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Murcko scaffold

5-Phenoxy-2-phenyl-1H-isoindole-1,3(2H)-dione scaffold

69 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
69
With full pages
1
Scaffold SMILES

O=C1c2ccc(Oc3ccccc3)cc2C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenoxy-2-phenyl-1H-isoindole-1,3(2H)-dione page
Murcko scaffold O=C1c2ccc(Oc3ccccc3)cc2C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

5-(3-Aminophenoxy)-2-(4-hydroxyphenyl)-1H-isoindole-1,3(2H)-dione chemical structure, C20H14N2O4, CAS 351372-58-2
5-(3-Aminophenoxy)-2-(4-hydroxyphenyl)-1H-isoindole-1,3(2H)-dione
CAS 351372-58-2C20H14N2O4
5-(3-Aminophenoxy)-2-phenyl-1H-isoindole-1,3(2H)-dione chemical structure, C20H14N2O3, CAS 313521-21-0
5-(3-Aminophenoxy)-2-phenyl-1H-isoindole-1,3(2H)-dione
CAS 313521-21-0C20H14N2O3
5-(3-Aminophenoxy)-2-(2-methylphenyl)isoindole-1,3-dione chemical structure, C21H16N2O3, CAS 320368-67-0
5-(3-Aminophenoxy)-2-(2-methylphenyl)isoindole-1,3-dione
CAS 320368-67-0C21H16N2O3
5-(4-Aminophenoxy)-2-(4-methylphenyl)-1H-isoindole-1,3(2H)-dione chemical structure, C21H16N2O3, CAS 296796-57-1
5-(4-Aminophenoxy)-2-(4-methylphenyl)-1H-isoindole-1,3(2H)-dione
CAS 296796-57-1C21H16N2O3
Methyl 3-[5-(4-nitrophenoxy)-1,3-dioxoisoindol-2-yl]benzoate chemical structure, C22H14N2O7, CAS 294890-91-8
Methyl 3-[5-(4-nitrophenoxy)-1,3-dioxoisoindol-2-yl]benzoate
CAS 294890-91-8C22H14N2O7
2-(4-Acetylphenyl)-5-(3-nitrophenoxy)isoindole-1,3-dione chemical structure, C22H14N2O6, CAS 312746-98-8
2-(4-Acetylphenyl)-5-(3-nitrophenoxy)isoindole-1,3-dione
CAS 312746-98-8C22H14N2O6
4-{[2-(2-Hydroxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]oxy}benzoic acid chemical structure, C21H13NO6, CAS 296771-14-7
4-{[2-(2-Hydroxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]oxy}benzoic acid
CAS 296771-14-7C21H13NO6
3-[5-(4-Nitrophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]benzoic acid chemical structure, C21H12N2O7, CAS 305857-46-9
3-[5-(4-Nitrophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]benzoic acid
CAS 305857-46-9C21H12N2O7
3-[5-(3-Nitrophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]benzoic acid chemical structure, C21H12N2O7, CAS 330635-09-1
3-[5-(3-Nitrophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]benzoic acid
CAS 330635-09-1C21H12N2O7
[2-[5-(4-Acetamidophenoxy)-1,3-dioxoisoindol-2-yl]phenyl] acetate chemical structure, C24H18N2O6, CAS 331656-24-7
[2-[5-(4-Acetamidophenoxy)-1,3-dioxoisoindol-2-yl]phenyl] acetate
CAS 331656-24-7C24H18N2O6
RefChem:382062 chemical structure, C20H12N2O5, CAS 114026-04-9
RefChem:382062
CAS 114026-04-9C20H12N2O5
2-(3-Ethynylphenyl)-5-(3-nitrophenoxy)isoindole-1,3-dione chemical structure, C22H12N2O5, CAS 302927-65-7
