Murcko scaffold
Ring system with 2 rings and 11 atoms
140 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 140
- With full pages
- 6
Scaffold SMILES
O=C(C1CC1)N1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 140 chemicals
1-Cyclopropanecarbonylpiperidin-4-amine
CAS 883106-47-6C9H16N2O
1-(Cyclopropylcarbonyl)-2-methyl-piperidine
CAS 560089-70-5C10H17NO
![1-[(2,2,3,3-Tetramethylcyclopropyl)carbonyl]piperidine chemical structure, C13H23NO, CAS 300382-66-5](/s/SBSJWKJHOPXTPL-UHFFFAOYSA-N.svg)
1-[(2,2,3,3-Tetramethylcyclopropyl)carbonyl]piperidine
CAS 300382-66-5C13H23NO
1-(Cyclopropylcarbonyl)piperidine-4-carboxylic acid
CAS 876866-50-1C10H15NO3
Cyclopropyl-(4-hydroxymethyl-piperidin-1-yl)-methanone
CAS 135136-14-0C10H17NO2
Ethyl 1-(cyclopropylcarbonyl)piperidine-4-carboxylate
CAS 135136-38-8C12H19NO3
1-(1-Piperidinylcarbonyl)cyclopropanecarbonitrile
CAS 546114-01-6C10H14N2O
1-Cyclopropanecarbonyl-4-hydroxypiperidine
CAS 130311-91-0C9H15NO2
![1-[(2-Methylcyclopropyl)carbonyl]-2-piperidinecarboxylic acid chemical structure, C11H17NO3, CAS 1032056-94-2](/s/PGKUSBLIDFWNGG-UHFFFAOYSA-N.svg)
1-[(2-Methylcyclopropyl)carbonyl]-2-piperidinecarboxylic acid
CAS 1032056-94-2C11H17NO3
1-(Cyclopropylcarbonyl)-3-piperidinecarboxylic acid
CAS 926198-16-5C10H15NO3
(4-Amino-1-piperidinyl)(2-methylcyclopropyl)methanone
CAS 926257-86-5C10H18N2O
1-(Cyclopropylcarbonyl)-2-piperidinecarboxylic acid
CAS 1103277-37-7C10H15NO3
1-(Cyclopropylcarbonyl)piperidin-3-amine
CAS 1114596-39-2C9H16N2O
2,2-Dimethyl-3-(piperidin-1-ylcarbonyl)-cyclopropanecarboxylic acid
CAS 1142215-00-6C12H19NO3
![3-{[4-(Ethoxycarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid chemical structure, C15H23NO5, CAS 1142215-11-9](/s/IMZHAKOCRWDNSO-UHFFFAOYSA-N.svg)
3-{[4-(Ethoxycarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid
CAS 1142215-11-9C15H23NO5
![3-{[3-(Ethoxycarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid chemical structure, C15H23NO5, CAS 1186647-30-2](/s/YHQVBIYAMICIEJ-UHFFFAOYSA-N.svg)
3-{[3-(Ethoxycarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid
CAS 1186647-30-2C15H23NO5
![3-[(4-Hydroxypiperidin-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid chemical structure, C12H19NO4, CAS 1142215-17-5](/s/WKEYDOIFIIWHHI-UHFFFAOYSA-N.svg)
3-[(4-Hydroxypiperidin-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid
CAS 1142215-17-5C12H19NO4
![3-{[4-(Aminocarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid chemical structure, C13H20N2O4, CAS 1142215-21-1](/s/FTRKXRUEJXZQHF-UHFFFAOYSA-N.svg)
3-{[4-(Aminocarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid
CAS 1142215-21-1C13H20N2O4
![3-{[3-(Aminocarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid chemical structure, C13H20N2O4, CAS 1186653-79-1](/s/RHLBCWMZENCYAI-UHFFFAOYSA-N.svg)
3-{[3-(Aminocarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid
CAS 1186653-79-1C13H20N2O4
![2,2-Dimethyl-3-[(2-methylpiperidin-1-yl)carbonyl]-cyclopropanecarboxylic acid chemical structure, C13H21NO3, CAS 1186653-96-2](/s/KGENRCCKPMOQGZ-UHFFFAOYSA-N.svg)
