Murcko scaffold
2H-Pyran-2-one scaffold
510 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 510
- With full pages
- 70
Scaffold SMILES
O=c1cccco1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 510 chemicals
alpha-Pyrone-4,6-dicarboxylic acid
CAS 72698-24-9C7H4O6
Methyltriacetolactone
CAS 672-89-9C7H8O3
Mesitene lactone
CAS 675-09-2C7H8O2
6-n-Pentyl-2H-pyran-2-one
CAS 27593-23-3C10H14O2
3-Hydroxy-2H-pyran-2-one
CAS 496-64-0C5H4O3
Coumalic acid
CAS 500-05-0C6H4O4
2H-Pyran-2-one
CAS 504-31-4C5H4O2
Ethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate
CAS 3385-34-0C10H12O4
Methyl coumalate
CAS 6018-41-3C7H6O4
4,6-Dimethyl-5-formylpyran-2-one
CAS 480-65-9C8H8O4
Methyl 2-oxo-2H-pyran-3-carboxylate
CAS 25991-27-9C7H6O4
3-Bromo-5-carbethoxy-4,6-dimethyl-2-pyrone
CAS 18152-79-9C10H11BrO4
4-Methoxy-6-((1-butyl)heptyl)-2H-pyran-2-one
CAS 90632-47-6C17H28O3
Pyrenocine B
CAS 72674-29-4C11H14O5
(AlphaS)-alpha-amino-6-carboxy-2-oxo-2H-pyran-4-propanoic acid
CAS 15911-87-2C9H9NO6
2H-Pyran-2-one, 4-methyl-6-(1-methylethyl)-
CAS 50405-95-3C9H12O2
Stizolobinic acid
CAS 17388-96-4C9H9NO6
6-Ethyl-3-(2-methylpropyl)-2H-pyran-2-one
CAS 17654-99-8C11H16O2
Diethyl 6-methyl-2-oxo-2H-pyran-4-yl phosphate
CAS 26662-09-9C10H15O6P
2H-Pyran-5-carboxylic acid, 4,6-dimethyl-2-oxo-, methyl ester
CAS 41264-06-6C9H10O4
Chlamydospordiol
CAS 157998-92-0C11H16O5
2-Oxo-2H-pyran-6-carboxylic acid
CAS 672-67-3C6H4O4
Ethyl 4,6-dimethyl-3-nitro-2-oxo-2H-pyran-5-carboxylate
CAS 6272-87-3C10H11NO6
3,4,5,6-Tetrachloropyran-2-one
CAS 10269-62-2C5Cl4O2
- 6-Hydroxy-2-oxo-2H-pyran-4-yl acetate6630-34-8C7H6O5
- 6-Penta-1,3-diynylpyran-2-one20851-32-5C10H6O2
- 6-(Pent-1-yn-1-yl)-2H-pyran-2-one24203-77-8C10H10O2
- 6-(2-Oxopentyl)pyran-2-one24203-80-3C10H12O3
- Methyl 2-oxo-2H-pyran-6-carboxylate68160-93-0C7H6O4
- 6-Hydroxy-4-methyl-2H-pyran-2-one67116-20-5C6H6O3
- (4-Methoxy-2-oxo-2H-pyran-6-yl)acetic acid18068-85-4C8H8O5
- Propan-2-yl 2-oxo-2H-pyran-5-carboxylate61752-09-8C9H10O4
- (3Z)-3-(1-Hydroxyethylidene)-4-methyl-2H-pyran-2,6(3H)-dione7470-42-0C8H8O4
- Propyl 2,4-dimethyl-6-oxo-pyran-3-carboxylate7470-47-5C11H14O4
- Ethyl coumalate5942-96-1C8H8O4
- Ethyl 2-hydroxy-3-(4-methoxy-2-oxo-2H-pyran-6-yl)-2-propenoate18068-83-2C11H12O6
- 3-Propyl-6-[(4E,7E,10E,12E,18E)-3,15,17-trihydroxy-4,8,10,12,16,18-hexamethylicosa-4,7,10,12,18-pentaen-2-yl]pyran-2-one1215113-39-5C34H52O5
- Chloro-(6-oxo-2-pent-1-ynylpyran-3-yl)mercury24203-79-0C10H9ClHgO2
- Chloro-(6-oxo-2-penta-1,3-diynylpyran-3-yl)mercury23060-81-3C10H5ClHgO2
- Stizolobate3060-62-6C9H9NO6
- 4-Chloro-6-methyl-2H-pyran-2-one17422-72-9C6H5ClO2
- Methyl 6-methyl-2-oxo-2H-pyran-5-carboxylate669-40-9C8H8O4
- 2H-Pyran-2-one, 3-bromo-4-methoxy-6-methyl-670-35-9C7H7BrO3
- 2H-Pyran-2-one, 4-methoxy-6-methyl-3-nitro-54774-80-0C7H7NO5
- 6-(Diethylamino)-3,5-dimethyl-2H-pyran-2-one33259-29-9C11H17NO2
- 3-Methyl-2-oxo-2H-pyran-6-carboxylic acid3060-68-2C7H6O4
- 3,4,5,6-Tetramethyl-2H-pyran-2-one51595-76-7C9H12O2
- 4-Methoxy-6-(2-oxopropyl)pyran-2-one21179-76-0C9H10O4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
