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Murcko scaffold

Ring system with 4 rings and 24 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
4
With full pages
1
Scaffold SMILES

O=c1cc2[nH]n(-c3ccccc3)c(=O)c2cn1Cc1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc2[nH]n(-c3ccccc3)c(=O)c2cn1Cc1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Gkt-136901 chemical structure, C19H15ClN4O2, CAS 955272-06-7
Gkt-136901
CAS 955272-06-7C19H15ClN4O2
4-Methyl-2-(2-methylphenyl)-5-(pyridine-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione chemical structure, C20H18N4O2, CAS 1062624-71-8
4-Methyl-2-(2-methylphenyl)-5-(pyridine-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
CAS 1062624-71-8C20H18N4O2
2-(4-Fluorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione chemical structure, C19H15FN4O2, CAS 1010897-16-1
2-(4-Fluorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
CAS 1010897-16-1C19H15FN4O2
GKT136901 (hydrochloride) chemical structure, C19H16Cl2N4O2, CAS 1254507-01-1
GKT136901 (hydrochloride)
CAS 1254507-01-1C19H16Cl2N4O2