2,2-Dimethyl-3-[(2-methylpiperidin-1-yl)carbonyl]-cyclopropanecarboxylic acid
CAS 1186653-96-2C13H21NO3
![2,2-Dimethyl-3-[(3-methylpiperidin-1-yl)carbonyl]-cyclopropanecarboxylic acid chemical structure, C13H21NO3, CAS 1186654-05-6](/s/SOMJPPGYJWKMIA-UHFFFAOYSA-N.svg)
2,2-Dimethyl-3-[(3-methylpiperidin-1-yl)carbonyl]-cyclopropanecarboxylic acid
CAS 1186654-05-6C13H21NO3
![2,2-Dimethyl-3-[(4-methylpiperidin-1-yl)carbonyl]-cyclopropanecarboxylic acid chemical structure, C13H21NO3, CAS 1142215-23-3](/s/LGBUOOLBRZNYSG-UHFFFAOYSA-N.svg)
2,2-Dimethyl-3-[(4-methylpiperidin-1-yl)carbonyl]-cyclopropanecarboxylic acid
CAS 1142215-23-3C13H21NO3
1-Cyclopropanecarbonylpiperidine-4-carbaldehyde
CAS 1082446-73-8C10H15NO2
(4-Chloro-1-piperidinyl)cyclopropylmethanone
CAS 1082772-73-3C9H14ClNO
- (3R)-1-Cyclopropanecarbonylpiperidin-3-amine1704947-97-6C9H16N2O
- (S)-(3-Aminopiperidin-1-yl)(cyclopropyl)methanone2271926-81-7C9H16N2O
- 1-(Cyclopropylcarbonyl)-4-piperidinecarboxamide1092023-78-3C10H16N2O2
- 1 supplierstert-Butyl (1-(cyclopropanecarbonyl)piperidin-4-yl)carbamate1152430-26-6C14H24N2O3
- 1-(Cyclopropanecarbonyl)piperidine-4-carbonitrile1176627-58-9C10H14N2O
- (3R)-1-(Cyclopropanecarbonyl)piperidine-3-carboxylic acid1567888-63-4C10H15NO3
- (3S)-1-Cyclopropanecarbonylpiperidine-3-carboxylic acid1568196-78-0C10H15NO3
- (4-(Aminomethyl)piperidin-1-yl)(cyclopropyl)methanone915922-83-7C10H18N2O
- Ethyl 1-cyclopropanecarbonylpiperidine-3-carboxylate1153068-27-9C12H19NO3
- 1-Cyclopropanecarbonylpiperidin-3-ol1154910-03-8C9H15NO2
- 1-(Cyclopropylcarbonyl)-N-[1-(hydroxymethyl)propyl]-4-piperidinecarboxamide1156265-30-3C14H24N2O3
- (1-Cyclopropanecarbonylpiperidin-3-yl)methanol1082906-78-2C10H17NO2
- tert-Butyl [1-(cyclopropylcarbonyl)piperidin-3-yl]carbamate2422010-13-5C14H24N2O3
- 1-(Cyclopropylcarbonyl)-3-piperidinamine hydrochloride1158742-26-7C9H17ClN2O
- (3-(Aminomethyl)piperidin-1-yl)(cyclopropyl)methanone915924-36-6C10H18N2O
- 1 suppliers1-Cyclopropanecarbonylpiperidin-4-amine hydrochloride1216823-46-9C9H17ClN2O
- N-[[1-(Cyclopropylcarbonyl)-4-piperidinyl]methyl]carbamic acid 1,1-dimethylethyl ester2055645-32-2C15H26N2O3
- 1-Cyclopropanecarbonyl-4-methoxypiperidine1340884-17-4C10H17NO2
- [1-(Cyclopropylcarbonyl)piperidin-4-yl]acetic acid1284415-59-3C11H17NO3
- 2-(4-Methylpiperidine-1-carbonyl)cyclopropane-1-carboxylic acid1183332-03-7C11H17NO3
- Cyclopropyl(4-(neopentylamino)piperidin-1-yl)methanone1291680-19-7C14H26N2O
- 3-Piperidinecarboxaldehyde, 1-(cyclopropylcarbonyl)-1082481-94-4C10H15NO2
- 4-Ethyl 1-[(2-carboxycyclopropyl)carbonyl]-4-piperidinecarboxylate1178425-74-5C13H19NO5
- 1-Cyclopropanecarbonyl-N-methylpiperidin-4-amine1080651-63-3C10H18N2O
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CC2)cc1130 chemicals
c1ccc(OC2CC2)cc157 chemicals
O=C(c1ccccc1)C1CC128 chemicals
c1ccc(NC2CC2)cc120 chemicals
c1ccc(CC2CO2)cc114 chemicals
c1ccc(SC2CC2)cc114 chemicals
C1COCC(CC2CO2)C111 chemicals
O=S(=O)(c1ccccc1)C1CC110 chemicals
c1ccc(NC2CC2)nc110 chemicals
C1CCN(CC2CC2)CC19 chemicals
O=C(C1CC1)N1CCNCC17 chemicals
c1cncc(OC2CC2)c17 chemicals