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Murcko scaffold

2-(Pyrrolidin-2-yl)pyrimidine scaffold

58 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
58
With full pages
5
Scaffold SMILES

c1cnc(C2CCCN2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-2-yl)pyrimidine page
Murcko scaffold c1cnc(C2CCCN2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 58 chemicals

2-(Pyrrolidin-2-yl)pyrimidine chemical structure, C8H11N3, CAS 944905-56-0
2-(Pyrrolidin-2-yl)pyrimidine
CAS 944905-56-0C8H11N3
2-(Pyrrolidin-2-yl)pyrimidin-4-amine chemical structure, C8H12N4, CAS 1263378-09-1
2-(Pyrrolidin-2-yl)pyrimidin-4-amine
CAS 1263378-09-1C8H12N4
Methyl-(2-pyrrolidin-2-YL-pyrimidin-4-yl)-amine chemical structure, C9H14N4, CAS 1263378-74-0
Methyl-(2-pyrrolidin-2-YL-pyrimidin-4-yl)-amine
CAS 1263378-74-0C9H14N4
2-(Pyrrolidin-2-yl)pyrimidine-4-carbaldehyde chemical structure, C9H11N3O, CAS 944900-56-5
2-(Pyrrolidin-2-yl)pyrimidine-4-carbaldehyde
CAS 944900-56-5C9H11N3O
5-Chloro-2-(pyrrolidin-2-yl)pyrimidine chemical structure, C8H10ClN3, CAS 944901-10-4
5-Chloro-2-(pyrrolidin-2-yl)pyrimidine
CAS 944901-10-4C8H10ClN3
2-[(2S)-Pyrrolidin-2-yl]pyrimidine chemical structure, C8H11N3, CAS 760993-80-4
2-[(2S)-Pyrrolidin-2-yl]pyrimidine
CAS 760993-80-4C8H11N3
2-[(2R)-Pyrrolidin-2-yl]pyrimidine chemical structure, C8H11N3, CAS 871792-66-4
2-[(2R)-Pyrrolidin-2-yl]pyrimidine
CAS 871792-66-4C8H11N3
2-(Pyrrolidin-2-yl)-4-(trifluoromethyl)pyrimidine chemical structure, C9H10F3N3, CAS 1259078-84-6
2-(Pyrrolidin-2-yl)-4-(trifluoromethyl)pyrimidine
CAS 1259078-84-6C9H10F3N3
4,6-Dimethyl-2-(pyrrolidin-2-yl)pyrimidine chemical structure, C10H15N3, CAS 1316220-10-6
4,6-Dimethyl-2-(pyrrolidin-2-yl)pyrimidine
CAS 1316220-10-6C10H15N3
5-Bromo-2-(pyrrolidin-2-yl)pyrimidine chemical structure, C8H10BrN3, CAS 1344005-26-0
5-Bromo-2-(pyrrolidin-2-yl)pyrimidine
CAS 1344005-26-0C8H10BrN3
5-Methyl-2-(pyrrolidin-2-yl)pyrimidine chemical structure, C9H13N3, CAS 1339522-58-5
5-Methyl-2-(pyrrolidin-2-yl)pyrimidine
CAS 1339522-58-5C9H13N3
4-Methyl-2-(pyrrolidin-2-yl)-6-(trifluoromethyl)pyrimidine chemical structure, C10H12F3N3, CAS 1316225-59-8
4-Methyl-2-(pyrrolidin-2-yl)-6-(trifluoromethyl)pyrimidine
CAS 1316225-59-8C10H12F3N3
4-Methyl-2-(pyrrolidin-2-yl)pyrimidine chemical structure, C9H13N3, CAS 1316224-03-9
4-Methyl-2-(pyrrolidin-2-yl)pyrimidine
CAS 1316224-03-9C9H13N3
3-(2-(1-Acetylpyrrolidin-2-yl)-6-methylpyrimidin-4-yl)propanoic acid chemical structure, C14H19N3O3, CAS 1316217-60-3
3-(2-(1-Acetylpyrrolidin-2-yl)-6-methylpyrimidin-4-yl)propanoic acid
CAS 1316217-60-3C14H19N3O3
3-(6-Methyl-2-(1-(methylsulfonyl)pyrrolidin-2-yl)pyrimidin-4-yl)propanoic acid chemical structure, C13H19N3O4S, CAS 1316220-90-2
3-(6-Methyl-2-(1-(methylsulfonyl)pyrrolidin-2-yl)pyrimidin-4-yl)propanoic acid
CAS 1316220-90-2C13H19N3O4S
4-Methyl-2-(pyrrolidin-2-yl)-6-(trifluoromethyl)pyrimidine hydrochloride chemical structure, C10H13ClF3N3, CAS 1361114-66-0
4-Methyl-2-(pyrrolidin-2-yl)-6-(trifluoromethyl)pyrimidine hydrochloride
CAS 1361114-66-0C10H13ClF3N3
N,N,6-trimethyl-2-(pyrrolidin-2-yl)pyrimidin-4-amine dihydrochloride chemical structure, C11H20Cl2N4, CAS 1361112-22-2
N,N,6-trimethyl-2-(pyrrolidin-2-yl)pyrimidin-4-amine dihydrochloride
CAS 1361112-22-2C11H20Cl2N4
4-Methyl-2-(pyrrolidin-2-yl)pyrimidine hydrochloride chemical structure, C9H14ClN3, CAS 1361118-71-9
4-Methyl-2-(pyrrolidin-2-yl)pyrimidine hydrochloride
CAS 1361118-71-9C9H14ClN3
2-Pyrrolidin-2-YL-5-(trifluoromethyl)pyrimidine chemical structure, C9H10F3N3, CAS 944900-14-5
2-Pyrrolidin-2-YL-5-(trifluoromethyl)pyrimidine
CAS 944900-14-5C9H10F3N3
Ethyl 2-(pyrrolidin-2-yl)pyrimidine-5-carboxylate chemical structure, C11H15N3O2, CAS 944902-20-9
Ethyl 2-(pyrrolidin-2-yl)pyrimidine-5-carboxylate
CAS 944902-20-9C11H15N3O2
2-(Pyrrolidin-2-yl)pyrimidine dihydrochloride chemical structure, C8H13Cl2N3, CAS 1373223-29-0
2-(Pyrrolidin-2-yl)pyrimidine dihydrochloride
CAS 1373223-29-0C8H13Cl2N3
tert-Butyl 2-(5-iodopyrimidin-2-yl)pyrrolidine-1-carboxylate chemical structure, C13H18IN3O2, CAS 1817679-13-2
tert-Butyl 2-(5-iodopyrimidin-2-yl)pyrrolidine-1-carboxylate
CAS 1817679-13-2C13H18IN3O2
5-Iodo-2-(pyrrolidin-2-yl)pyrimidine chemical structure, C8H10IN3, CAS 1817679-14-3
5-Iodo-2-(pyrrolidin-2-yl)pyrimidine
CAS 1817679-14-3C8H10IN3
2-(Pyrrolidin-2-yl)-4-(trifluoromethyl)pyrimidine hydrochloride chemical structure, C9H11ClF3N3, CAS 1955557-37-5
2-(Pyrrolidin-2-yl)-4-(trifluoromethyl)pyrimidine hydrochloride
CAS 1955557-37-5C9H11ClF3N3