2-(3-Ethynylphenyl)-5-(3-nitrophenoxy)isoindole-1,3-dione
CAS 302927-65-7C22H12N2O5
4-(1,3-Dioxo-5-phenoxy-1,3-dihydro-2H-isoindol-2-yl)benzoic acid chemical structure, C21H13NO5, CAS 312924-01-9
4-(1,3-Dioxo-5-phenoxy-1,3-dihydro-2H-isoindol-2-yl)benzoic acid
CAS 312924-01-9C21H13NO5
N-[3-[2-(2-Methylphenyl)-1,3-dioxoisoindol-5-yl]oxyphenyl]acetamide chemical structure, C23H18N2O4, CAS 330561-62-1
N-[3-[2-(2-Methylphenyl)-1,3-dioxoisoindol-5-yl]oxyphenyl]acetamide
CAS 330561-62-1C23H18N2O4
2-(3-Hydroxyphenyl)-5-(4-nitrophenoxy)-1H-isoindole-1,3(2H)-dione chemical structure, C20H12N2O6, CAS 305857-53-8
2-(3-Hydroxyphenyl)-5-(4-nitrophenoxy)-1H-isoindole-1,3(2H)-dione
CAS 305857-53-8C20H12N2O6
2-(4-Iodophenyl)-5-(4-nitrophenoxy)isoindole-1,3-dione chemical structure, C20H11IN2O5, CAS 328265-74-3
2-(4-Iodophenyl)-5-(4-nitrophenoxy)isoindole-1,3-dione
CAS 328265-74-3C20H11IN2O5
2-[5-({4-Nitrophenyl}oxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]phenyl acetate chemical structure, C22H14N2O7, CAS 331656-14-5
2-[5-({4-Nitrophenyl}oxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]phenyl acetate
CAS 331656-14-5C22H14N2O7
2-(2-Ethylphenyl)-5-(2-methoxyphenoxy)isoindole-1,3-dione chemical structure, C23H19NO4, CAS 516467-67-7
2-(2-Ethylphenyl)-5-(2-methoxyphenoxy)isoindole-1,3-dione
CAS 516467-67-7C23H19NO4
2-Oxopropyl 3-[5-(4-bromophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]benzoate chemical structure, C24H16BrNO6, CAS 433314-96-6
2-Oxopropyl 3-[5-(4-bromophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]benzoate
CAS 433314-96-6C24H16BrNO6
3-[5-(4-Chlorophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-4-methylbenzoic acid chemical structure, C22H14ClNO5, CAS 664976-09-4
3-[5-(4-Chlorophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-4-methylbenzoic acid
CAS 664976-09-4C22H14ClNO5
5-(4-Bromophenoxy)-2-(2,6-dimethylphenyl)-1H-isoindole-1,3(2H)-dione chemical structure, C22H16BrNO3, CAS 664975-01-3
5-(4-Bromophenoxy)-2-(2,6-dimethylphenyl)-1H-isoindole-1,3(2H)-dione
CAS 664975-01-3C22H16BrNO3
N-[4-[2-(4-Hydroxyphenyl)-1,3-dioxoisoindol-5-yl]oxyphenyl]acetamide chemical structure, C22H16N2O5, CAS 305359-59-5
N-[4-[2-(4-Hydroxyphenyl)-1,3-dioxoisoindol-5-yl]oxyphenyl]acetamide
CAS 305359-59-5C22H16N2O5
5-({3-[(1,3-Dioxo-2-phenyl-2,3-dihydro-1H-isoindol-5-yl)oxy]phenyl}amino)-5-oxopentanoic acid chemical structure, C25H20N2O6, CAS 305360-66-1
5-({3-[(1,3-Dioxo-2-phenyl-2,3-dihydro-1H-isoindol-5-yl)oxy]phenyl}amino)-5-oxopentanoic acid
CAS 305360-66-1C25H20N2O6
N-[3-(1,3-Dioxo-2-phenylisoindol-5-yl)oxyphenyl]propanamide chemical structure, C23H18N2O4, CAS 305360-60-5
N-[3-(1,3-Dioxo-2-phenylisoindol-5-yl)oxyphenyl]propanamide
CAS 305360-60-5C23H18N2O4