913404-85-8
7-Acetyl-4-oxa-7-azaspiro[2.5]octane-1-carboxylic acid
CAS 2913404-85-8C9H13NO4