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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 529 to 576 of 1,868 chemicals

1-(1,2-Thiazol-3-yl)ethan-1-one chemical structure, C5H5NOS, CAS 88511-35-7
1-(1,2-Thiazol-3-yl)ethan-1-one
CAS 88511-35-7C5H5NOS
N-Hydroxymethyl-3,4-dichloro-5-isothiazolecarboxamide chemical structure, C5H4Cl2N2O2S, CAS 352010-60-7
N-Hydroxymethyl-3,4-dichloro-5-isothiazolecarboxamide
CAS 352010-60-7C5H4Cl2N2O2S
2-(Isothiazol-3-yl)ethan-1-amine chemical structure, C5H8N2S, CAS 1368005-92-8
2-(Isothiazol-3-yl)ethan-1-amine
CAS 1368005-92-8C5H8N2S
4-Methyl-1,2-thiazole-3-carboxylic acid chemical structure, C5H5NO2S, CAS 1507952-32-0
4-Methyl-1,2-thiazole-3-carboxylic acid
CAS 1507952-32-0C5H5NO2S
(4-Methyl-1,2-thiazol-3-yl)methanol chemical structure, C5H7NOS, CAS 2168741-86-2
(4-Methyl-1,2-thiazol-3-yl)methanol
CAS 2168741-86-2C5H7NOS
Methyl 5-nitroisothiazole-3-carboxylate chemical structure, C5H4N2O4S, CAS 1094070-50-4
Methyl 5-nitroisothiazole-3-carboxylate
CAS 1094070-50-4C5H4N2O4S
5-Bromo-1,2-thiazole-3-carboxylic acid chemical structure, C4H2BrNO2S, CAS 4576-89-0
5-Bromo-1,2-thiazole-3-carboxylic acid
CAS 4576-89-0C4H2BrNO2S
1-(4-Bromo-1,2-thiazol-3-yl)ethan-1-one chemical structure, C5H4BrNOS, CAS 89283-97-6
1-(4-Bromo-1,2-thiazol-3-yl)ethan-1-one
CAS 89283-97-6C5H4BrNOS
N-Methoxy-N-methylisothiazole-5-carboxamide chemical structure, C6H8N2O2S, CAS 1044278-06-9
N-Methoxy-N-methylisothiazole-5-carboxamide
CAS 1044278-06-9C6H8N2O2S
5-Methyl-3-isothiazolecarbonitrile chemical structure, C5H4N2S, CAS 65735-08-2
5-Methyl-3-isothiazolecarbonitrile
CAS 65735-08-2C5H4N2S
5-(Bromomethyl)-1,2-thiazole chemical structure, C4H4BrNS, CAS 208837-85-8
5-(Bromomethyl)-1,2-thiazole
CAS 208837-85-8C4H4BrNS
5-{[(tert-Butoxy)carbonyl]amino}-3-methyl-1,2-thiazole-4-carboxylic acid chemical structure, C10H14N2O4S, CAS 1179765-94-6
5-{[(tert-Butoxy)carbonyl]amino}-3-methyl-1,2-thiazole-4-carboxylic acid
CAS 1179765-94-6C10H14N2O4S
5-Acetamido-3-methylisothiazole-4-carboxylic acid chemical structure, C7H8N2O3S, CAS 51674-31-8
5-Acetamido-3-methylisothiazole-4-carboxylic acid
CAS 51674-31-8C7H8N2O3S
3-Methyl-5-(2,2,2-trifluoroacetamido)isothiazole-4-carboxylic acid chemical structure, C7H5F3N2O3S, CAS 1179953-18-4
3-Methyl-5-(2,2,2-trifluoroacetamido)isothiazole-4-carboxylic acid
CAS 1179953-18-4C7H5F3N2O3S
3-Methyl-5-{[(prop-2-en-1-yloxy)carbonyl]amino}-1,2-thiazole-4-carboxylic acid chemical structure, C9H10N2O4S, CAS 1344043-32-8
3-Methyl-5-{[(prop-2-en-1-yloxy)carbonyl]amino}-1,2-thiazole-4-carboxylic acid
CAS 1344043-32-8C9H10N2O4S
Ethyl 2-amino-3-(isothiazol-5-yl)propanoate chemical structure, C8H12N2O2S, CAS 1378271-61-4
Ethyl 2-amino-3-(isothiazol-5-yl)propanoate
CAS 1378271-61-4C8H12N2O2S
4-Methyl-3-isothiazolecarbohydrazide chemical structure, C5H7N3OS, CAS 1254073-94-3
4-Methyl-3-isothiazolecarbohydrazide
CAS 1254073-94-3C5H7N3OS
Methyl 4-methyl-1,2-thiazole-3-carboxylate chemical structure, C6H7NO2S, CAS 64024-47-1
Methyl 4-methyl-1,2-thiazole-3-carboxylate
CAS 64024-47-1C6H7NO2S
4-Chloro-3-methyl-1,2-thiazole-5-sulfonamide chemical structure, C4H5ClN2O2S2, CAS 1235865-39-0
4-Chloro-3-methyl-1,2-thiazole-5-sulfonamide
CAS 1235865-39-0C4H5ClN2O2S2
Isothiazole-5-sulfinic acid chemical structure, C3H3NO2S2, CAS 2137915-97-8
Isothiazole-5-sulfinic acid
CAS 2137915-97-8C3H3NO2S2
5-(Tributylstannyl)isothiazole chemical structure, C15H29NSSn, CAS 1416853-22-9
5-(Tributylstannyl)isothiazole
CAS 1416853-22-9C15H29NSSn
5-Iodoisothiazole chemical structure, C3H2INS, CAS 49602-30-4
5-Iodoisothiazole
CAS 49602-30-4C3H2INS
2-(1,2-Thiazol-4-yl)ethan-1-ol chemical structure, C5H7NOS, CAS 1536667-54-5
2-(1,2-Thiazol-4-yl)ethan-1-ol
CAS 1536667-54-5C5H7NOS
5-Iodo-3-methyl-1,2-thiazole-4-carboxylic acid chemical structure, C5H4INO2S, CAS 1383546-18-6
5-Iodo-3-methyl-1,2-thiazole-4-carboxylic acid
CAS 1383546-18-6C5H4INO2S