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Murcko scaffold

2-[2-(Piperazin-1-yl)ethyl]-1H-1,3-benzodiazole scaffold

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
5
With full pages
4
Scaffold SMILES

c1ccc2[nH]c(CCN3CCNCC3)nc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[2-(Piperazin-1-yl)ethyl]-1H-1,3-benzodiazole page
Murcko scaffold c1ccc2[nH]c(CCN3CCNCC3)nc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-[1-Methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]propanamide chemical structure, C18H27N5O, CAS 896828-57-2
N-[1-Methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]propanamide
CAS 896828-57-2C18H27N5O
N-[1-Methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]acetamide chemical structure, C17H25N5O, CAS 899411-43-9
N-[1-Methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]acetamide
CAS 899411-43-9C17H25N5O
2-Methyl-N-[1-methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]propanamide chemical structure, C19H29N5O, CAS 896830-34-5
2-Methyl-N-[1-methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]propanamide
CAS 896830-34-5C19H29N5O
N-[1-Methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]pentanamide chemical structure, C20H31N5O, CAS 900258-96-0
N-[1-Methyl-2-[2-(4-methylpiperazin-1-yl)ethyl]benzimidazol-5-yl]pentanamide
CAS 900258-96-0C20H31N5O
2-[2-(Piperazin-1-yl)ethyl]-1H-1,3-benzodiazole chemical structure, C13H18N4, CAS 1369002-84-5
2-[2-(Piperazin-1-yl)ethyl]-1H-1,3-benzodiazole
CAS 1369002-84-5C13H18N4