Murcko scaffold
Ring system with 2 rings and 14 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 6
- With full pages
- 3
Scaffold SMILES
[N+]=C1C=CC(=Nc2ccccc2)C=C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold [N+]=C1C=CC(=Nc2ccccc2)C=C1](/scaffold/ZSGRTRQPCZXCBS-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
(4-((4,6-Diamino-m-tolyl)imino)cyclohexa-2,5-dien-1-ylidene)dimethylammonium chloride
CAS 97-26-7C15H19ClN4
![N-{4-[(2,4-Diamino-5-methylphenyl)imino]cyclohexa-2,5-dien-1-ylidene}-N-methylmethanaminium chemical structure, C15H19N4+](/s/HKHSSDWRZSCGQF-UHFFFAOYSA-O.svg)
N-{4-[(2,4-Diamino-5-methylphenyl)imino]cyclohexa-2,5-dien-1-ylidene}-N-methylmethanaminium
C15H19N4+
Bindschedler's green
CAS 4486-05-9C16H20ClN3
N-(4-((4-(Dimethylamino)phenyl)imino)cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium
CAS 47005-16-3C16H20N3+
Ammonium, (4-((4,6-diamino-m-tolyl)imino)-2,5-cyclohexadien-1-ylidene)dimethyl-, chloride, monohydrate
CAS 6424-34-6C15H21ClN4O
Zwa32V9mkk
CAS 1698876-57-1C16H19N3O3S2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cc2ccccc2)cc1952 chemicals
c1ccc(Oc2ccccc2)cc1933 chemicals
O=C(c1ccccc1)c1ccccc1537 chemicals
c1ccc(Nc2ccccc2)cc1395 chemicals
c1ccc(CN2CCCCC2)cc1283 chemicals
c1ccc(CN2CCNCC2)cc1267 chemicals
O=S(=O)(c1ccccc1)N1CCCCC1266 chemicals
c1ccc(Oc2ccccn2)cc1238 chemicals
c1ccc(Sc2ccccc2)cc1195 chemicals
O=S(=O)(c1ccccc1)N1CCNCC1195 chemicals
c1ccc(OC2CCCCO2)cc1164 chemicals
O=C(c1ccccc1)N1CCCCC1164 chemicals