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Murcko scaffold

Ring system with 3 rings and 18 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
15
With full pages
3
Scaffold SMILES

C(=Cc1nc2ccccc2[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1nc2ccccc2[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1H-Benzimidazolium, 5,6-dichloro-1-ethyl-2-(2-(phenylamino)ethenyl)-3-(3-sulfobutyl)-, inner salt chemical structure, C21H23Cl2N3O3S, CAS 63148-86-7
1H-Benzimidazolium, 5,6-dichloro-1-ethyl-2-(2-(phenylamino)ethenyl)-3-(3-sulfobutyl)-, inner salt
CAS 63148-86-7C21H23Cl2N3O3S
(2E)-3-[(2,4-Dimethoxyphenyl)amino]-2-(1-methyl-1H-benzimidazol-2-yl)prop-2-enenitrile chemical structure, C19H18N4O2, CAS 1164514-36-6
(2E)-3-[(2,4-Dimethoxyphenyl)amino]-2-(1-methyl-1H-benzimidazol-2-yl)prop-2-enenitrile
CAS 1164514-36-6C19H18N4O2
2-(1H-Benzimidazol-2-yl)-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile chemical structure, C17H11F3N4
2-(1H-Benzimidazol-2-yl)-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile
C17H11F3N4
(E)-2-(1H-Benzo[d]imidazol-2-yl)-3-(p-tolylamino)acrylonitrile chemical structure, C17H14N4, CAS 144581-38-4
(E)-2-(1H-Benzo[d]imidazol-2-yl)-3-(p-tolylamino)acrylonitrile
CAS 144581-38-4C17H14N4
(E)-3-((2-Methoxy-5-methylphenyl)amino)-2-(1-methyl-1H-benzo[d]imidazol-2-yl)acrylonitrile chemical structure, C19H18N4O, CAS 466668-28-0
(E)-3-((2-Methoxy-5-methylphenyl)amino)-2-(1-methyl-1H-benzo[d]imidazol-2-yl)acrylonitrile
CAS 466668-28-0C19H18N4O
(E)-2-(1-Methyl-1H-benzo[d]imidazol-2-yl)-3-(p-tolylamino)acrylonitrile chemical structure, C18H16N4, CAS 466668-19-9
(E)-2-(1-Methyl-1H-benzo[d]imidazol-2-yl)-3-(p-tolylamino)acrylonitrile
CAS 466668-19-9C18H16N4
(E)-Methyl 2-((2-(1H-benzo[d]imidazol-2-yl)-2-cyanovinyl)amino)benzoate chemical structure, C18H14N4O2, CAS 144581-46-4
(E)-Methyl 2-((2-(1H-benzo[d]imidazol-2-yl)-2-cyanovinyl)amino)benzoate
CAS 144581-46-4C18H14N4O2
(E)-3-((2-Ethoxyphenyl)amino)-2-(1-methyl-1H-benzo[d]imidazol-2-yl)acrylonitrile chemical structure, C19H18N4O, CAS 1164536-78-0
(E)-3-((2-Ethoxyphenyl)amino)-2-(1-methyl-1H-benzo[d]imidazol-2-yl)acrylonitrile
CAS 1164536-78-0C19H18N4O
(2E)-2-(1H-Benzimidazol-2-yl)-3-[(3,5-dimethylphenyl)amino]prop-2-enenitrile chemical structure, C18H16N4, CAS 144581-44-2
(2E)-2-(1H-Benzimidazol-2-yl)-3-[(3,5-dimethylphenyl)amino]prop-2-enenitrile
CAS 144581-44-2C18H16N4
(E)-N-((4-((2-Cyano-2-(1-methyl-1H-benzo[d]imidazol-2-yl)vinyl)amino)phenyl)sulfonyl)acetamide chemical structure, C19H17N5O3S, CAS 637748-64-2
(E)-N-((4-((2-Cyano-2-(1-methyl-1H-benzo[d]imidazol-2-yl)vinyl)amino)phenyl)sulfonyl)acetamide
CAS 637748-64-2C19H17N5O3S
2-(1H-1,3-Benzodiazol-2-yl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile chemical structure, C17H11F3N4, CAS 244167-61-1
2-(1H-1,3-Benzodiazol-2-yl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile
CAS 244167-61-1C17H11F3N4
1H-Benzimidazolium, 5,6-dichloro-1-ethyl-2-[2-(phenylamino)ethenyl]-3-(3-sulfopropyl)-, inner salt chemical structure, C20H21Cl2N3O3S, CAS 28094-54-4
1H-Benzimidazolium, 5,6-dichloro-1-ethyl-2-[2-(phenylamino)ethenyl]-3-(3-sulfopropyl)-, inner salt
CAS 28094-54-4C20H21Cl2N3O3S
(E)-Methyl 2-((2-cyano-2-(1-methyl-1H-benzo[d]imidazol-2-yl)vinyl)amino)benzoate chemical structure, C19H16N4O2, CAS 578756-85-1
(E)-Methyl 2-((2-cyano-2-(1-methyl-1H-benzo[d]imidazol-2-yl)vinyl)amino)benzoate
CAS 578756-85-1C19H16N4O2
1H-Benzimidazolium, 5,6-dichloro-1,3-diethyl-2-[2-(phenylamino)ethenyl]-, iodide (1:1) chemical structure, C19H20Cl2IN3, CAS 4751-23-9
1H-Benzimidazolium, 5,6-dichloro-1,3-diethyl-2-[2-(phenylamino)ethenyl]-, iodide (1:1)
CAS 4751-23-9C19H20Cl2IN3
(Z)-2-(1H-Benzimidazol-2-yl)-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile chemical structure, C17H11F3N4
(Z)-2-(1H-Benzimidazol-2-yl)-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile
C17H11F3N4