Murcko scaffold
Morpholin-2-one scaffold
50 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 50
- With full pages
- 3
Scaffold SMILES
O=C1CNCCO1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 50 chemicals
Agropine
CAS 70699-77-3C11H20N2O7
Morpholinium, 4,4-dimethyl-2-oxo-, chloride
CAS 3053-29-0C6H12ClNO2
Morpholin-2-one, 4-nitroso-
CAS 67587-53-5C4H6N2O3
4,4-Diethyl-2-oxomorpholin-4-ium chloride
CAS 2881-29-0C8H16ClNO2
N,N-Diethyl-2-oxomorpholinium
CAS 562841-86-5C8H16NO2+
Morpholinium, 4,4,6-trimethyl-2-oxo-, chloride (1:1)
CAS 2881-30-3C7H14ClNO2
4-Butylmorpholin-2-one
CAS 68182-84-3C8H15NO2
N-Methyl-2-morpholinone
CAS 18424-96-9C5H9NO2
(2-Oxo-morpholin-4-yl)-acetic acid
CAS 302900-65-8C6H9NO4
3-Morpholineacetonitrile, 4-methyl-2-oxo-
CAS 159050-64-3C7H10N2O2
4-(2-Hydroxyethyl)-morpholine-2-one
CAS 5038-12-0C6H11NO3
5-(Hydroxymethyl)-3,5-dimethylmorpholin-2-one
CAS 113464-60-1C7H13NO3
3,3,5,5-Tetramethylmorpholin-2-one
CAS 90032-83-0C8H15NO2
3-Ethyl-3,5,5-trimethylmorpholin-2-one
CAS 90017-19-9C9H17NO2
4-(Propan-2-yl)morpholin-2-one
CAS 18425-30-4C7H13NO2
5,5-Dimethyl-4-propan-2-ylmorpholin-2-one
CAS 136476-54-5C9H17NO2
2-Morpholinone, 3-ethoxy-5,5-dimethyl-4-(1-methylethyl)-
CAS 136476-61-4C11H21NO3
(3S,5S)-3-Methoxy-5-propan-2-ylmorpholin-2-one
CAS 175226-77-4C8H15NO3
3,3,5,5-Tetramethyl-2-oxo-4-morpholinyloxy
CAS 113872-32-5C8H15NO3
2-Morpholinone, 3,3-diethyl-4-hydroxy-5,5-dimethyl-
CAS 468772-74-9C10H19NO3
3,3-Diethyl-5-methyl-5-hydroxymethylmorpholin-2-one
CAS 264279-77-8C10H19NO3
4-Propylmorpholin-2-one
CAS 148854-55-1C7H13NO2
3,5,5-Trimethylmorpholin-2-one
CAS 57765-62-5C7H13NO2
Morpholin-2-one hydrochloride
CAS 2206969-81-3C4H8ClNO2
- 1 suppliersMorpholin-2-one4441-15-0C4H7NO2
- 3,3-Dimethylmorpholin-2-one938374-03-9C6H11NO2
- 4,4-Dimethyl-2-oxomorpholin-4-ium bromide105868-37-9C6H12BrNO2
- 4-Acetyl-3,3-dimethylmorpholin-2-one1011700-95-0C8H13NO3
- (5R)-5-[(2E)-But-2-en-1-yl]morpholin-2-one334994-41-1C8H13NO2
- (3S,5R)-5-Ethenyl-3,5-dimethylmorpholin-2-one205495-79-0C8H13NO2
- (3S,5S)-5-Ethenyl-3,5-dimethylmorpholin-2-one205495-78-9C8H13NO2
- (5S)-5-Methyl-4-propylmorpholin-2-one710654-85-6C8H15NO2
- (3S,5R)-5-Methyl-3-propan-2-ylmorpholin-2-one277302-75-7C8H15NO2
- 5-[(E)-But-2-enyl]morpholin-2-one863554-80-7C8H13NO2
- (2E)-[(2-Oxo-4-morpholinyl)imino]acetonitrile56313-71-4C6H7N3O2
- (3S)-3,5,5-Trimethylmorpholin-2-one1231951-61-3C7H13NO2
- (R)-4-Ethyl-6-methylmorpholin-2-one1312607-96-7C7H13NO2
- 4-Ethyl-6-methylmorpholin-2-oneC7H13NO2
- 2-(4-Ethyl-6,6-dimethyl-2-oxomorpholin-3-yl)acetic acid1312608-17-5C10H17NO4
- (S)-4-Ethyl-6-methylmorpholin-2-one1312607-95-6C7H13NO2
- 4,6,6-Triethylmorpholin-2-one1312608-00-6C10H19NO2
- 2-(4-Ethyl-2-oxomorpholin-3-yl)acetic acid1204519-00-5C8H13NO4
- 4-Methylmorpholin-2-one hydrochloride1820735-05-4C5H10ClNO2
- 1,1-Dimethylethyl 2-oxo-4-morpholinecarboxylate1140502-97-1C9H15NO4
- 3,3-Dimethylmorpholin-2-one, trifluoroacetic acid1820716-74-2C8H12F3NO4
- 5-Ethyl-4-methyl-2-morpholinone19180-81-5C7H13NO2
- Prop-2-en-1-yl 3,3-dimethyl-2-oxomorpholine-4-carboxylate2680771-48-4C10H15NO4
- 2-(4-Ethyl-6,6-dimethyl-2-oxomorpholin-3-yl)acetic acid, trifluoroacetic acid1648907-00-9C12H18F3NO6
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
